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Preeclampsia risk higher for women with Lupus

New research reports that women with systemic lupus erythematosus (SLE) have a two-fold increase in risk of preeclampsia—a dangerous condition in which pregnant women develop high blood pressure (hypertension) and protein in their urine (proteinuria) after 20 weeks of gestation

30 Oct 2012

Complix to accelerate development of CPABs against intracellular disease targets

Complix announces that it has been awarded a €1.9 million grant (approximately USD$2.4 million) from the Flanders government through IWT (Agency for Innovation by Science and Technology in Flanders).

30 Oct 2012

STAT3 transcription factor remains in the axon of nerve cells to help prevent neurodegeneration

A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow nerve damage in patients with neurodegenerative diseases.

30 Oct 2012

BioXpress, AET BioTech enter agreement to co-develop Adalimumab biosimilar

AET BioTech, the separate biosimilars business within the generic drug developer AET (Alfred E Tiefenbacher) Group and BioXpress Therapeutics SA, a Swiss-based biotechnology company developing monoclonal antibody (MAb) biosimilars have entered into an agreement for the co-development of a biosimilar version of the TNF inhibitor MAb Adalimumab.

30 Oct 2012

Study suggests 2004 lawsuit fueled big spending on epilepsy drugs

In 2004, Pfizer, the world's largest drug company, agreed to plead guilty and pay more than $430 million to settle charges it had illegally marketed the epilepsy drug Neurontin for unapproved uses.

30 Oct 2012

State roundup: Hurricane Sandy has east coast hospitals scrambling

Healthcare providers on the East Coast have spent the weekend preparing for Hurricane Sandy, with hospitals canceling elective surgeries and discharging patients to free up beds.

30 Oct 2012

Romney's vow to repeal health law will be hard to realize; Administration sets up national health plans

Political Pro examines the challenges the GOP presidential nominee would face to dismantle the health law, while the New York Times looks at the government's efforts to set up the nationwide plans mandated by the law.

30 Oct 2012

Viewpoints: Friedman on why Democrats are really the 'pro-life' party; Myths about doctor-assisted suicide

Hard-line conservatives have gone to new extremes lately in opposing abortion. ... These are the authentic voices of an ever-more-assertive far-right Republican base that is intent on using uncompromising positions on abortion to not only unseat more centrist Republicans ... but to overturn the mainstream consensus in America on this issue.

30 Oct 2012

Adolescent males at increased risk of reporting longtime OTC drug use

As crackdowns get tougher on alcohol, tobacco sales, and illicit drugs, there's a growing trend among youth to turn to another source to get a high: their parent's medicine cabinet. A new University of Cincinnati study suggests adolescent males are at a higher risk of reporting longtime use of over-the-counter drugs, compared with their female peers.

30 Oct 2012

IPSCs may be a viable source of patient-specific articular cartilage tissue

A team of Duke Medicine researchers has engineered cartilage from induced pluripotent stem cells that were successfully grown and sorted for use in tissue repair and studies into cartilage injury and osteoarthritis.

30 Oct 2012

Researchers decode software instructions that drive 3 different forms of acute lymphoblastic leukemia

30 Oct 2012

Array BioPharma first quarter 2013 revenue decreases to $15.8 million

Array BioPharma Inc. today reported results for the first quarter of its fiscal year ending June 30, 2013.

30 Oct 2012

Canadian Cardiovascular Society issues new pediatric heart failure guidelines

The Canadian Cardiovascular Society is the first in Canada to issue guidelines aimed at helping primary care and emergency physicians, as well as specialists, recognize and manage heart failure in children. The guidelines were released today at the Canadian Cardiovascular Congress.

30 Oct 2012

Complementary and alternative therapy offers self-reported benefits for arthritis patients

Nearly a quarter of patients with rheumatoid arthritis and osteoarthritis used complementary and alternative therapy (CAT) to help manage their condition, according to a study in the November issue of the Journal of Clinical Nursing.

30 Oct 2012

Carotid ultrasound improves risk management in rheumatoid arthritis

A trial of radiofrequency ultrasound in patients with rheumatoid arthritis has shown that carotid intima-media thickness is significantly greater in patients treated only with synthetic therapeutics compared with those who are also taking biologics.

29 Oct 2012

Scientists decode epigenetic programming of three virulent forms of acute lymphoblastic leukemia

A team of national and international researchers, led by Weill Cornell Medical College scientists, have decoded the key "software" instructions that drive three of the most virulent forms of acute lymphoblastic leukemia (ALL). They discovered ALL's "software" is encoded with epigenetic marks, chemical modifications of DNA and surrounding proteins, allowing the research team to identify new potential biomarkers and therapeutic targets.

29 Oct 2012

Isis commences ISIS-FXIRx Phase 2 study in knee replacement surgery patients

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 2 comparator-controlled study evaluating ISIS-FXIRx in patients undergoing knee replacement surgery, also referred to as total knee arthroplasty (TKA).

29 Oct 2012

Sea water strengthens the body against viruses, low defences, bacteria and pathogens

Sea water therapy is a technique of cellular nutrition backed by more than 100 years of clinical use in hospitals, during which numerous studies have demonstrated its beneficial effects on patients' health.

29 Oct 2012

FDA report says pharmacy knew about contamination problems

A federal inspection of a company whose tainted pain medicine has caused one of the worst public health drug disasters since the 1930s found greenish-yellow residue on sterilization equipment, surfaces coated with levels of mold and bacteria that exceeded the company's own environmental limits, and an air-conditioner that was shut off nightly despite the importance of controlling temperature and humidity.

29 Oct 2012

Range of biopharma solutions from Malvern Instruments extended by distribution agreement with Affinity Biosensors

Materials characterization company Malvern Panalytical. (Malvern Panalytical, UK) has signed an exclusive distribution agreement with Affinity Biosensors LLC (Santa Barbara, CA, USA) which will extend the range of solutions that Malvern Panalytical offers to the biopharmaceutical sector.

From Malvern Panalytical 29 Oct 2012

Drugs News and Research

Preeclampsia risk higher for women with Lupus

Complix to accelerate development of CPABs against intracellular disease targets

STAT3 transcription factor remains in the axon of nerve cells to help prevent neurodegeneration

BioXpress, AET BioTech enter agreement to co-develop Adalimumab biosimilar

Study suggests 2004 lawsuit fueled big spending on epilepsy drugs

State roundup: Hurricane Sandy has east coast hospitals scrambling

Romney's vow to repeal health law will be hard to realize; Administration sets up national health plans

Viewpoints: Friedman on why Democrats are really the 'pro-life' party; Myths about doctor-assisted suicide

Adolescent males at increased risk of reporting longtime OTC drug use

IPSCs may be a viable source of patient-specific articular cartilage tissue

Researchers decode software instructions that drive 3 different forms of acute lymphoblastic leukemia

Array BioPharma first quarter 2013 revenue decreases to $15.8 million

Canadian Cardiovascular Society issues new pediatric heart failure guidelines

Complementary and alternative therapy offers self-reported benefits for arthritis patients

Carotid ultrasound improves risk management in rheumatoid arthritis

Scientists decode epigenetic programming of three virulent forms of acute lymphoblastic leukemia

Isis commences ISIS-FXIRx Phase 2 study in knee replacement surgery patients

Sea water strengthens the body against viruses, low defences, bacteria and pathogens

FDA report says pharmacy knew about contamination problems

Range of biopharma solutions from Malvern Instruments extended by distribution agreement with Affinity Biosensors

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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