Protein C News and Research

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Researchers discover a novel pathway to wake up dormant neural stem cells

Scientists from Duke-NUS Medical School and the Mechanobiology Institute (MBI) at the National University of Singapore (NUS) have discovered a novel pathway to wake up dormant neural stem cells, offering potential new therapies for neurodevelopmental disorders such as autism, learning disabilities, and cerebral palsy.

13 Aug 2024

Routine lab tests fail to identify reliable biomarkers for long COVID, study finds

Study found no reliable clinical biomarkers for diagnosing PASC (long COVID) from routine laboratory tests, despite minor differences in some measures between infected and non-infected individuals.

13 Aug 2024

Mrc1 protein identified as key to maintaining cell identity during division

In a major scientific breakthrough, researchers have found that a protein called Mrc1 plays a crucial role in ensuring that cells keep their identity as they divide and grow.

13 Aug 2024

Greater plant fat intake associated with lower overall and cardiovascular disease mortality

Researchers determined the relationship between animal and dietary plant fat intake with mortality from cardiovascular disease (CVD) and other causes.

13 Aug 2024

Higher heme iron intake linked to increased risk of type 2 diabetes

Higher intake of heme iron, the type found in red meat and other animal products - as opposed to non-heme iron, found mostly in plant-based foods - was associated with a higher risk of developing type 2 diabetes (T2D) in a new study led by researchers at Harvard T.H. Chan School of Public Health.

13 Aug 2024

Study reveals role of parvalbumin neurons in deep rebound sleep after sleep deprivation

Professor Hiroki R. Ueda (RIKEN Center for Functional Biology, concurrently team lead), Dr. Kazuhiro Kon (at the time of the research, currently a postdoctoral fellow at Johns Hopkins University) and their colleagues at Graduate School of Medicine, The University of Tokyo, have elucidated the importance of proper regulation of the activity of parvalbumin (PV)-expressing neurons, the major inhibitory neurons in the cerebral cortex, in the long, deep sleep (rebound sleep) that occurs after prolonged wakefulness.

13 Aug 2024

AlphaFold accelerates discovery of potential antipsychotic drugs by outperforming traditional methods

Researchers used AlphaFold and homology modeling to identify potent TAAR1 agonists, showing AlphaFold's superior performance in drug discovery for neuropsychiatric conditions.

13 Aug 2024

Researchers develop new method to study critical type of protein modification process

Human proteins undergo a variety of chemical modifications following their synthesis. These modifications regulate their structure, function, and stability.

12 Aug 2024

NIH study finds routine lab tests fall short in diagnosing long COVID

A National Institutes of Health (NIH)-supported study has found that routine lab tests may not be useful in making a long COVID diagnosis for people who have symptoms of the condition

12 Aug 2024

New research identifies key protein complex in cellular quality control

Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer's disease.

12 Aug 2024

Beyond neurons: Glial cells identified as key players in Alzheimer's disease

Memory loss, confusion, speech problems – Alzheimer's disease is the most common cause of dementia, affecting about 35 million people worldwide, and the number is growing.

12 Aug 2024

Emory researchers offer a new perspective on the mechanism behind Alzheimer's disease

New findings out of Emory University are challenging existing theories about the origins of Alzheimer's, the leading cause of dementia in the elderly worldwide.

12 Aug 2024

Study reveals how light-activated macrophages increase their appetite for cancer cells

The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer.

12 Aug 2024

Engineered NK cells with IL-21 show strong antitumor activity against glioblastoma

Natural killer (NK) cells engineered to express interleukin-21 (IL-21) demonstrated sustained antitumor activity against glioblastoma stem cell-like cells (GSCs) both in vitro and in vivo, according to new research from The University of Texas MD Anderson Cancer Center.

12 Aug 2024

Researchers identify key genetic players in dopamine signaling using transparent worms With The Help Of A Tin...

Dopamine, a powerful brain chemical and neurotransmitter, is a key regulator of many important functions such as attention, experiencing pleasure and reward, and coordinating movement.

12 Aug 2024

Type 2 diabetes hinders beta-amyloid clearance and may elevate Alzheimer's risk

People with type 2 diabetes are at increased risk of Alzheimer's disease and other adverse cognitive health issues.

12 Aug 2024

New study links brain cell structures to memory loss in aging and dementia

Researchers assessed whether dendritic spine head diameter in the temporal cortex is a better predictor of episodic memory performance in older adults than synapse quantity, accounting for β amyloid plaques, neurofibrillary tangles, and sex.

12 Aug 2024

Can odors help fight infection? Nematode research suggests so

Researchers from the University of California, Berkeley, used the nematode model Caenorhabditis elegans to determine whether the olfactory nervous system could non-autonomously control the mitochondrial unfolded protein response in response to cellular stress.

12 Aug 2024

Mare milk may be a feasible natural ingredient to prepare yogurt and probiotic ice creams

The suitability of mare milk in manufacturing yogurt-based and probiotic ice creams.

12 Aug 2024

New proteomic clock predicts biological age and major health risks across diverse populations

Study developed a proteomic age clock using plasma proteins to accurately predict biological age and associated health risks, offering a robust tool for forecasting age-related diseases and mortality.

11 Aug 2024

Protein C News and Research

Researchers discover a novel pathway to wake up dormant neural stem cells

Routine lab tests fail to identify reliable biomarkers for long COVID, study finds

Mrc1 protein identified as key to maintaining cell identity during division

Greater plant fat intake associated with lower overall and cardiovascular disease mortality

Higher heme iron intake linked to increased risk of type 2 diabetes

Study reveals role of parvalbumin neurons in deep rebound sleep after sleep deprivation

AlphaFold accelerates discovery of potential antipsychotic drugs by outperforming traditional methods

Researchers develop new method to study critical type of protein modification process

NIH study finds routine lab tests fall short in diagnosing long COVID

New research identifies key protein complex in cellular quality control

Beyond neurons: Glial cells identified as key players in Alzheimer's disease

Emory researchers offer a new perspective on the mechanism behind Alzheimer's disease

Study reveals how light-activated macrophages increase their appetite for cancer cells

Engineered NK cells with IL-21 show strong antitumor activity against glioblastoma

Researchers identify key genetic players in dopamine signaling using transparent worms With The Help Of A Tin...

Type 2 diabetes hinders beta-amyloid clearance and may elevate Alzheimer's risk

New study links brain cell structures to memory loss in aging and dementia

Can odors help fight infection? Nematode research suggests so

Mare milk may be a feasible natural ingredient to prepare yogurt and probiotic ice creams

New proteomic clock predicts biological age and major health risks across diverse populations

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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