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Scientists discover FAIM molecule as potential biomarker for bone marrow cancer

Singapore scientists have identified FAIM, a molecule that typically prevents cell death, as a potential biomarker to identify an incurable form of cancer in the bone marrow.

14 Dec 2012

EZH2 protein enables advanced prostate cancers to spread without stimulation by male hormones

Scientists at Dana-Farber Cancer Institute have discovered a molecular switch that enables advanced prostate cancers to spread without stimulation by male hormones, which normally are needed to spur the cancer's growth. They say the finding could lead to a new treatment for prostate cancers that are no longer controlled by hormone-blocking drugs.

14 Dec 2012

Scientists isolate cancer stem cells that lead to growth of Wilms' tumours

Scientists have isolated cancer stem cells that lead to the growth of Wilms' tumours, a type of cancer typically found in the kidneys of young children. The researchers have used these cancer stem cells to test a new therapeutic approach that one day might be used to treat some of the more aggressive types of this disease.

13 Dec 2012

Champions Oncology operating revenues increase to $3.6M for six months ended October 31, 2012

Champions Oncology, Inc. (OTC: CSBR), engaged in the development of advanced technology solutions and services to personalize the development and use of oncology drugs, announced today its financial results for the fiscal quarter ended October 31, 2012.

13 Dec 2012

Fatal imbalance between global disease burden and drug development

Despite important progress in research and development (R&D) for global health over the past decade, only a small fraction of new medicines developed between 2000 and 2011 were for the treatment of neglected diseases, highlighting the 'fatal imbalance' between global disease burden and drug development for some of the world most devastating illnesses, said Doctors Without Borders/M-decins Sans Fronti-res (MSF) and the Drugs for Neglected Diseases initiative (DNDi), in an analysis to be presented today at an international conference aimed at spurring medical innovations for these diseases.

13 Dec 2012

New way to effectively make designer drugs that hit collections of protein targets simultaneously

An international research collaboration led by scientists at the University of North Carolina School of Medicine and the University of Dundee, in the U.K., have developed a way to efficiently and effectively make designer drugs that hit multiple protein targets at once.

13 Dec 2012

Opioids already in the body can enhance malignant tendencies of human cancer cells

A study led by University of Chicago researcher Patrick A. Singleton, Ph.D. and published in the journal Anesthesiology has shown that, even without the addition of further opioids such as morphine, opioids already in the body can enhance the malignant tendencies of human cancer cells.

13 Dec 2012

Fiscal talks continue with new round of proposals, finger-pointing

With the deadline looming, President Barack Obama and House Speaker John Boener, R-Ohio, traded new fiscal offers but appeared no closer to a deal. Boehner is pushing for more specifics on how Obama would cut safety net programs, while the White House continues to press for tax increases for the wealthy.

13 Dec 2012

AZD6765 briefly improves treatment-resistant patients' depression symptoms in minutes

A drug that works through the same brain mechanism as the fast-acting antidepressant ketamine briefly improved treatment-resistant patients' depression symptoms in minutes, with minimal untoward side effects, in a clinical trial conducted by the National Institutes of Health. The experimental agent, called AZD6765, acts through the brain's glutamate chemical messenger system.

13 Dec 2012

Dantrolene may help combat Duchenne muscular dystrophy in boys

Drugs are currently being tested that show promise in treating patients with Duchenne muscular dystrophy (DMD), an inherited disease that affects about one in 3,600 boys and results in muscle degeneration and, eventually, death.

13 Dec 2012

New listening device monitors effectiveness of kidney stone treatment

A new listening device, developed by scientists from the University of Southampton, is being used to monitor the effectiveness of the treatment of kidney stones - saving patients unnecessary repeat therapy and x-ray monitoring.

13 Dec 2012

Researchers discover a trigger by which the HCV enters liver cells

Researchers at the University of Southern California (USC) have discovered a trigger by which the Hepatitis C virus enters liver cells ─ shedding light on how this serious and potentially deadly virus can begin to damage the liver.

13 Dec 2012

Georgetown University Women’s Center launches Squash Diabetes campaign

The Squash Diabetes Campaign was launched today by the Georgetown University Women's Squash Team, where a team member successfully competes in the vigorous game of squash despite the health challenges of Type 1 (Juvenile) diabetes.

13 Dec 2012

Delayed childbearing may protect against triple-negative breast cancer

Younger women who wait at least 15 years after their first menstrual period to give birth to their first child may reduce their risk of an aggressive form of breast cancer by up to 60 percent, according to a Fred Hutchinson Cancer Research Center study.

12 Dec 2012

Viewpoints: Pelosi says higher Medicare age 'doesn't work;' Marketplace's clout could lower seniors' drug costs

In the talks to avert the fiscal cliff, the idea of raising the Medicare age is central to the Republican proposal. There's just one critical problem: It doesn't work. It doesn't have public support. It's unfair. And it doesn't lower health expenditures. Such a proposal is a reflection of the broader Republican plan: an assault on the middle class, seniors -- and our future.

12 Dec 2012

TKI-resistant human leukemia stem cells are the source of genomic instability

An international team of scientists, led by researchers from Temple University School of Medicine, has found that a source of mounting genomic chaos, or instability, common to chronic myeloid leukemia (CML) may lie in a pool of leukemia stem cells that are immune to treatment with potent targeted anticancer drugs.

12 Dec 2012

Review describes current state of lung cancer care

A review in the December issue of the journal Archives of Pathology & Laboratory Medicine by Paul Bunn Jr, MD, University of Colorado Cancer Center investigator and past president of ASCO, IASLC and AACI describes the current state of lung cancer care.

12 Dec 2012

Drugs that bind to specific serotonin receptors can improve and impair female sexual function

Drugs that bind to specific serotonin receptors in the brain can both improve and impair female sexual function in non-human primates.

12 Dec 2012

Children with post-traumatic stress disorder (PTSD) may benefit from psychological therapies

Children suffering post-traumatic stress disorder (PTSD) as a result of traumatic events, including child abuse, may benefit from psychological therapies, according to a review published in The Cochrane Library.

12 Dec 2012

Industry sponsored clinical trials present a more favourable picture of reported findings

Studies reporting the results of industry sponsored clinical trials present a more favourable picture of the effects of drugs and medical devices than those reporting on non-industry sponsored trials, according to a new Cochrane systematic review. The researchers call for a rethink of the way that industry bias is handled in medical guidelines and reviews.

12 Dec 2012

Drugs News and Research

Scientists discover FAIM molecule as potential biomarker for bone marrow cancer

EZH2 protein enables advanced prostate cancers to spread without stimulation by male hormones

Scientists isolate cancer stem cells that lead to growth of Wilms' tumours

Champions Oncology operating revenues increase to $3.6M for six months ended October 31, 2012

Fatal imbalance between global disease burden and drug development

New way to effectively make designer drugs that hit collections of protein targets simultaneously

Opioids already in the body can enhance malignant tendencies of human cancer cells

Fiscal talks continue with new round of proposals, finger-pointing

AZD6765 briefly improves treatment-resistant patients' depression symptoms in minutes

Dantrolene may help combat Duchenne muscular dystrophy in boys

New listening device monitors effectiveness of kidney stone treatment

Researchers discover a trigger by which the HCV enters liver cells

Georgetown University Women’s Center launches Squash Diabetes campaign

Delayed childbearing may protect against triple-negative breast cancer

Viewpoints: Pelosi says higher Medicare age 'doesn't work;' Marketplace's clout could lower seniors' drug costs

TKI-resistant human leukemia stem cells are the source of genomic instability

Review describes current state of lung cancer care

Drugs that bind to specific serotonin receptors can improve and impair female sexual function

Children with post-traumatic stress disorder (PTSD) may benefit from psychological therapies

Industry sponsored clinical trials present a more favourable picture of reported findings

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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