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Breakthrough advancements on new molecular mechanism may lead to Parkinson's treatments

More than one million people in the United States are afflicted with Parkinson's disease, a progressive disorder of the brain that affects movement and coordination. The cause is typically unknown, and presently there is no cure for the disease.

19 Oct 2015

UB study sheds light on the root causes of Huntington's disease

We've known for years that the Huntingtin protein (Htt) is responsible for Huntington's disease, a neurodegenerative disorder that diminishes a person's mental and physical abilities.

19 Oct 2015

Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

Three teams of scientists supported by the National Institutes of Health showed that a genetic mutation linked to some forms of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) may destroy neurons by disrupting the movement of materials in and out of the cell's nucleus, or command center where most of its DNA is stored.

19 Oct 2015

BET protein family plays key role in regulation of normal neuronal development and function

Regulation of a family of brain proteins known as bromodomain and extra-terminal domain containing transcription regulators (BETs) plays a key role in normal cognition and behavior, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published advanced online on September 21 and in print October 19 in The Journal of Experimental Medicine.

19 Oct 2015

New zebrafish study provides insights into causes of congenital heart defects

Researchers working with zebrafish at New Zealand's University of Otago have published a study providing new insights into the causes of the congenital heart defects associated with a rare developmental disorder.

16 Oct 2015

Analysis of high-throughput sequencing data reveals new genes linked to chronic lymphocytic leukemia

Johannes Reiter, former PhD student in the group of Krishnendu Chatterjee at the Institute of Science and Technology Austria (IST Austria), is co-author of a Nature paper on genetic alterations that drive the progression and relapse of cancer.

16 Oct 2015

Study suggests combination of MMF and CNIs can protect against rare lymphoma

A study led by Johns Hopkins researchers has linked the immunosuppressive drug mycophenolate mofetil (MMF) to an increased risk of central nervous system (CNS) lymphoma in solid organ transplant patients.

16 Oct 2015

Study shows why cancer anemia therapy stimulates tumor growth

Scientists have shown why a drug widely used to treat chemotherapy-induced anemia in ovarian and breast cancer patients also may shorten survival times in some patients by inadvertently stimulating tumor growth.

16 Oct 2015

Mental health problems, negative peer influences linked to increased dating violence

A new emergency department study from the University of Michigan Injury Center looks deeper at risk and protective factors among teenagers who report dating violence and alcohol use.

16 Oct 2015

Study reveals high rates of preventable cancers in Indigenous peoples of high-income countries

Research published in The Lancet Oncology, led by the International Agency for Research on Cancer (IARC) on the scale and profile of cancer in indigenous peoples of the USA, Canada, Australia and New Zealand has revealed high rates of often preventable cancers including lung and cervical cancer, emphasising the need for targeted prevention strategies in these populations.

16 Oct 2015

Gene therapy preserves vision in canine model of late-stage retinitis pigmentosa

Gene therapy preserved vision in a study involving dogs with naturally occurring, late-stage retinitis pigmentosa, according to research funded by the National Eye Institute (NEI), part of the National Institutes of Health. The findings contribute to the groundwork needed to move gene therapy forward into clinical trials for people with the blinding eye disorder, for which there is currently no cure.

15 Oct 2015

Having a high stress job may increase risk of stroke

Having a high stress job may be linked to a higher risk of stroke, according to an analysis of several studies. The meta-analysis is published in the October 14, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

15 Oct 2015

New $6.7 million project aims to help kidney dialysis patients live longer

Helping kidney dialysis patients have healthier treatment sessions and longer lives is the goal of a new $6.7 million project at the University of Michigan.

15 Oct 2015

Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

An international research team led by scientists at the University of New Mexico Cancer Center discovered and developed a novel ligand peptide-mimic that inhibits abnormal overgrowth of blood vessels in retinal diseases and tumors. The discovery could lead to new drugs that keep cancers from growing. The team published a paper in the journal Science Translational Medicine.

15 Oct 2015

New hope for patients with Duchenne muscular dystrophy

New hope for Duchenne muscular dystrophy (DMD) patients. A mouse genetic study in PLoS Medicine reports that targeting the P2RX7 gene, a purinoreceptor, may halt the progression of DMD.

14 Oct 2015

How important is a mother’s diet before pregnancy? An interview with Dr Matt Silver

In humans, much is already known about the impact of maternal undernutrition during pregnancy, and its impact on growth, development and disease throughout the life course. However, until recently little was known about the effects of the nutritional environment around the time of conception.

14 Oct 2015

Researchers match certain schizophrenia symptoms to features of the brain's anatomy

Using advanced brain imaging, researchers have matched certain behavioral symptoms of schizophrenia to features of the brain's anatomy. The findings, at Washington University School of Medicine in St. Louis, could be a step toward improving diagnosis and treatment of schizophrenia.

14 Oct 2015

X linked News and Research

Breakthrough advancements on new molecular mechanism may lead to Parkinson's treatments

UB study sheds light on the root causes of Huntington's disease

Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

BET protein family plays key role in regulation of normal neuronal development and function

New zebrafish study provides insights into causes of congenital heart defects

Analysis of high-throughput sequencing data reveals new genes linked to chronic lymphocytic leukemia

Study suggests combination of MMF and CNIs can protect against rare lymphoma

Study shows why cancer anemia therapy stimulates tumor growth

Mental health problems, negative peer influences linked to increased dating violence

Study reveals high rates of preventable cancers in Indigenous peoples of high-income countries

Gene therapy preserves vision in canine model of late-stage retinitis pigmentosa

Having a high stress job may increase risk of stroke

New $6.7 million project aims to help kidney dialysis patients live longer

Novel ligand peptide-mimic inhibits abnormal overgrowth of blood vessels, may lead to new anti-cancer drugs

New hope for patients with Duchenne muscular dystrophy

How important is a mother’s diet before pregnancy? An interview with Dr Matt Silver

Researchers match certain schizophrenia symptoms to features of the brain's anatomy

Researchers identify new therapeutic target for Duchenne muscular dystrophy

Forces in external environmental and oxidation are greatest threats to DNA, study finds

Brain areas linked to social behaviors underdeveloped in youths with high functioning ASD

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How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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