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Study provides personalized strategies to boost AIAA compliance in breast cancer patients

Aromatase inhibitor-associated arthralgia (AIAA) is a major side effect in breast cancer survivors, producing joint pain so severe that as many as ten percent of women discontinue their therapy prematurely while undergoing treatment with these lifesaving drugs.

3 Jun 2010

U-M researchers one step closer to discovering why certain diseases affect specific organs

Why do some diseases affect only specific organs, leaving others invulnerable? Researchers from the University of Michigan have found neural tissue contains imbalanced levels of proteins, which may explain the brain's susceptibility to a debilitating childhood movement disorder.

3 Jun 2010

Life Technologies, DKFZ collaborate to create National High-Throughput Sequencing Center

Life Technologies Corporation and the German Cancer Research Center (Deutsches Krebsforschungszentrum or DKFZ) today announced their collaboration to create the National High-Throughput Sequencing Center. This exclusive partnership will create the largest sequencing facility in Germany and the first national sequencing center in Europe dedicated to systems biology.

3 Jun 2010

Researchers discover relationship between DNA methylation and positioning of nucleosomes

A previously unknown pattern in DNA methylation - an event that affects cell function by altering gene expression - has been uncovered for the first time by stem cell researchers at UCLA, a finding that could have implications in preventing some cancers and correcting defects in human stem cell lines.

3 Jun 2010

Research explains brain's susceptibility to dystonia

3 Jun 2010

Researchers describe chain of molecular events that increase one's risk of skin cancer

As people head to the beach this summer, very few if any, really know how likely they are to develop skin cancer from their outdoor fun. That's about to change, thanks to a new discovery by an international team of scientists that makes it possible for doctors to access people's personal risk for skin cancer.

3 Jun 2010

Asuragen obtains license to integrate BRAF V600E mutation sequence into its molecular diagnostic products

Asuragen, Inc., a leader in molecular diagnostics and RNA-based pharmacogenomics services, announced today that it has obtained a non-exclusive license to incorporate the BRAF V600E mutation sequence into Asuragen's molecular diagnostic products. The license was obtained from Johns Hopkins University and includes the use of the BRAF V600E mutation as a component of diagnostic test kits and for use in Asuragen's CLIA laboratory for clinical research and patient testing.

2 Jun 2010

Genes influence AIAA side effect in breast cancer survivors

2 Jun 2010

Ablexis to advance transgenic mouse platform for antibody discovery with $12M Series A financing

Ablexis, LLC, a biotechnology company dedicated to developing an innovative, next-generation platform for antibody drug discovery, announced today that it has completed a $12 million Series A financing. The round was led by Third Rock Ventures and included Pfizer Venture Investments. Proceeds from the financing will be used to continue advancing Ablexis' proprietary AlivaMab Mouse transgenic mouse platform for the discovery of human therapeutic antibodies.

2 Jun 2010

New research project to discover origin of myelodysplasia

The University of Navarra, together with the University of Oxford and three other European centres, are taking part in a project to discover the origin of myelodysplasia, an ailment with a predisposition to develop into leukaemia. In the work, patients from 19 hospitals in the north of Spain - including the University Hospital of Navarra - were analysed, as well as from England, Italy, Sweden and Germany.

2 Jun 2010

Paid parental leave in Australia may soon be a reality

Australia’s Liberal opposition has allowed the Rudd government to implement the paid parental leave scheme with effect from 1st January 2011. As per this scheme both parents will get an 18 weeks' paid leave at the minimum wage rate of $543 a week. At present Australia is one of the only two OECD countries that does not have a paid parental scheme.

1 Jun 2010

Consent forms for research: Have they improved in 25 years?

The consent forms that people sign before participating in research are widely considered difficult to understand and sometimes inaccurate. The lack of clarity was implicated in a high-profile legal settlement in April between Arizona State University and a Native American tribe, which claimed that blood samples that its members provided for genetic research were used for purposes not stated in the consent form. Efforts have been made to improve the forms, but how effective are they?

1 Jun 2010

Research team confirms gene mutation associated with serious forms of leukaemia

1 Jun 2010

MediSapiens completes $1M seed round investment for personalized cancer medicine software

MediSapiens, world's first software company for personalized cancer medicine in oncology clinics and drug development, completed $ 1 million (EUR 0.8 million) seed round investment from Veraventure, ETFIII advised by Eqvitec Partners, VTT Ventures and Lifeline Ventures.

1 Jun 2010

Commonalities between flies and humans make valuable new model for galactosemia

Galactosemia is a metabolic disease resulting from an inherited defect that prevents the proper metabolism of galactose, a sugar commonly found in dairy products, like milk. Exposure of affected people to galactose, can damage most of their organ systems and can be fatal. The ability to study the disease is limited by a lack of animal models.

1 Jun 2010

Karolinska Institutet researchers produce human stem cells without using animal substances

For the first time, human embryonic stem cells have been cultured under chemically controlled conditions without the use of animal substances, which is essential for future clinical uses. The method has been developed by researchers at Karolinska Institutet and is presented in the journal Nature Biotechnology.

31 May 2010

DNAzymes and substrates constitute a platform for logic operations essential to computational processes

New perspectives are opening up in bio-engineering thanks to research jointly carried out by teams of chemists at the University of Liège and the Hebrew University of Jerusalem within the framework of the European MOLOC project (Molecular Logic Circuits). This work has led to the publication of two important publications, one straight after the other, in the Nature Nanotechnology journal.

31 May 2010

Scientists identify new susceptibility genes in genome-wide association study of nasopharyngeal carcinoma

Scientists from Singapore, China and USA have identified three new susceptibility genes in a genome-wide association study of nasopharyngeal carcinoma (NPC). The study, led by the Genome Institute of Singapore (GIS), a biomedical research institute of the Agency for Science, Technology and Research (A*STAR), and the Sun Yat-Sen University Cancer Centre, identified genetic risk factors of NPC that advance the understanding of the important role played by host genetic variation in influencing the susceptibility to this cancer.

31 May 2010

Researchers identify gene responsible for Meckel-Gruber and Joubert syndromes

An international group of researchers has identified the genetic cause of an inherited condition that causes severe foetal abnormalities.

31 May 2010

Various aspects of consumer genetics to be discussed at 2nd Annual Consumer Genetics Conference

At the 2nd Annual Consumer Genetics Conference taking place in Boston from June 2-4 at the Hynes Convention Center, these issues will be addressed and preeminent leaders from varying areas of expertise will provide perspectives on these crucial topics that are shaping the way we approach clinical medicine and helping to improve patient outcomes.

29 May 2010

Genetic News and Research

Study provides personalized strategies to boost AIAA compliance in breast cancer patients

U-M researchers one step closer to discovering why certain diseases affect specific organs

Life Technologies, DKFZ collaborate to create National High-Throughput Sequencing Center

Researchers discover relationship between DNA methylation and positioning of nucleosomes

Research explains brain's susceptibility to dystonia

Researchers describe chain of molecular events that increase one's risk of skin cancer

Asuragen obtains license to integrate BRAF V600E mutation sequence into its molecular diagnostic products

Genes influence AIAA side effect in breast cancer survivors

Ablexis to advance transgenic mouse platform for antibody discovery with $12M Series A financing

New research project to discover origin of myelodysplasia

Paid parental leave in Australia may soon be a reality

Consent forms for research: Have they improved in 25 years?

Research team confirms gene mutation associated with serious forms of leukaemia

MediSapiens completes $1M seed round investment for personalized cancer medicine software

Commonalities between flies and humans make valuable new model for galactosemia

Karolinska Institutet researchers produce human stem cells without using animal substances

DNAzymes and substrates constitute a platform for logic operations essential to computational processes

Scientists identify new susceptibility genes in genome-wide association study of nasopharyngeal carcinoma

Researchers identify gene responsible for Meckel-Gruber and Joubert syndromes

Various aspects of consumer genetics to be discussed at 2nd Annual Consumer Genetics Conference

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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