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BGU researchers identify probiotic yogurt-based drug candidates

Researchers at Ben-Gurion University of the Negev (BGU) have for the first time identified new drug candidates based on molecules isolated from probiotic Kefir yogurt for combating pathogenic bacteria and treating various inflammatory conditions, including inflammatory bowel disease (IBD) and COVID-19 related cytokine storms.

12 Apr 2021

Small molecule inhibitors of SARS-CoV-2 identified by screening

A new study describes the identification of small molecule inhibitors that block the catalytic activity of the crucial viral non-structural protein 5 (nsp5), using a large-scale screening method.

12 Apr 2021

Imbalanced bacterial community in the gums linked to Alzheimer's disease biomarker

Older adults with more harmful than healthy bacteria in their gums are more likely to have evidence for amyloid beta--a key biomarker for Alzheimer's disease--in their cerebrospinal fluid (CSF), according to new research from NYU College of Dentistry and Weill Cornell Medicine.

12 Apr 2021

Lung microbiome predicts COVID-19 disease severity

A new preprint research paper posted to the medRxiv* server found changes to the lung microbiome during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection influence COVID-19 disease severity.

12 Apr 2021

Novel protein transport system mediates toxin secretion by tuberculosis pathogen

Six years ago, Michael Niederweis, Ph.D., described the first toxin ever found for the deadly pathogen Mycobacterium tuberculosis.

9 Apr 2021

Study reveals molecular mechanisms of drug resistance in Mycobacterium tuberculosis

A consortium of researchers from Russia, Belarus, Japan, Germany and France led by a Skoltech scientist have uncovered the way in which Mycobacterium tuberculosis survives in iron-deficient conditions by utilizing rubredoxin B, a protein from a rubredoxin family that play an important role in adaptation to changing environmental conditions.

9 Apr 2021

Purdue researchers use malaria expertise to track COVID-19 in Indiana

Scientists have been using genetics to track diseases for decades. Now, a team at Purdue University that typically tracks malaria spread in Southern and Central Africa is using its expertise to track COVID-19 in Indiana.

8 Apr 2021

Leaky gut and microbial dysbiosis could contribute to cytokine storm in severely ill COVID-19 cases

The gut is a well-established route of infection and target for viral damage by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for COVID-19. This is supported by the clinical observation that about half of COVID-19 patients exhibit gastrointestinal (GI) symptoms.

8 Apr 2021

Unique fungal environment in the lungs

The lungs were for a long time considered to be sterile in health, while in diseases like chronic obstructive pulmonary disease (COPD) failure in immune mechanisms were thought to allow microorganisms to proliferate and persist.

7 Apr 2021

New test for Lyme disease can reliably distinguish between early- and late-stage patients

For those who live in an area blighted by ticks, the threat of Lyme disease can cast a shadow over the joy of spring and summer.

7 Apr 2021

$15.7 million NIMH grant to renew UC Davis Conte Center studying the origins of mental illness

Discovering how infections during pregnancy, such as COVID-19 and influenza, can lead to psychiatric illness and developmental disorders in offspring years later, and how to detect, prevent or treat these disorders, is the subject of a $15.7 million grant from the National Institute of Mental Health to the Conte Center at the University of California, Davis.

7 Apr 2021

Gut microbiome communicates with horse’s cells to enhance their athletic performance

A horse’s gut microbiome communicates with its host by sending chemical signals to its cells, which has the effect of helping the horse to extend its energy output, finds a new study published in Frontiers in Molecular Biosciences.

7 Apr 2021

Researchers explore link between intestinal microbiota with colon cancer in patients with Lynch Syndrome

The researcher Gabriela Debesa, member of the research group at Simbiosis led by Andrés Moya at the Foundation for the Promotion of Health and Biomedical Research of Valencia Region (Fisabio), studied the relationship of the intestinal microbiota with colon cancer in patients with Lynch Syndrome (a hereditary illness that predisposes the development of cancer) using tissue samples in formalin and conserved in paraffin.

6 Apr 2021

Discovering DNA methylation from bacteria and microbiome using nanopore technology

Bacterial DNA methylation occurs at diverse sequence contexts and plays important functional roles in cellular defense and gene regulation. An increasing number of studies have reported that bacterial DNA methylation has important roles affecting clinically relevant phenotypes such as virulence, host colonization, sporulation, biofilm formation, among others.

5 Apr 2021

FDA investigates contributing factors for reported infections from reprocessed urological endoscopes

Today, the U.S. Food and Drug Administration announced it is investigating numerous medical device reports (MDRs) describing patient infections and other possible contamination issues associated with reprocessing urological endoscopes, including cystoscopes, ureteroscopes and cystourethroscopes—devices used to view and access the urinary tract.

1 Apr 2021

Study shows how early life sugar consumption may lead to impaired memory in adulthood

New research shows how drinking sugary beverages early in life may lead to impaired memory in adulthood. The study, published today in Translational Psychiatry, also is the first to show how a specific change to the gut microbiome -- the bacteria and other microorganisms growing in the stomach and intestines -- can alter the function of a particular region of the brain.

31 Mar 2021

Bacterial News and Research

BGU researchers identify probiotic yogurt-based drug candidates

Small molecule inhibitors of SARS-CoV-2 identified by screening

Imbalanced bacterial community in the gums linked to Alzheimer's disease biomarker

Lung microbiome predicts COVID-19 disease severity

Novel protein transport system mediates toxin secretion by tuberculosis pathogen

Study reveals molecular mechanisms of drug resistance in Mycobacterium tuberculosis

Purdue researchers use malaria expertise to track COVID-19 in Indiana

Leaky gut and microbial dysbiosis could contribute to cytokine storm in severely ill COVID-19 cases

Unique fungal environment in the lungs

New test for Lyme disease can reliably distinguish between early- and late-stage patients

$15.7 million NIMH grant to renew UC Davis Conte Center studying the origins of mental illness

Gut microbiome communicates with horse’s cells to enhance their athletic performance

Researchers explore link between intestinal microbiota with colon cancer in patients with Lynch Syndrome

Discovering DNA methylation from bacteria and microbiome using nanopore technology

FDA investigates contributing factors for reported infections from reprocessed urological endoscopes

Study shows how early life sugar consumption may lead to impaired memory in adulthood

Scientists discover how Streptococcus pyogenes can obtain nutrition from the skin surface

Male fetuses impair the maternal and placental immune response to SARS-CoV-2 infection in pregnancy, finds study

Widely available drug reduces morbidity, mortality in COVID-19-infected mice

Protein could be key to blocking the most common bacterial cause of food poisoning

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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