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Researchers develop new method to increase life span of donated brain tissue samples

Researchers at Lund University in Sweden have developed a method that enables them to use donated brain tissue from people with epilepsy for 48 hours. Previously, the researchers only had 12 hours to test new treatments before the structure of the cells started to break down. The research has now been published in the journal Scientific Reports.

9 Mar 2018

New study finds that thirdhand smoke increases lung cancer risk in mice

Researchers at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) identified thirdhand smoke, the toxic residues that linger on indoor surfaces and in dust long after a cigarette has been extinguished, as a health hazard nearly 10 years ago.

9 Mar 2018

Researchers show role for predictive biomarker in neonatal chronic lung disease pathogenesis

Extremely low birth-weight babies are at risk for a chronic lung disease called bronchopulmonary dysplasia, or BPD.

9 Mar 2018

Lower levels of protective molecules could increase heart attack risk in the morning

Cardiovascular disease patients have lower levels of an important family of protective molecules in their blood in the morning, which could be increasing their risk of blood clots and heart attacks at those times, according to early research led by Queen Mary University of London.

9 Mar 2018

Engineers develop optical tool that can read metabolism at subcellular resolution

Metabolic changes in cells can occur at the earliest stages of disease. In most cases, knowledge of those signals is limited, since we usually detect disease only after it has done significant damage. Now, a team led by engineers at Tufts University School of Engineering has opened a window into the cell by developing an optical tool that can read metabolism at subcellular resolution, without having to perturb cells with contrast agents, or destroy them to conduct assays.

9 Mar 2018

Impaired transport processes in neurons contribute to neurodegenerative disorders

Two partners have to find their way to each other in order to transport substances to the remote ends of special nerve fibers to maintain their function. If this partnering process is disturbed, the cells may die in the worst case, resulting in neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS) or spinal muscular atrophy.

9 Mar 2018

Novel screening tool aids search for curative kidney treatment

Researchers have developed a screening tool for identifying compounds that restore functionality of the protein that is dysfunctional in Alport syndrome.

9 Mar 2018

Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

Pancreatic cancer is one of the less common but deadliest cancers. Modified oncolytic adenoviruses represent an alternative to chemotherapy and targeted therapies, which have a high mortality rate.

9 Mar 2018

Cycling keeps the body young and healthy

Not surprisingly, a new study has shown that keeping active can keep the body young and healthy. The study comes from the researchers at the University of Birmingham and King's College London who were looking at the health of older adults who had been exercising most of their adult lives. The research has been reported in two papers published this week in the journal Aging Cell.

8 Mar 2018

Air pollution exposure during fetal life related to brain abnormalities, cognitive impairment in children

A new study performed in the Netherlands has linked exposure to residential air pollution during fetal life with brain abnormalities that may contribute to impaired cognitive function in school-age children. The study, published in Biological Psychiatry, reports that the air pollution levels related to brain alterations were below those considered to be safe.

8 Mar 2018

Study sheds light on earliest stages in evolution of male-female sexes

A new study published in the journal Communications Biology has shed light on the earliest stages in the evolution of male-female differentiation and sex chromosomes--and found the genetic origins of the two sexes to be unexpectedly modest.

8 Mar 2018

Researchers find link between increased proteostasis and immortality of stem cells

Stem cells are considered to be immortal in culture and, therefore, of great interest for aging research. This immortality is regulated by increased proteostasis, which controls the quality of proteins.

8 Mar 2018

Newly-discovered hereditary mutation leads to increased production of EPO in the blood

A newly-discovered hereditary mutation is responsible for an increased production of erythropoietin (EPO) in the blood.

8 Mar 2018

Study reveals key function of ALS-linked protein

The protein FUS, whose mutation or disruption causes many cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), works as a central component of one of the most important regulatory systems in cells, according to a new study in Molecular Cell from scientists at Johns Hopkins Bloomberg School of Public Health.

8 Mar 2018

New study examines origin of cryptococcosis within the central nervous system

A particular fungal infection is responsible for more than 220,000 cases of cryptococcosis worldwide each year in people with HIV and AIDS, with nearly 181,000 of those resulting in death.

8 Mar 2018

High-resolution fMRI provides clues about age-related memory differences

As we get older, it's not uncommon to experience "senior moments," in which we forget where we parked our car or call our children by the wrong names. And we may wonder: Are these memory lapses a normal part of aging, or do they signal the early stages of a severe disorder such as Alzheimer's disease? Currently, there's no good way to tell.

8 Mar 2018

Cell News and Research

Researchers develop new method to increase life span of donated brain tissue samples

New study finds that thirdhand smoke increases lung cancer risk in mice

Researchers show role for predictive biomarker in neonatal chronic lung disease pathogenesis

Lower levels of protective molecules could increase heart attack risk in the morning

Engineers develop optical tool that can read metabolism at subcellular resolution

Impaired transport processes in neurons contribute to neurodegenerative disorders

Novel screening tool aids search for curative kidney treatment

Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

Cycling keeps the body young and healthy

Air pollution exposure during fetal life related to brain abnormalities, cognitive impairment in children

Study sheds light on earliest stages in evolution of male-female sexes

Researchers find link between increased proteostasis and immortality of stem cells

Newly-discovered hereditary mutation leads to increased production of EPO in the blood

Study reveals key function of ALS-linked protein

New study examines origin of cryptococcosis within the central nervous system

High-resolution fMRI provides clues about age-related memory differences

Golgi stress signaling pathway found in cells with Huntington’s disease

Research reveals neuroprotective mechanisms of gene and cell medications for spinal cord injuries

Health care revamped at L.A. county jails

Researchers identify new mechanism to disrupt HIV latency

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