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MED1 plays a central role in mediating tamoxifen resistance in breast cancer

A University of Cincinnati (UC) cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients with estrogen-positive breast cancers, combating a widespread problem in effective medical management of the disease.

3 Nov 2012

WSU researcher receives NSF fund to study on antibiotic resistance

In March, the director-general of the World Health Organization warned of "an end to modern medicine as we know it."

3 Nov 2012

Researchers develop new technique to predict enzymes known to accelerate diseases

Predicting how atherosclerosis, osteoporosis or cancer will progress or respond to drugs in individual patients is difficult.

3 Nov 2012

FDA expands Janssen’s Xarelto use to reduce risk of DVT and PE

The U.S. Food and Drug Administration today expanded the approved use of Xarelto (rivaroxaban) to include treating deep vein thrombosis (DVT) or pulmonary embolism (PE), and to reduce the risk of recurrent DVT and PE following initial treatment.

3 Nov 2012

Study results show ongoing comparison of prescription drug costs between US and UK

In the United States, the cost paid for statins (drugs to lower cholesterol) in people under the age of 65 who have private insurance continues to exceed comparable costs paid by the government in the United Kingdom by more than three fold.

3 Nov 2012

Adding angiogenesis inhibitor to anti-HER2 drugs extends survival in mice with breast cancer

Adding an angiogenesis inhibitor to treatment with a HER2-inhibiting drug could improve outcomes for patients with HER2-positive breast cancer who develop brain metastases. In their report published online in PNAS Plus, Massachusetts General Hospital (MGH) investigators report the first preclinical study combining antiangiogenic and anti-HER2 drugs in an animal model of brain metastatic breast cancer.

3 Nov 2012

Intensified antibiotic treatment can improve prognosis of patients with TB meningitis

Researchers from the Radboud UMC have conducted the first study globally to show that intensified antibiotic treatment can improve the prognosis of patients with tuberculous (TB) meningitis, the most severe form of TB which carries a mortality of up to 50%.

3 Nov 2012

Mass spectrometry can help visualize how drugs work inside living cells to kill infectious microbes

Weill Cornell Medical College researchers report that mass spectrometry, a tool currently used to detect and measure proteins and lipids, can also now allow biologists to "see" for the first time exactly how drugs work inside living cells to kill infectious microbes.

3 Nov 2012

Treatments and outcomes vary for nursing home residents who use Medicare SNF care: Study

A Medicare rule that blocks thousands of nursing home residents from receiving simultaneous reimbursement for hospice and skilled nursing facility care at the end of life may result in those residents receiving more aggressive treatment and hospitalization, according a new analysis.

3 Nov 2012

Physicists to bring to market new drug-discovery tool using genetic sequencing

Today physicists at Wake Forest University and NanoMedica, their biotechnology company partner, received a $700,000 grant from the National Institutes of Health to bring to market a new drug-discovery tool using next-generation genetic sequencing.

3 Nov 2012

University of Cambridge forms new spin-out company to supply hIPSC-derived cells

The potential therapeutic applications of stem cells - such as regenerating damaged tissues or organs - have generated a great deal of interest over the past decade. While these types of applications are exciting, it is a long journey from lab to clinic. The most immediate impact of stem cells on human health will most likely come from their use in the development of new drugs.

3 Nov 2012

Abortion, health law drive messaging in tight Senate and House races

The state Democratic Party runs a "coordinated campaign" to augment the Obama team's efforts and promote Mr. Kaine and other Democratic candidates, with hubs in Alexandria, a Washington suburb; Richmond, the capital; the Hampton Roads area, a military center; and Charlottesville, a student bastion.

3 Nov 2012

Advanced breast cancer that has spread to the brain could be treated with drug combination

The sizeable and increasing proportion of women with advanced breast cancer whose disease has spread to the brain could be effectively treated systemically with a combination of two drugs, sparing them the debilitating neurological side effects of whole brain radiotherapy (WBRT), suggests new research published Online First in The Lancet Oncology.

2 Nov 2012

Imatinib mesylate effectively treats children with neurofibromatosis type 1 tumors

Physician-researchers at Indiana University School of Medicine have reported the first effective therapy for a class of previously untreatable and potentially life-threatening tumors often found in children.

2 Nov 2012

Compounding pharmacies rarely get tough punishments; Another firm recalls drugs

USA Today examines how officials have dealt with charges of misconduct at the pharmacies in the past. Meanwhile, a compounding pharmacy, which is owned by the same company that owned the plant linked to the meningitis outbreak, is recalling its products after an FDA review.

2 Nov 2012

CD22 protein could prove to be important new target for anti-cancer therapy

A team of UC Davis investigators has discovered a protein on the surface of lung cancer cells that could prove to be an important new target for anti-cancer therapy. A series of experiments in mice with lung cancer showed that specific targeting of the protein with monoclonal antibodies reduced the size of tumors, lowered the occurrence of metastases and substantially lengthened survival time.

2 Nov 2012

MH6 vaccine shows promise in treating meth addiction

Scientists at The Scripps Research Institute (TSRI) have performed successful tests of an experimental methamphetamine vaccine on rats. Vaccinated animals that received the drug were largely protected from typical signs of meth intoxication.

2 Nov 2012

Antipsychotic drugs associated with increased mortality among people with schizophrenia

Results of a Johns Hopkins study suggest that individuals with schizophrenia are significantly more likely to live longer if they take their antipsychotic drugs on schedule, avoid extremely high doses and also regularly see a mental health professional.

2 Nov 2012

NIH grant increases support of SDSU program that prepares students for doctoral and science careers

Funded by a $2.8 million grant from the National Institutes of Health and the National Institute of General Medical Sciences, the Initiative for Maximizing Student Development supports 30 students studying in the fields of biomedical and behavioral sciences.

2 Nov 2012

Study identifies monoacylglycerol lipase as new therapeutic target to treat Alzheimer's

Research led by Chu Chen, PhD, Associate Professor of Neuroscience at LSU Health Sciences Center New Orleans, has identified an enzyme called Monoacylglycerol lipase (MAGL) as a new therapeutic target to treat or prevent Alzheimer's disease.

2 Nov 2012

Drugs News and Research

MED1 plays a central role in mediating tamoxifen resistance in breast cancer

WSU researcher receives NSF fund to study on antibiotic resistance

Researchers develop new technique to predict enzymes known to accelerate diseases

FDA expands Janssen’s Xarelto use to reduce risk of DVT and PE

Study results show ongoing comparison of prescription drug costs between US and UK

Adding angiogenesis inhibitor to anti-HER2 drugs extends survival in mice with breast cancer

Intensified antibiotic treatment can improve prognosis of patients with TB meningitis

Mass spectrometry can help visualize how drugs work inside living cells to kill infectious microbes

Treatments and outcomes vary for nursing home residents who use Medicare SNF care: Study

Physicists to bring to market new drug-discovery tool using genetic sequencing

University of Cambridge forms new spin-out company to supply hIPSC-derived cells

Abortion, health law drive messaging in tight Senate and House races

Advanced breast cancer that has spread to the brain could be treated with drug combination

Imatinib mesylate effectively treats children with neurofibromatosis type 1 tumors

Compounding pharmacies rarely get tough punishments; Another firm recalls drugs

CD22 protein could prove to be important new target for anti-cancer therapy

MH6 vaccine shows promise in treating meth addiction

Antipsychotic drugs associated with increased mortality among people with schizophrenia

NIH grant increases support of SDSU program that prepares students for doctoral and science careers

Study identifies monoacylglycerol lipase as new therapeutic target to treat Alzheimer's

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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