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Spike-induced humoral immunity and its association with antibody-dependent cellular cytotoxicity potency

A new study aimed to analyze the qualitative and quantitative impact of S-induced humoral immunity along with its ADCC capability in individuals who received a vaccination, recovered from an infection, or both.

14 Mar 2023

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Researchers investigated whether mRNA technology-based COVID-19 vaccines promote the development of autoantibodies.

14 Mar 2023

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of host-directed broad-acting SARS-CoV-2 therapeutic targets.

14 Mar 2023

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

Researchers assessed the impact of the gut microbiome on the host's bile acid metabolism and intrahepatic cholestasis of pregnancy (ICP).

14 Mar 2023

What is the influence of prenatal second-hand smoke exposure on infant self-regulation?

A new study aimed to analyze an important gap concerning the impact of prenatal SHS exposure on infant self-regulation.

14 Mar 2023

Oral host responses to SARS-CoV-2 predict progression of COVID-19

In a recent study posted to the medRxiv* preprint server, researchers at the University of North Carolina and the National Institutes of Health determined the associations between oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), oral antibodies against SARS-CoV-2, and coronavirus disease 2019 (COVID-19) symptoms.

14 Mar 2023

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus.

14 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.

14 Mar 2023

AI-assisted analysis helps find new targets for CAR-T cell therapy against acute myeloid leukemia

Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy.

13 Mar 2023

No increased risk of neuropsychiatric events in children born to mothers using leukotriene-receptor antagonists in pregnancy

A new study examined the associations between leukotriene-receptor antagonists (LTRAs) use in pregnancy and neuropsychiatric events (NEs) risk in the offspring.

13 Mar 2023

How does temperature affect host responses to SARS-CoV-2 and IAV infection in human nasal epithelial cells?

A new preprint examines the response to these pathogens in the nose, which is the primary portal of entry for both.

13 Mar 2023

Remote hypertension program helped patients to manage blood pressure during the pandemic

Hypertension is the leading risk factor for death worldwide. During the COVID-19 pandemic, routine blood pressure assessments decreased because of global disruptions to medical care delivery.

13 Mar 2023

Components of the gut microbiome could be used to better predict efficacy of CAR-T cell therapy

Even though, according to recent preliminary studies, the risk of dying from cancer has declined within the European Union in recent years, cancers remain among the leading causes of death.

13 Mar 2023

Research reveals the mechanism that triggers breast cancer 'time bomb'

Scientists have discovered why breast cancer cells that have spread to the lungs may 'wake up' following years of sleep - forming incurable secondary tumors.

13 Mar 2023

Exploring airway-to-brain sensory pathways in influenza-induced illness

In a recent study published in the Nature journal, researchers assessed the role of the airway-to-brain sensory pathways in influenza-induced illness.

13 Mar 2023

Bitter taste receptors are a potential target for treating asthma or COPD

Surprisingly, bitter taste receptors are not only located in the mouth, but also elsewhere in the body, including the airways.

13 Mar 2023

Injectable peptide used for type 2 diabetes shows potential for treating 'blinding' IIH headaches

Patients with 'blinding' headaches known as Idiopathic Intercranial Hypertension could be treated with an injectable peptide used for type 2 diabetes, a new trial has found.

13 Mar 2023

Abnormally low autoantibody activity significantly associated with autism severity

A recent study hypothesized a dysfunction of the self-recognition properties of the immune system in autism.

13 Mar 2023

Scientists discover how tendons and salivary glands develop in the jaw

A USC-led team of scientists has made a drool-worthy discovery about how tendons and salivary glands develop in the jaw.

10 Mar 2023

Study creates a radical new view of how immune cells recognize threats

Researchers have created a radical new view of how immune cells recognise threats such as viruses. The discovery could be used to design better vaccines and to gain a deeper insight into autoimmune diseases and allergies.

10 Mar 2023

Receptor News and Research

Spike-induced humoral immunity and its association with antibody-dependent cellular cytotoxicity potency

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

What is the influence of prenatal second-hand smoke exposure on infant self-regulation?

Oral host responses to SARS-CoV-2 predict progression of COVID-19

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

AI-assisted analysis helps find new targets for CAR-T cell therapy against acute myeloid leukemia

No increased risk of neuropsychiatric events in children born to mothers using leukotriene-receptor antagonists in pregnancy

How does temperature affect host responses to SARS-CoV-2 and IAV infection in human nasal epithelial cells?

Remote hypertension program helped patients to manage blood pressure during the pandemic

Components of the gut microbiome could be used to better predict efficacy of CAR-T cell therapy

Research reveals the mechanism that triggers breast cancer 'time bomb'

Exploring airway-to-brain sensory pathways in influenza-induced illness

Bitter taste receptors are a potential target for treating asthma or COPD

Injectable peptide used for type 2 diabetes shows potential for treating 'blinding' IIH headaches

Abnormally low autoantibody activity significantly associated with autism severity

Scientists discover how tendons and salivary glands develop in the jaw

Study creates a radical new view of how immune cells recognize threats

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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