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Induced-pluripotent stem cells not as genetically unstable as previously thought

Stanford University School of Medicine scientists have demonstrated, in a study conducted jointly with researchers at Yale University, that induced-pluripotent stem cells - the embryonic-stem-cell lookalikes whose discovery a few years ago won this year's Nobel Prize in medicine - are not as genetically unstable as was thought.

19 Nov 2012

NIH-funded scientists develop new treatment to combat autoimmune disorders in mouse model

In a mouse model of multiple sclerosis (MS), researchers funded by the National Institutes of Health have developed innovative technology to selectively inhibit the part of the immune system responsible for attacking myelin-the insulating material that encases nerve fibers and facilitates electrical communication between brain cells.

18 Nov 2012

Summit looks at the growing problem of prescription drug abuse

Today, a not-for-profit organization presenting at the Delaware Prescription Drug Abuse Summit appealed to the event's host, Attorney General Beau Biden, for assistance in preventing medication overdoses.

17 Nov 2012

United States Pharmacopeial Convention to host Fifth Bioassay Workshop in Rockville

As a growing number of biologic drugs are treatments of choice for an expanding list of autoimmune disorders, inflammatory diseases, and certain cancers, bioassays play a critical role in establishing the functional integrity and potency of these products.

17 Nov 2012

MusculoskeletalNetwork features special coverage of sessions from ACR annual meeting

UBM Medica US announces that MusculoskeletalNetwork features special coverage of sessions from the annual meeting of the American College of Rheumatology (ACR), including the latest information about new FDA processes for approval of biosimilars that are like generic versions of expensive medications now used to treat painful rheumatologic conditions such as rheumatoid arthritis (RA).

17 Nov 2012

Personality traits linked with individual's susceptibility to placebo effect from pain medicines

Personality traits might do more than help you win a popularity contest. According to new University of Michigan-led neuroscience research, co-authored by University of Maryland (UM) School of Dentistry Dean Christian S. Stohler, DMD, DrMedDent, such traits also might make you more likely to get pain relief from a placebo - a fake medicine.

17 Nov 2012

Research roundup: Talking to patients about end-of-life care

Each week, KHN reporter Alvin Tran compiles a selection of recently released health policy studies and briefs.

17 Nov 2012

HCV medications' side effects can now be replicated and observed in Petri dishes and test tubes

The adverse side effects of certain hepatitis C medications can now be replicated and observed in Petri dishes and test tubes, thanks to a research team led by Craig Cameron, the Paul Berg Professor of Biochemistry and Molecular Biology at Penn State University.

17 Nov 2012

Global Fund Board announces integration of AMFm into core grant system

The Board of the Global Fund to Fight AIDS, Tuberculosis and Malaria on Thursday announced it will "integrate" the Affordable Medicines Facility-malaria (AMFm), implemented in 2010 as a pilot program to provide low-cost artemisinin-based combination therapies (ACTs) in poor and rural areas, "into its existing core system of providing grants to countries to purchase drugs, bed nets and other malaria-control measures," Nature News Blog reports.

17 Nov 2012

Cancer Network, ONCOLOGY present two part primer report on targeted therapies in solid tumors

UBM Medica US announces that Cancer Network and the journal ONCOLOGY are presenting a two part primer report on targeted therapies in solid tumors.

17 Nov 2012

Researchers analyze Brazilian mediums' cerebral blood flow during practice of psychography

Researchers at Thomas Jefferson University and the University of Sao Paulo in Brazil analyzed the cerebral blood flow (CBF) of Brazilian mediums during the practice of psychography, described as a form of writing whereby a deceased person or spirit is believed to write through the medium's hand.

17 Nov 2012

Cinacalcet failure raises trial conduct issues

The oral calcimimetic agent, cinacalcet, has been found to have no significant effect on cardiovascular events or death in patients with chronic kidney disease in a randomized controlled trial.

16 Nov 2012

Caterpillar fungi may benefit asthma patients

Research shows that cordycepin, extracted from a group of rare parasitic caterpillar fungi of the genus Cordyceps, has unusual anti-inflammatory properties that may make it a good candidate for treating conditions such as asthma and rheumatoid arthritis.

16 Nov 2012

Experts call for global treaty on drug quality

Professionals from the world of health, including health charities, legal and medical academia, and former or current government health officials, have called for the creation of an internationally binding treaty to tackle illegitimate drugs.

16 Nov 2012

Shear thinning hydrogels hold promise in treating many diseases, including cancer

Gels that can be injected into the body, carrying drugs or cells that regenerate damaged tissue, hold promise for treating many types of disease, including cancer. However, these injectable gels don't always maintain their solid structure once inside the body.

16 Nov 2012

D737 compound restores motor function and longevity in fruit flies with Alzheimer's

An efficient, high-volume technique for testing potential drug treatments for Alzheimer's disease uncovered an organic compound that restored motor function and longevity to fruit flies with the disease, according to new research that could help put the search for an effective Alzheimer's drug on a faster track.

16 Nov 2012

High risk CVD patients more likely to receive prescriptions for cholesterol-lowering drugs

In a new study, Northwestern Medicine researchers found that patients at high risk for cardiovascular disease (CVD) are more likely to receive a prescription for cholesterol-lowering medication, and to achieve lower long-term cholesterol levels, when doctors use electronic health records (EHRs) to deliver personalized risk assessments via mail.

16 Nov 2012

Positive results from POZEN’s PA8140-102 Phase 1 bioavailability study

POZEN Inc., a pharmaceutical company committed to transforming medicine that transforms lives, announced today that the results from a Phase 1 study, PA8140-102, demonstrated that PA8140, POZEN's proprietary combination of aspirin (81 mg) and omeprazole (40 mg), had comparable bioavailability relative to the reference listed product, enteric-coated (EC) aspirin (81 mg).

16 Nov 2012

Longer looks: A dentist tries to clear his debt; Bringing mental health services to the marines; Learning to laugh in the doctor's office

His jaw clenched beneath a blue surgeon's mask, Opanin Gyaami jerks his right arm and pulls out a prize: the decayed tooth of patient Larry Butler, also known as state prison inmate J22312. By the time he is done, Gyaami's smock and mask are spotted with the inmate's blood. He gently pats Butler on the shoulder and wishes him well.

16 Nov 2012

Researchers discover unlikely recipe to kill antibiotic resistant bacteria

Washington State University researchers have found an unlikely recipe for antibiotic resistant bacteria: Mix cow dung and soil, and add urine infused with metabolized antibiotic. The urine will kill off normal E. coli in the dung-soil mixture. But antibiotic-resistant E. coli will survive in the soil to recolonize in a cow's gut through pasture, forage or bedding.

16 Nov 2012

Drugs News and Research

Induced-pluripotent stem cells not as genetically unstable as previously thought

NIH-funded scientists develop new treatment to combat autoimmune disorders in mouse model

Summit looks at the growing problem of prescription drug abuse

United States Pharmacopeial Convention to host Fifth Bioassay Workshop in Rockville

MusculoskeletalNetwork features special coverage of sessions from ACR annual meeting

Personality traits linked with individual's susceptibility to placebo effect from pain medicines

Research roundup: Talking to patients about end-of-life care

HCV medications' side effects can now be replicated and observed in Petri dishes and test tubes

Global Fund Board announces integration of AMFm into core grant system

Cancer Network, ONCOLOGY present two part primer report on targeted therapies in solid tumors

Researchers analyze Brazilian mediums' cerebral blood flow during practice of psychography

Cinacalcet failure raises trial conduct issues

Caterpillar fungi may benefit asthma patients

Experts call for global treaty on drug quality

Shear thinning hydrogels hold promise in treating many diseases, including cancer

D737 compound restores motor function and longevity in fruit flies with Alzheimer's

High risk CVD patients more likely to receive prescriptions for cholesterol-lowering drugs

Positive results from POZEN’s PA8140-102 Phase 1 bioavailability study

Longer looks: A dentist tries to clear his debt; Bringing mental health services to the marines; Learning to laugh in the doctor's office

Researchers discover unlikely recipe to kill antibiotic resistant bacteria

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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