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Roundup: Larger-than-expected Medicaid enrollment in Conn.; Texas bill renews rural abortion debate; Calif. details exchange self-sufficiency

Ron Harney is still looking for work after being laid off from his marketing firm job three years ago. He's used up nearly all of his savings and says he's grateful for the state's Medicaid program, which covers the medical care he needs to manage his HIV.

20 Nov 2012

Nasal spray sufficient for allergic rhinitis in Japanese patients

Intranasal corticosteroid sprays can be administered as a first-line treatment for Japanese patients with seasonal allergic rhinitis, without the need to use systemic corticosteroid drugs, suggest study findings.

20 Nov 2012

Pediatric TB under-diagnosed, treated, MSF report says

According to a new report released by Medecins Sans Frontieres (MSF) at the Union World Conference on Lung Health in Kuala Lumpur, many tuberculosis (TB) programs "under-diagnose, under-treat or completely leave children with TB out, despite the increase in pediatric TB, and rising numbers of children who are infected with drug-resistant forms of TB strains," PlusNews reports.

20 Nov 2012

Injured patients with high blood alcohol levels less likely to die in hospitals

Injured patients were less likely to die in the hospital if they had alcohol in their blood, according to a study from the University of Illinois at Chicago School of Public Health -- and the more alcohol, the more likely they were to survive.

20 Nov 2012

Aradigm’s Lipoquin provides full protection in murine models of pneumonic plague

Scientists from the UK Defence Science and Technology Laboratory (Dstl) report, in a preliminary study, that they have demonstrated that a single dose of Aradigm Corporation's liposomal ciprofloxacin formulation Lipoquin administered 24 hours after exposure to a lethal dose of the bacterium Yersinia pestis provided full protection in a murine model of pneumonic plague.

20 Nov 2012

IL-13 receptor system could play a major role in Parkinson's

Deciphering what causes the brain cell degeneration of Parkinson's disease has remained a perplexing challenge for scientists. But a team led by scientists from The Scripps Research Institute (TSRI) has pinpointed a key factor controlling damage to brain cells in a mouse model of Parkinson's disease.

20 Nov 2012

Drug shortages a new way of life in providing care; Lawmakers call for investigation

As health care facilities struggle to keep inventories of key medicines, some are resorting to risky practices. Meanwhile, six members of Congress seek GAO probe of pharmaceutical contracting so see if it has hurt generic drugmakers and added to shortages.

20 Nov 2012

Inspiration, Ipsen receive FDA Fast Track designation for OBI-1 to treat AHA

Ipsen and Inspiration Biopharmaceuticals Inc. today announced that Inspiration has received Fast Track designation from the US Food and Drug Administration (FDA) for OBI-1 in acquired hemophilia A.

20 Nov 2012

$Digital X-ray radiogrammetry can help identify patients with increased risk of hip fracture$

Digital X-ray radiogrammetry can help identify patients with increased risk of hip fracture

A new study from Karolinska Institutet in Sweden shows, that a technique for measuring bone density called digital X-ray radiogrammetry (or DXR) used on standard hand radiographs can help to identify patients with a higher risk of hip fracture.

20 Nov 2012

Finnish researchers develop triumphant solution to predict breast cancer cells’ responses to drugs

The answer is yes. Finnish researchers have developed a triumphant solution for predicting responses of breast cancer cells to a set of cancer drugs. The prediction is based on the genomic profiles of the cancer cells. Harnessing genomic profiles of cells in choosing the best treatment is considered the holy grail of personalised medicine.

20 Nov 2012

KLF4 genetic factor prevents blood vessels from blockages

Researchers at Case Western Reserve University School of Medicine have identified a genetic factor that prevents blockages from forming in blood vessels, a discovery that could lead to new therapies for cardiovascular diseases.

20 Nov 2012

CFFT announces major expansion of research collaboration with Pfizer

Cystic Fibrosis Foundation Therapeutics Inc. (CFFT), the nonprofit drug discovery and development affiliate of the Cystic Fibrosis Foundation, today announced a major expansion of its research collaboration with Pfizer Inc. designed to discover new drugs to treat people with the most common mutation of CF, Delta F508.

20 Nov 2012

New fiber-optic device can deliver light to the brain in 3D

A new tool for neuroscientists delivers a thousand pinpricks of light to a chunk of gray matter smaller than a sugar cube. The new fiber-optic device, created by biologists and engineers at the Massachusetts Institute of Technology (MIT) in Cambridge, is the first tool that can deliver precise points of light to a 3-D section of living brain tissue. The work is a step forward for a relatively new but promising technique that uses gene therapy to turn individual brain cells on and off with light.

19 Nov 2012

Viewpoints: 'Bad idea' about repealing Medicare cost board; Conservatives say health law repeal fight is not over

House Republicans like to talk about the need to find common ground with President Obama to make progress on important national issues, especially after the election. Yet within days, they were setting an agenda to eliminate an important element of his signature domestic achievement, the Affordable Care Act.

19 Nov 2012

Treatment-related heart failure risk for rheumatoid arthritis patients revealed

Rheumatoid arthritis patients have no greater risk for heart failure with tumor necrosis factor-alpha therapy than with nonbiologic disease-modifying antirheumatic drugs, research suggests.

19 Nov 2012

Two equally effective TNF inhibitors in rheumatoid arthritis

Adalimumab and etanercept are equally effective as tumor necrosis factor inhibitors in the treatment of patients with active rheumatoid arthritis, report researchers.

19 Nov 2012

Biomolecular imaging: an interview with Professor Roger Reddel

The reason Children’s Medical Research Institute (CMRI) exists is to find ways to treat or prevent childhood disease. Our research programs are focussed on the areas of cancer cell growth, nerve cell signalling, embryology and gene therapy. These four programs have a shared aim of translating novel findings into new treatments for the benefit of families everywhere.

19 Nov 2012

New €6 million European project to address complications associated with diabetes

NUI Galway has been awarded a major new €6 million European project, designed to address complications associated with diabetes. The research project will examine the ability of stem cells to safely control glucose levels and alleviate the damage caused by six different diabetic complications.

19 Nov 2012

EMUC discusses current and future prospects in imaging for prostate cancer

At the 4th European Multidisciplinary Meeting on Urological Cancers (EMUC) held this weekend in Barcelona, Spain, specialists from radiology, urology, medical oncology and pathology said that new developments and research are already underway but benefits to patients would take some time due to the need for clinical trials, the high cost of funding research and the ability of cancer experts to efficiently take advantage of new insights and approaches, among other challenges.

19 Nov 2012

Zolpidem associated with increased risk of falls

A drug commonly prescribed to help patients sleep in hospitals has been associated with an increased risk of falls, according to a study published in the Journal of Hospital Medicine.

19 Nov 2012