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Viewpoints: David Brooks' formula to avoid Cliff; Krugman says control costs, don't cut coverage

Republicans should go to the White House and say they are willing to see top tax rates go up to 36 percent or 37 percent and they are willing to forgo a debt-ceiling fight for this year.

5 Dec 2012

psi-GSH prevents neurodegeneration associated with Alzheimer's in mouse model

Researchers at the University of Minnesota's Center for Drug Design have developed a synthetic compound that, in a mouse model, successfully prevents the neurodegeneration associated with Alzheimer's disease.

4 Dec 2012

Opinion pieces, editorial address global AIDS response

U.S. Secretary of State Hillary Clinton on Thursday announced the Obama administration's "President's Emergency Plan for AIDS Relief (PEPFAR) Blueprint: Creating an AIDS-free Generation", and the international community recognized World AIDS Day on December 1.

4 Dec 2012

Childhood HIV risks becoming neglected disease as fewer children born with HIV, experts warn

"The success in reducing the number of children born with HIV is in danger of leaving children who already have the disease with poor access to treatment, experts in HIV and AIDS have warned," BMJ reports.

4 Dec 2012

Certain patients with prostate cancer may benefit from Provenge clinical trial

Select patients with advanced prostate cancer may benefit from a Georgia Health Sciences University Cancer Center clinical trial that looks to improve survival rates of the FDA-approved prostate cancer drug Provenge.

4 Dec 2012

Enzalutamide shows promise in treating triple-negative and estrogen-positive breast cancer

Breast cancers are defined by their drivers - estrogen and progesterone receptors (ER and PR) and HER2 are the most common, and there are drugs targeting each. When breast cancer has an unknown driver, it also has fewer treatment options - this aggressive form of breast cancer without ER, PR or HER2, which was thought not to be driven by hormones, is known as triple negative.

3 Dec 2012

Scientists discover new target molecule for development of treatment against Alzheimer's

Scientists from VIB and KU Leuven have discovered a new target molecule for the development of a treatment against Alzheimer's disease. There is currently no cure for this disease.

3 Dec 2012

Pain can be treated by targeting immune and nerve cells outside brain or spinal cord

The treatment of inflammatory pain can be improved by endogenous opioid peptides acting directly in injured tissue. Scientists at the Charité - Universitätsmedizin Berlin and the Université Paris Descartes showed that pain can be successfully treated by targeting immune and nerve cells outside the brain or spinal cord.

3 Dec 2012

Stem cells give insight into path of cytomegalovirus infection

Primitive human stem cells are resistant to human cytomegalovirus, say researchers who believe this finding could provide further insight into disease pathology.

3 Dec 2012

Specific transporters could be exploited to deliver toxic substances into cancer cells

Whitehead Institute scientists report that certain molecules present in high concentrations on the surfaces of many cancer cells could be exploited to funnel lethal toxic molecules into the malignant cells. In such an approach, the overexpression of specific transporters could be exploited to deliver toxic substances into cancer cells.

3 Dec 2012

Heart attack centres: an interview with Dr Sayan Sen

Heart attack networks are designed to facilitate the rapid transfer of heart attack patients to centres with facilities that allow the manual unblocking of the coronary artery with angioplasty.

3 Dec 2012

Scientists identify 15 new genetic regions associated with coronary artery disease

Fifteen new genetic regions associated with coronary artery disease have been identified by a large, international consortium of scientists - including researchers at the Stanford University School of Medicine - taking a significant step forward in understanding the root causes of this deadly disease. The new research brings the total number of validated genetic links with heart disease discovered through genome-wide association studies to 46.

3 Dec 2012

New laser surgical technique appears to be safe and effective in treating epilepsy

A developing new laser surgical technique for epilepsy appears to be safe and effective and reduces hospital stays to one or two days, according to two research reports presented today during the American Epilepsy Society 66th Annual Meting at the San Diego Convention Center.

3 Dec 2012

Scientists demonstrate how glowing fish can help screen drugs that control metabolic disorders

A tiny, translucent zebrafish that glows green when its liver makes glucose has helped an international team of researchers identify a compound that regulates whole-body metabolism and appears to protect obese mice from signs of metabolic disorders.

2 Dec 2012

Fiscal cliff: Dems, GOP sparring publicly over entitlement cuts, including Medicare

President Barack Obama is ready to entertain Republican proposals for spending cuts, but GOP lawmakers must first commit to higher tax rates on the rich and specify what additional spending cuts they want in a deal to avoid the looming "fiscal cliff," Treasury Secretary Timothy Geithner said. "The ball really is with them now," Geithner, one of the president's chief negotiators with Capitol Hill, said during appearances on five Sunday talk shows.

2 Dec 2012

Negative perceptions about generic drugs are more widespread among ethnic minorities

Negative perceptions about generic drugs are more widespread among ethnic minorities than among whites, finds a new study in Ethnicity & Disease.

1 Dec 2012

University of Washington team develops electrically spun cloth to prevent pregnancy, HIV

The only way to protect against HIV and unintended pregnancy today is the condom. It's an effective technology, but not appropriate or popular in all situations.

1 Dec 2012

Researchers uncover molecular structure of master regulator central to melanoma

With the X-ray vision of DESY's light source DORIS, a research team from Hamburg and Iceland has uncovered the molecular structure of a master regulator central to the most deadly form of skin cancer, melanoma.

1 Dec 2012

Viewpoints: Fighting to a draw on Medicare; A coming era of austerity

Since Nov. 6, Republicans have, for perfectly understandable reasons, expressed their deep disappointment with the election results. But even in defeat something significant and positive occurred: Republicans fought Democrats to a draw on the issue of Medicare.

1 Dec 2012

Epidural steroid injections for back pain increase risk of bone loss in postmenopausal women

Postmenopausal women suffered significant bone density loss in their hip after they were treated with an epidural steroid injection for back pain relief, according to a Henry Ford Hospital study

1 Dec 2012

Drugs News and Research

Viewpoints: David Brooks' formula to avoid Cliff; Krugman says control costs, don't cut coverage

psi-GSH prevents neurodegeneration associated with Alzheimer's in mouse model

Opinion pieces, editorial address global AIDS response

Childhood HIV risks becoming neglected disease as fewer children born with HIV, experts warn

Certain patients with prostate cancer may benefit from Provenge clinical trial

Enzalutamide shows promise in treating triple-negative and estrogen-positive breast cancer

Scientists discover new target molecule for development of treatment against Alzheimer's

Pain can be treated by targeting immune and nerve cells outside brain or spinal cord

Stem cells give insight into path of cytomegalovirus infection

Specific transporters could be exploited to deliver toxic substances into cancer cells

Heart attack centres: an interview with Dr Sayan Sen

Scientists identify 15 new genetic regions associated with coronary artery disease

New laser surgical technique appears to be safe and effective in treating epilepsy

Scientists demonstrate how glowing fish can help screen drugs that control metabolic disorders

Fiscal cliff: Dems, GOP sparring publicly over entitlement cuts, including Medicare

Negative perceptions about generic drugs are more widespread among ethnic minorities

University of Washington team develops electrically spun cloth to prevent pregnancy, HIV

Researchers uncover molecular structure of master regulator central to melanoma

Viewpoints: Fighting to a draw on Medicare; A coming era of austerity

Epidural steroid injections for back pain increase risk of bone loss in postmenopausal women

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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