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Short-course palliative RT shows promise

A 2-day course of three-dimensional radiotherapy delivered in twice-daily fractions up to 18 Gy resulted in no dose-limiting toxicities, and high rates of symptom relief in patient with pelvic cancer, especially those with bleeding, report researchers.

26 Jul 2012

Study uses photodynamic therapy to ablate cardiac myocytes responsible for arrhythmias

University of Michigan heart researchers are shedding light on a safer method for steadying an abnormal heart rhythm that prevents collateral damage to healthy cells.

25 Jul 2012

Latest polypill trial yields largest improvements yet

The results of the first trial to administer the polypill on the basis of age alone has shown the largest reductions in blood pressure and cholesterol level of any polypill trial to date, researchers report.

24 Jul 2012

Findings cast doubt on sepsis drug withdrawal

A meta-analysis of clinical trial and real-world data suggests that drotrecogin alfa may in fact reduce mortality in patients with severe sepsis.

24 Jul 2012

Coagulation history ‘should be taken before tonsillectomy’

Adults scheduled for tonsillectomy should be asked about their coagulation history before the procedure, researchers warn.

24 Jul 2012

PAMAM G-3 actually prevents activation of the process that leads to thrombosis

A compound that mops up debris of damaged cells from the bloodstream may be the first in a new class of drugs designed to address one of medicine's most difficult challenges -- stopping the formation of blood clots without triggering equally threatening bleeding.

24 Jul 2012

HAS-BLED: Atrial fibrillation patients undergoing angioplasty can still take anticoagulants

Researchers say that oral anticoagulation could improve the prognosis of atrial fibrillation patients who undergo percutaneous coronary intervention, even if they have a high bleeding risk according to the HAS-BLED score.

19 Jul 2012

Proton pump inhibitors for clopidogrel patients ‘not so dangerous’

The interaction between proton pump inhibitors and clopidogrel is “clinically unimportant,” say researchers in the BMJ.

19 Jul 2012

Study gauges depression among spouses of severe-sepsis survivors

Severe sepsis, a body's dangerous defensive response against an infection, not only diminishes the quality of life for patients - it puts their spouses at a greater risk of depression, a joint University of Michigan Health System and University of Washington School of Medicine study shows.

19 Jul 2012

Positive preliminary results from Feraheme phase III study on iron deficiency anemia

AMAG Pharmaceuticals, Inc. today reported preliminary results from the second phase III study from its global registrational program for Feraheme (ferumoxytol) in patients with iron deficiency anemia (IDA) regardless of the underlying cause.

19 Jul 2012

Combination of tPA and 3K3A-APC may effectively treat stroke

A team led by a physician-scientist at the University of Southern California (USC) has created an experimental drug that reduces brain damage and improves motor skills among stroke-afflicted rodents when given with federally approved clot-busting therapy.

18 Jul 2012

Smoking, hepatitis and liver transplantation: An interview with Dr Peter Ghali

We are very interested in hepatitis C as it is the most common indication for liver transplant in the Western world. The difficulty is that recurrence happens in the majority of patients within the first 2 to 7 years after transplant, and occasionally sooner.

18 Jul 2012

Johnson & Johnson second quarter sales decrease 0.7% to $16.5B

Johnson & Johnson today announced sales of $16.5 billion for the second quarter of 2012, a decrease of 0.7% as compared to the second quarter of 2011. Operational results increased 3.5% and the negative impact of currency was 4.2%.

17 Jul 2012

VHVI now offers new minimally invasive, catheter-based approach to dissolve pulmonary embolism

The Vanderbilt Heart and Vascular Institute (VHVI) now offers a minimally invasive, catheter-based approach to dissolving pulmonary embolism, a potentially life-threatening blood clot that form elsewhere in the body and travels into the lungs.

17 Jul 2012

SLU professor to study how antithrombin might prevent premature death from heart disease

Alireza "Ray" Rezaie, Ph.D., professor of biochemistry and molecular biology at Saint Louis University School of Medicine, has received a $1.52 million NIH grant to study how the key blood clotting inhibitor antithrombin might be exploited to prevent premature death from heart disease.

12 Jul 2012