Immune Response News and Research

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Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

A recent research paper by scientists from Denmark reveals that circulating plasmacytoid dendritic cells may be a potential therapeutic target to maintain desired levels of an antiviral compound known as interferon, allowing for the mitigation of coronavirus disease (COVID-19) severity. The study is currently available on the bioRxiv* preprint server while it undergoes peer review.

28 Nov 2021

Using dried blood spots to monitor SARS-CoV-2 antibodies at home

The Roche Elecsys® anti-SARS-CoV-2 S immunoassay was used to demonstrate its ability to measure SARS-CoV-2 antibodies from DBS samples.

28 Nov 2021

Genetic ancestry can explain population-level differences in immune response to the flu virus

A new study aimed at explaining differential susceptibility to viral epidemics reveals that ancestry and associated genetic variation can explain population-level differences in the immune response to the flu virus and perhaps also to COVID-19.

26 Nov 2021

Prediction of severe infection based on SARS-CoV-2 genomic analysis

A group of researchers have used these SARS-CoV-2 sequence data and developed an algorithm to predict severity based upon viral mutations.

26 Nov 2021

Efficacy and safety of an RBD-based recombinant protein COVID-19 vaccine

A study developed a protein-based subunit vaccine, PHH-1V, that consisted of a recombinant RBD fusion heterodimer of the alpha) and beta variants of SARS-CoV-2.

26 Nov 2021

SARS-CoV-2 vaccine based on vesicular stomatitis virus exhibits high neutralizing efficacy against variants

Scientists have tested the efficacy of BriLife®-vaccinated human sera in neutralizing more infectious and probably more virulent SARS-CoV-2 variants.

26 Nov 2021

Immune response to influenza virus influenced by genetic ancestry

New research at the University of Chicago has found differences in immune pathway activation to influenza infection between individuals of European and African genetic ancestry.

25 Nov 2021

A review of natural immunity, vaccines, and variants in SARS-CoV-2 reinfection

In a literature review article published in the Journal of Community Hospital Internal Medicine Perspectives, authors from the US performed a thorough investigation of previous studies and case reports of SARS-CoV-2 reinfection. This review discusses the role of natural immunity, vaccines, and SARS-CoV-2 variants in reinfection.

25 Nov 2021

Study explores adverse effects of SARS-CoV-2-induced antibody responses

The authors of a research paper published in the journal Frontiers in Immunology used Sandwich ELISA tests to determine the distribution of IgG sub-classes and complement activation levels in plasma from convalescent individuals.

25 Nov 2021

Researchers reveal possible role for anti-idiotype antibodies in long-term effects of COVID-19

With around 256 million cases and more than 5 million deaths worldwide, the COVID-19 pandemic has challenged scientists and those in the medical field.

25 Nov 2021

LMU immunologists reveal how Roquin-1 controls the activity of immune cells

LMU immunologists have discovered how mutations in Roquin-1 trigger autoimmunity, but can also improve the body's fight against cancer cells.

25 Nov 2021

Using metal nanoparticles to fight SARS-CoV-2

A recent review article looks at the potential of nanotechnology in fighting severe acute respiratory syndrome 2 (SARS-CoV-2), with several possibilities of strategies in therapeutics, vaccines, and prevention.

25 Nov 2021

Study compares immune responses of patients with and without kidney failure after COVID-19 vaccination

Death rates from COVID-19 are especially high in individuals with kidney failure who are on dialysis, making SARS-CoV-2 vaccination in this population a high priority.

24 Nov 2021

Maternal-fetal interface yields intriguing clues to how it battles SARS-CoV-2

Scientists have hypothesized that the number of immune cells and the amount of cytokines produced in response to SARS-CoV-2 infection in pregnant women change in accordance with the timing of maternal infection in pregnancy. This study is available on the bioRxiv* preprint server.

24 Nov 2021

Impeding SARS‑CoV‑2 evolution by targeting low-probability stochastic events

Researchers explore the emergence of more fit SARS-CoV-2 variants using a stochastic evolutionary modeling framework during long-term infections.

24 Nov 2021

Treatment with antihistamines associated with improved responses to immunotherapy

New research from The University of Texas MD Anderson Cancer Center found that treatment with antihistamines, a commonly used allergy medication, was associated with improved responses to immune checkpoint inhibitors.

24 Nov 2021

SARS-CoV-2 reinfection and the natural immune response

Researchers review available literature on immunity and SARS-CoV-2 infection to elucidate mechanisms behind SARS-CoV-2 immunity and reinfections.

24 Nov 2021

An assessment of potential epitopes in SARS-CoV-2 structural proteins

Researchers utilized multiple bioinformatics resources to identify potent T- and B-cell epitopes of four SARS-CoV-2 structural proteins.

24 Nov 2021

Finding potential biomarkers to predict response to immunotherapy in nonhypermutated cancers

Scientists have discovered a potential biomarker that could more accurately identify which patients with non-hypermutated cancers will respond to specialized immunotherapy drugs called immune checkpoint inhibitors, according to findings published in Science Translational Medicine.

24 Nov 2021

Similar antibody responses to spike protein in COVID-19 survivors and vaccine recipients

Researchers conducted a study on COVID-19 convalescent patients and post-vaccinated populations to identify the minimal levels of antibody required to protect against SARS-CoV-2 infection.

24 Nov 2021

Immune Response News and Research

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

Using dried blood spots to monitor SARS-CoV-2 antibodies at home

Genetic ancestry can explain population-level differences in immune response to the flu virus

Prediction of severe infection based on SARS-CoV-2 genomic analysis

Efficacy and safety of an RBD-based recombinant protein COVID-19 vaccine

SARS-CoV-2 vaccine based on vesicular stomatitis virus exhibits high neutralizing efficacy against variants

Immune response to influenza virus influenced by genetic ancestry

A review of natural immunity, vaccines, and variants in SARS-CoV-2 reinfection

Study explores adverse effects of SARS-CoV-2-induced antibody responses

Researchers reveal possible role for anti-idiotype antibodies in long-term effects of COVID-19

LMU immunologists reveal how Roquin-1 controls the activity of immune cells

Using metal nanoparticles to fight SARS-CoV-2

Study compares immune responses of patients with and without kidney failure after COVID-19 vaccination

Maternal-fetal interface yields intriguing clues to how it battles SARS-CoV-2

Impeding SARS‑CoV‑2 evolution by targeting low-probability stochastic events

Treatment with antihistamines associated with improved responses to immunotherapy

SARS-CoV-2 reinfection and the natural immune response

An assessment of potential epitopes in SARS-CoV-2 structural proteins

Finding potential biomarkers to predict response to immunotherapy in nonhypermutated cancers

Similar antibody responses to spike protein in COVID-19 survivors and vaccine recipients

Understanding the DNA Damage Response in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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