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A peek at Big Pharma’s playbook that leaves many Americans unable to afford their drugs

America's pharmaceutical giants are suing this summer to block the federal government's first effort at drug price regulation.

18 Aug 2023

A new Medicare proposal would cover training for family caregivers

Even with extensive caregiving experience, Patti LaFleur was unprepared for the crisis that hit in April 2021, when her mother, Linda LaTurner, fell out of a chair and broke her hip.

18 Aug 2023

Can your screen time affect your bowel movements?

The causal relationship between leisure screen time and irritable bowel syndrome.

18 Aug 2023

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Researchers describe molecular signalling regulated by mTOR among memory and exhausted cytotoxic CD8+ T lymphocytes.

18 Aug 2023

New study untied taste from smell in people with COVID-19

Smell loss became the cardinal symptom of COVID-19 early in the pandemic and has ignited research on how smell and taste function. An international study led by the Global Consortium for Chemosensory Research (GCCR) and the Monell Chemical Senses Center has untied taste from smell in people with COVID-19, demonstrating in a large and diverse group of more than 10,000 people that taste, independent of smell, is also greatly impacted by COVID. The team recently published their findings in Chemical Senses.

18 Aug 2023

Immune cells present in people months before influenza infection, finds study

St. Jude Children's Research Hospital scientists, in collaboration with the Institute of Environmental Science and Research (ESR) Limited, found that immune cells present in people months before influenza (flu) infection could more accurately predict if an individual would develop symptoms than current methods which primarily rely on antibody levels.

18 Aug 2023

New findings could develop effective vaccines or treatments for chikungunya fever

Researchers at Albert Einstein College of Medicine have found that the virus responsible for chikungunya fever can spread directly from cell to cell - perhaps solving the longstanding mystery of how the virus, now emerging as a major health threat, can manage to escape antibodies circulating in the bloodstream.

18 Aug 2023

Platelets quell the inflammation of an aging brain and body: Study finds

Platelets are behind the cognitive benefits of young blood, exercise and the longevity hormone klotho

18 Aug 2023

Male diabetics more likely to have lower limb amputation

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Hamburg, Germany (2-6 October) shows that among people with type 1 and type 2 diabetes, being divorced is associated with a two-thirds higher risk of lower limb amputation (LLA) (amputations below the knee level) compared with being married, and being male is associated with a 57% higher risk of LLA compared with being female. The study is by Dr Stefan Jansson, Örebro University, Örebro, Sweden, and colleagues.

18 Aug 2023

New method to assess the status of immune responses to specific antigens in detail

A new method to assess the status of immune responses to specific antigens in detail by analysis using the B cell receptor (BCR) repertoire has been developed by a research group, consisting of Assistant Professor Yohei Funakoshi, Associate Professor Kimikazu Yakushijin, Professor Hironobu Minami (Kobe University Graduate School of Medicine), Associate Professor Goh Ohji (Kobe University Hospital), and Researcher Takaji Matsutani (Repertoire Genesis Inc.).

18 Aug 2023

Understanding how the body regulates circadian rhythms using mathematical models

Researchers are using mathematical models to better understand the effects of disruptions like daylight savings time, working night shifts, jet lag or even late-night phone scrolling on the body's circadian rhythms.

18 Aug 2023

FDA approved Rexulti to be the first antipsychotic for treating agitation in elderly patients with dementia

In trials, the antipsychotic drug brexpiprazole (Rexulti) failed to provide a clinically meaningful benefit and increased the risk of death. Yet the US Food and Drug Administration (FDA) has fast tracked its approval, making Rexulti the first antipsychotic for treating agitation in elderly patients with dementia.

18 Aug 2023

New drug candidate nearly doubles survival for patients with aggressive childhood brain tumors

For the first time, researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain tumor for which there are no effective treatments.

17 Aug 2023

WHO updates recommendation for malaria-preventing mosquito nets based on new research

The World Health Organisation (WHO) has updated its recommendation for malaria-preventing mosquito nets based on new research from the University of Adelaide.

17 Aug 2023

Medications for chronic diseases can impair thermoregulation, especially in hot weather

Medications to treat various chronic diseases may hinder the body’s ability to lose heat and regulate its core temperature to optimal levels.

17 Aug 2023

Study opens the door to new treatments for bone regeneration and osteoporosis

A new study of the PhyloBone project of the University of Turku, Finland, identifies hundreds of non-collagenous proteins in the bone matrix that may play regulatory roles in bone formation and regeneration.

17 Aug 2023

Databases, techniques for variant forecasting and early warning of emerging infectious diseases

The coronavirus disease 2019 (COVID-19) pandemic has dramatically increased the awareness of emerging infectious diseases.

17 Aug 2023

Lorazepam linked to shorter progression-free survival in pancreatic cancer patients

Patients with pancreatic cancer who took the benzodiazepine lorazepam (Ativan), commonly prescribed to treat anxiety during cancer treatment, had a shorter progression-free survival than patients who did not, according to results published in Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR).

17 Aug 2023

AI model can detect atrial septal defect in ECGs with high accuracy

The AI model was more efficient at detecting signatures of atrial septal defect (ASD) in electrocardiograms (ECG) than traditional methods.

17 Aug 2023

Astrocytes play major role in controlling sleep need

New animal research suggests that little-studied brain cells known as astrocytes are major players in controlling sleep need and may someday help humans go without sleep for longer without negative consequences such as mental fatigue and impaired physical health.

17 Aug 2023

Research News and Research

A peek at Big Pharma’s playbook that leaves many Americans unable to afford their drugs

A new Medicare proposal would cover training for family caregivers

Can your screen time affect your bowel movements?

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

New study untied taste from smell in people with COVID-19

Immune cells present in people months before influenza infection, finds study

New findings could develop effective vaccines or treatments for chikungunya fever

Platelets quell the inflammation of an aging brain and body: Study finds

Male diabetics more likely to have lower limb amputation

New method to assess the status of immune responses to specific antigens in detail

Understanding how the body regulates circadian rhythms using mathematical models

FDA approved Rexulti to be the first antipsychotic for treating agitation in elderly patients with dementia

New drug candidate nearly doubles survival for patients with aggressive childhood brain tumors

WHO updates recommendation for malaria-preventing mosquito nets based on new research

Medications for chronic diseases can impair thermoregulation, especially in hot weather

Study opens the door to new treatments for bone regeneration and osteoporosis

Databases, techniques for variant forecasting and early warning of emerging infectious diseases

Lorazepam linked to shorter progression-free survival in pancreatic cancer patients

AI model can detect atrial septal defect in ECGs with high accuracy

Astrocytes play major role in controlling sleep need

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