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MGH researchers identify how Shigella injects proteins into target host cells

Researchers from the Massachusetts General Hospital Division of Infectious Diseases are investigating the mechanism by which several important pathogenic species of bacteria deliver proteins into the cells of the organisms they are infecting.

10 Mar 2016

HIV-positive individuals in Africa with certain genetic variant have lower chance of developing TB

In the first known discovery of its kind, a Case Western Reserve University School of Medicine-led team has found that HIV patients in Africa with a certain genetic variant have a 63-percent lower chance of developing tuberculosis than HIV patients without the genetic variant.

10 Mar 2016

Novel nanoparticle technology can decipher protein structures and help access drug targets

Researchers at Karolinska Institutet, Sweden, have developed a nanoparticle technology that can be used to stabilise membrane proteins so that their structure can be studied in a lipid environment. The method, described in Nature Methods, makes it possible to access drug targets that previously could not be investigated and therefore potentially allows for the development of novel drugs, therapeutic antibodies and vaccines.

9 Mar 2016

Thermo Fisher exhibits new UHPLC-MS workflow solutions for biopharmaceutical characterization at Pittcon 2016

Biopharmaceutical companies can now achieve advanced levels of specificity, sensitivity and speed with specialized analytical workflow solutions for the characterization and quantification of proteins.

From Thermo Fisher Scientific Inc. 9 Mar 2016

Nociceptin could help to reduce effects of asthma attacks

An international team of researchers from the Universities of Leicester and Naples has examined the role of a receptor in the body that could help to prevent or reduce the effects of asthma attacks.

9 Mar 2016

Metabolic syndrome treatment benefits MS patients

Oral antidiabetic medications have beneficial anti-inflammatory effects in patients with multiple sclerosis and metabolic syndrome, providing support for a link between metabolism and autoimmunity, researchers report.

9 Mar 2016

Consuming green tea with dietary iron may lessen health benefits of green tea

Green tea is touted for its many health benefits as a powerful antioxidant, but experiments in a laboratory mouse model of inflammatory bowel disease suggest that consuming green tea along with dietary iron may actually lessen green tea's benefits.

9 Mar 2016

Research findings may provide highly effective therapeutic strategy for treatment of Alzheimer's, AMD

For the first time, researchers at LSU Health New Orleans have shown that a protein critical to the body's ability to remove waste products from the brain and retina is diminished in age-related macular degeneration, after first making the discovery in an Alzheimer's disease brain. The research team, led by Walter Lukiw, PhD, Professor of Neurology, Neuroscience and Ophthalmology at LSU Health New Orleans Neuroscience Center, also discovered a key reason, identifying a new treatment target.

8 Mar 2016

CNIO researchers find panoramic view of proteins that intervene in a cellular process

Three years ago, the research team directed by Óscar Fernández-Capetillo, head of the Genomic Instability Group at the Spanish National Cancer Research Centre, obtained, for the first time, a panoramic view of the proteins that intervene in one of the most important and delicate cellular processes: the copying of genetic material during cellular division. They observed that the parts of the genome where the DNA was copied were also very rich in the modification by some very particular proteins, SUMOylations, and poor in others, ubiquitinations, but they were unable to understand why.

8 Mar 2016

Novel mechanism identified to protect the brain from many neurodegenerative conditions

Scientists at Case Western Reserve University School of Medicine have identified a novel mechanism that could be used to protect the brain from damage due to stroke and a variety of neurodegenerative conditions, including sporadic Creutzfeldt-Jakob disease, Alzheimer's disease, and Parkinson's disease.

8 Mar 2016

Rutgers' new drug candidate may help fight malaria

Malaria killed about 440,000 people - mostly young children - last year, but a new drug candidate discovered at Rutgers may help fight the long-dreaded disease.

8 Mar 2016

Cause of amyloid beta pathology may be more versatile than previously known

Accumulation of the substance amyloid beta in the brain impairs the memory and cognitive ability in people with Alzheimer's. New findings from Lund University in Sweden show that the cause of amyloid beta pathology might be more versatile than previously known. Researchers believe that these new findings may be of significance to the development of new medications.

8 Mar 2016

Researchers discover how E. coli bacteria adhere to urinary tract

Almost every second woman suffers from a bladder infection at some point in her life. Also men are affected by cystitis, though less frequently. In eighty percent of the cases, it is caused by the intestinal bacterium E. coli.

8 Mar 2016

Research could change the way people look at gene expression, immune response

Research from the Single-Cell Genomics Centre on the Wellcome Genome Campus could change the way we look at gene expression and immune response. Published in Nature Methods, the new method, TraCeR, provides a powerful tool for research into immune response, vaccination, cancer and autoimmunity.

8 Mar 2016

Research findings offer new way to look at cancer cell metabolism

Cancer cells are notorious for their ability to divide uncontrollably and generate hordes of new tumor cells. Most of the fuel consumed by these rapidly proliferating cells is glucose, a type of sugar.

8 Mar 2016

NIH scientists show how neurons in the eye may use math to differentiate moving objects

Our eyes constantly send bits of information about the world around us to our brains where the information is assembled into objects we recognize. Along the way, a series of neurons in the eye uses electrical and chemical signals to relay the information. In a study of mice, National Institutes of Health scientists showed how one type of neuron may do this to distinguish moving objects.

8 Mar 2016

Research provides important new insights into beginning stages of primary progressive aphasia

The recent ability to peer into the brain of living individuals with a rare type of language dementia, primary progressive aphasia (PPA), provides important new insights into the beginning stages of this disease -- which results in language loss -- when it is caused by a buildup of a toxic protein found in Alzheimer's disease.

8 Mar 2016

G Protein News and Research

MGH researchers identify how Shigella injects proteins into target host cells

HIV-positive individuals in Africa with certain genetic variant have lower chance of developing TB

Novel nanoparticle technology can decipher protein structures and help access drug targets

Thermo Fisher exhibits new UHPLC-MS workflow solutions for biopharmaceutical characterization at Pittcon 2016

Nociceptin could help to reduce effects of asthma attacks

Metabolic syndrome treatment benefits MS patients

Consuming green tea with dietary iron may lessen health benefits of green tea

Research findings may provide highly effective therapeutic strategy for treatment of Alzheimer's, AMD

CNIO researchers find panoramic view of proteins that intervene in a cellular process

Novel mechanism identified to protect the brain from many neurodegenerative conditions

Rutgers' new drug candidate may help fight malaria

Cause of amyloid beta pathology may be more versatile than previously known

Researchers discover how E. coli bacteria adhere to urinary tract

Research could change the way people look at gene expression, immune response

Research findings offer new way to look at cancer cell metabolism

NIH scientists show how neurons in the eye may use math to differentiate moving objects

Research provides important new insights into beginning stages of primary progressive aphasia

ACGT awards new research grants to take researchers to next level in cancer treatment

Absence of PEMT enzyme leads to development of fatty liver disease and tumours in thin patients

New study sheds light on challenges in addressing post-operative bleeding in newborns

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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