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Physicians should not prescribe cognitive enhancers to healthy people

Physicians should not prescribe cognitive enhancers to healthy individuals, states a report being published today in the Canadian Medical Association Journal (CMAJ).

18 Dec 2012

University of North Carolina awards 13th Perl prize to two NTNU-Trondheim scientists

The University of North Carolina at Chapel Hill has awarded the 13th Perl-UNC Neuroscience prize jointly to Edvard and May-Britt Moser at the Norwegian University of Science and Technology (NTNU-Trondheim) in Trondheim, Norway.

17 Dec 2012

Maryland researchers launch groundbreaking study into spread of drug-resistant malaria in Burma

University of Maryland School of Medicine researchers have launched groundbreaking research into the spread of potentially deadly drug-resistant malaria in the developing Southeast Asian nation of Myanmar, also known as Burma.

17 Dec 2012

Human nociception genes mapped out

Researchers have uncovered a “network map” of genes that are involved in pain perception, which they say may help identify new analgesic drugs.

17 Dec 2012

Dantrolene shows promise for treating DMD

A muscle relaxant called dantrolene used for treating malignant hyperthermia boosts the activity of therapies currently being developed to treat the genetic disorder Duchenne muscular dystrophy (DMD), show study findings.

17 Dec 2012

ProMining Therapeutics, Roche to develop small molecule therapeutics for type 2 diabetes mellitus

ProMining Therapeutics, Ltd. today announced a new collaboration with Roche in the field of type 2 diabetes mellitus.

17 Dec 2012

Naurex announces completion of $38M Series B financing

Naurex Inc., a clinical-stage company developing innovative treatments to address unmet needs in psychiatry and neurology, today announced the completion of a $38 million Series B financing led by new investor Baxter Ventures.

17 Dec 2012

Increased life expectancy not benefitting everybody equally: U of T

Global lifespans have risen dramatically in the past 40 years, but the increased life expectancy is not benefitting everybody equally, say University of Toronto researchers. In particular, adult males from low- and middle-income countries are losing ground.

17 Dec 2012

Paternal exposure to cocaine can impair gene expression and behavior in their offspring

Research from the Perelman School of Medicine at the University of Pennsylvania and Massachusetts General Hospital (MGH) reveals that sons of male rats exposed to cocaine are resistant to the rewarding effects of the drug, suggesting that cocaine-induced changes in physiology are passed down from father to son.

17 Dec 2012

Apophysomyces fungus kills 5 people following a massive Joplin tornado

A fast growing, flesh-eating fungus killed 5 people following a massive tornado that devastated Joplin, Mo., according to two new studies based on genomic sequencing by the Translational Genomics Research Institute (TGen) and the U.S. Centers for Disease Control and Prevention (CDC).

16 Dec 2012

Study tracks movements of leukocytes through the kidney

Better targeted treatments for 20 per cent of renal failure patients are on the horizon following a key discovery about the role of white blood cells in kidney inflammation.

16 Dec 2012

Conference addresses issues of innovation for neglected diseases

Medecins Sans Frontieres, the Drugs for Neglected Diseases initiative, and the Mount Sinai School of Medicine this week are hosting a conference in New York, titled "Lives in the Balance: Delivering Medical Innovations for Neglected Patients and Populations," the Philadelphia Inquirer reports.

15 Dec 2012

Two hematology/oncology pharmacists to receive 2012 HOPA Foundation Research Award

The HOPA Foundation Board of Directors is pleased to announce the recipients of the 2012 HOPA Foundation Research Award, Dr. Kamakshi Rao for her project Improving & Defining the Impact & Value of Pharmacists in Stem Cell Transplant, and to Dr. Quan Li, for his project, In Vitro Stability of Erlotinib, Lapatinib and Imatinib in Common Compounding Vehicles.

15 Dec 2012

Endocyte picks Medidata Solutions cloud-based platform to support clinical trials

Biopharmaceutical company Endocyte has selected the Medidata Solutions cloud-based platform to support the execution of multiple ongoing clinical trials focused on the development of targeted therapies for cancer and other serious diseases.

15 Dec 2012

Researchers identify 125 genetic components in temozolomide-resistant, GBM-derived cell line

University of Pittsburgh Cancer Institute (UPCI) researchers have identified over 125 genetic components in a chemotherapy-resistant, brain tumor-derived cell line, which could offer new hope for drug treatment to destroy the cancer cells.

15 Dec 2012

Study describes new, paradoxical characteristics of HER2-negative breast cancer

A multicenter study led by researchers at UC Davis describes new, paradoxical characteristics of the most common type of breast cancer. The findings shed light on how the disease can evade treatment and could improve diagnosis and treatment of breast cancer.

15 Dec 2012

Everolimus therapy might treat Myc-driven lymphoma

Drugs that are used in the clinic to treat some forms of breast and kidney cancer and that work by inhibiting the signaling molecule mTORC1 might have utility in treating some of the more than 15 percent of human cancers driven by alterations in the Myc gene, according to data from a preclinical study published in Cancer Discovery, a journal of the American Association for Cancer Research.

15 Dec 2012

Glutamate linked to suicidal behavior

Researchers have found the first proof that a chemical in the brain called glutamate is linked to suicidal behavior, offering new hope for efforts to prevent people from taking their own lives.

15 Dec 2012

Bayer files radium-223 NDA with FDA for treatment of CRPC patients with bone metastases

Bayer HealthCare today announced that the company has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking approval for radium Ra 223 dichloride (radium-223), an investigational compound for the treatment of castration-resistant prostate cancer (CRPC) patients with bone metastases.

15 Dec 2012

New finding likely to fuel cost-benefit debate over cancer care

A study published Thursday in the Journal of the National Cancer Institute concluded that proton-beam therapy provided no long-term benefit over traditional radiation despite far higher costs.

15 Dec 2012

Drugs News and Research

Physicians should not prescribe cognitive enhancers to healthy people

University of North Carolina awards 13th Perl prize to two NTNU-Trondheim scientists

Maryland researchers launch groundbreaking study into spread of drug-resistant malaria in Burma

Human nociception genes mapped out

Dantrolene shows promise for treating DMD

ProMining Therapeutics, Roche to develop small molecule therapeutics for type 2 diabetes mellitus

Naurex announces completion of $38M Series B financing

Increased life expectancy not benefitting everybody equally: U of T

Paternal exposure to cocaine can impair gene expression and behavior in their offspring

Apophysomyces fungus kills 5 people following a massive Joplin tornado

Study tracks movements of leukocytes through the kidney

Conference addresses issues of innovation for neglected diseases

Two hematology/oncology pharmacists to receive 2012 HOPA Foundation Research Award

Endocyte picks Medidata Solutions cloud-based platform to support clinical trials

Researchers identify 125 genetic components in temozolomide-resistant, GBM-derived cell line

Study describes new, paradoxical characteristics of HER2-negative breast cancer

Everolimus therapy might treat Myc-driven lymphoma

Glutamate linked to suicidal behavior

Bayer files radium-223 NDA with FDA for treatment of CRPC patients with bone metastases

New finding likely to fuel cost-benefit debate over cancer care

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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