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Finding non-invasive nuclear medicine technique to predict effectiveness of therapy for tumors

Researchers have taken a critical step toward developing a non-invasive nuclear medicine technique that can predict the effectiveness of therapy for cancerous tumors, allowing for personalized, precision treatment.

13 Dec 2019

New method to accurately assess dietary intake of bioactives

A new, objective way of measuring flavanol intake has been developed, which could help nutritional experts assess the link between these compounds and their health benefits at scale.

12 Dec 2019

Study suggests antiarrhythmic drug as potential treatment for pulmonary arterial hypertension

High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a potentially fatal disease caused by obstruction of blood flow in the lungs.

12 Dec 2019

Genetic variant mainly found in individuals of African ancestry increases odds of heart failure

A genetic variant in the gene transthyretin (TTR)- which is found in about 3 percent of individuals of African ancestry- is a more significant cause of heart failure than previously believed, according to a multi-institution study led by researchers at Penn Medicine.

10 Dec 2019

Study provides insight into biological effect of aging on cardiovascular disease

Aging adults are more likely to have - and die from - cardiovascular disease than their younger counterparts. New basic science research finds reason to link biological aging to the development of narrowed, hardened arteries, independent of other risk factors like high cholesterol.

10 Dec 2019

New nanoparticle innovation detects vascular calcification in atherosclerosis

Heart disease and stroke are the world's two most deadly diseases, causing over 15 million deaths in 2016 according to the World Health Organization.

9 Dec 2019

Research shows how high levels of blood fat induce inflammation and organ damage

Viral and bacterial infections are not the only causes of inflammation of body tissue. It has been known for some time that certain fat molecules in our bloodstream can also trigger an inflammatory response.

9 Dec 2019

Treating the whole patient essential for older people with cardiovascular disease

Geriatric conditions such as frailty and cognitive impairments may inadvertently worsen when older patients are treated in cardiac intensive care units - even as they receive excellent care for their heart attack, heart failure, valvular heart disease or pulmonary embolism, according to a new scientific statement from the American Heart Association, published today in the Association's premier journal Circulation.

9 Dec 2019

New tool can rapidly reveal unintended changes made by CRISPR-directed gene editing

Amidst rising hopes for using CRISPR gene editing tools to repair deadly mutations linked to conditions like cystic fibrosis and sickle cell disease, a new study in the Nature journal Communications Biology describes a new innovation that could accelerate this work by rapidly revealing unintended and potentially harmful changes introduced by a gene editing process.

6 Dec 2019

Genetically engineered living hydrogel material facilitates intestinal wound healing

About 1.6 million people in the US alone currently have lifelong and incurable Inflammatory Bowel Disease (IBD) including Crohn's disease and ulcerative colitis, and 70,000 new cases are diagnosed in the USA each year.

6 Dec 2019

New dialysis approach provides high levels of satisfaction for kidney patients

A new study reports high levels of patient satisfaction with a minimally invasive approach to creating vascular access for kidney patients who require hemodialysis.

5 Dec 2019

UPV researchers develop new methodology to monitor patients with glioblastoma

Glioblastoma is the most aggressive brain tumor in adults. Now, it can be treated with neurosurgery, radiotherapy and chemotherapy. Still, the median life expectancy of patients affected with this pathology is no longer than 15 months.

5 Dec 2019

ADDF announces new awards through its Diagnostics Accelerator initiative

The Alzheimer's Drug Discovery Foundation announced six new investments totaling $6 million through its Diagnostics Accelerator initiative.

4 Dec 2019

New study could help prevent fatal infections in babies

Premature infants born before 28-30 weeks of life are at high risk for many complications, among which the chances of dying from an infection starting in the intestine are very great. A new study published in the journal Nature Medicine reports that such infections are very much more likely if something interferes with the normal microbial accumulation in the gut. Adding certain bacterial strains protects against such infections, on the other hand.

3 Dec 2019

Novel approach to reach the most difficult-to-access physiological locations

A team led by Professor Sylvain Martel at the Polytechnique Montréal Nanorobotics Laboratory has developed a novel approach to tackling one of the biggest challenges of endovascular surgery: how to reach the most difficult-to-access physiological locations.

3 Dec 2019

New human colon-on-a-chip enables in vitro study of mucus physiology

We have a mutualistic but complicated relationship with the collection of microbes in our gut known as the intestinal microbiome.

3 Dec 2019

Novel remote-controlled 'smart' platform aids in treatment of cardiovascular disease

According to the World Health Organization, cardiovascular disease has become the leading cause of death worldwide. However, vascular regeneration is a promising treatment for cardiovascular disease. Remodeling the endothelium - i.e., forming a confluent vascular endothelial cell monolayer on the lumen - plays a vital role in this process.

3 Dec 2019

Inhibition of a protease could improve the treatment of IBD, study shows

Scientists at the Centro Nacional de Investigaciones Cardiovasculares and the Centro de Investigaciones Biológicas of the Consejo Superior de Investigaciones Científicas have identified the protease MT1-MMP as a possible future target for drugs to treat inflammatory bowel disease.

3 Dec 2019

Strategies for improving drug delivery to treat brain tumors

Despite improvements in drug delivery mechanisms, treating brain tumors has remained challenging.

2 Dec 2019

Blood proteins could help provide a comprehensive 'liquid health check' in future

Proteins in our blood could in future help provide a comprehensive 'liquid health check', assessing our health and predicting the likelihood that we will we will develop a range of diseases, according to research published today in Nature Medicine.

2 Dec 2019

Vascular News and Research

Finding non-invasive nuclear medicine technique to predict effectiveness of therapy for tumors

New method to accurately assess dietary intake of bioactives

Study suggests antiarrhythmic drug as potential treatment for pulmonary arterial hypertension

Genetic variant mainly found in individuals of African ancestry increases odds of heart failure

Study provides insight into biological effect of aging on cardiovascular disease

New nanoparticle innovation detects vascular calcification in atherosclerosis

Research shows how high levels of blood fat induce inflammation and organ damage

Treating the whole patient essential for older people with cardiovascular disease

New tool can rapidly reveal unintended changes made by CRISPR-directed gene editing

Genetically engineered living hydrogel material facilitates intestinal wound healing

New dialysis approach provides high levels of satisfaction for kidney patients

UPV researchers develop new methodology to monitor patients with glioblastoma

ADDF announces new awards through its Diagnostics Accelerator initiative

New study could help prevent fatal infections in babies

Novel approach to reach the most difficult-to-access physiological locations

New human colon-on-a-chip enables in vitro study of mucus physiology

Novel remote-controlled 'smart' platform aids in treatment of cardiovascular disease

Inhibition of a protease could improve the treatment of IBD, study shows

Strategies for improving drug delivery to treat brain tumors

Blood proteins could help provide a comprehensive 'liquid health check' in future

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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