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Senate investigation culminates in report criticizing Medtronic

The Senate Finance Committee alleges that the medical technology company played a hidden role in drafting studies about one of its products.

29 Oct 2012

Triapine shows promise in treating breast cancer

Students at Tennessee Tech University are developing and testing a series of chemical compounds that show promise of stopping cancer in its tracks.

29 Oct 2012

Drug company to pay $95M to settle allegations of improper promotions for three drugs

Boehringer Ingelheim Pharmaceuticals Inc. will pay $95 million to settle allegations that the company promoted three drugs for uses that were not medically accepted, the government announced Thursday.

29 Oct 2012

New therapy to treat rare form of cystic fibrosis works in unconventional way, scientists say

Scientists at the Hospital for Sick Children in Toronto have established that a drug recently approved by the U.S. Food and Drug Administration to treat a rare form of cystic fibrosis works in an unconventional way.

29 Oct 2012

Routine ECG can help doctors identify patients at higher risk of adverse cardiovascular outcomes

Canadian scientists have determined that routine electrocardiogram results for patients with atrial fibrillation - the most common form of irregular heart beat - can help doctors identify those at higher risk of adverse cardiovascular outcomes, including death.

29 Oct 2012

Deutsche Welle examines emerging markets in developing countries for pharmaceutical industry

Deutsche Welle examines the widespread lack of access to medical supplies and drugs in developing countries and efforts by the pharmaceutical industry and others to bring new and lower-cost drugs into these emerging markets.

29 Oct 2012

HHS: Seniors saved $5B on prescription costs thanks to health law; Obama challenges Roberts on ACA ruling

In the meantime, President Obama splits with the Supreme Court on their reasoning behind upholding the health law.

29 Oct 2012

Scientists identify mechanism via Top2b enzyme that drives doxorubicin-induced heart damage

Doxorubicin, a 50-year-old chemotherapy drug still in widespread use against a variety of cancers, has long been known to destroy heart tissue, as well as tumors, in some patients.

29 Oct 2012

Resistin protein causes high levels of bad cholesterol

Canadian scientists have discovered that a protein called resistin, secreted by fat tissue, causes high levels of "bad" cholesterol (low-density lipoprotein or LDL), increasing the risk of heart disease.

29 Oct 2012

Research roundup: Patients' unrealistic expectations for chemo; Neighborhood may affect CPR rates; Rate hike reviews working

"To make informed decisions about whether to receive chemotherapy, patients with advanced lung or colorectal cancer need a realistic understanding of its likely benefits," the authors write. Researchers conducted comprehensive reviews of records.

29 Oct 2012

Pfizer receives FDA approval for Synribo to treat chronic myelogenous leukemia

The U.S. Food and Drug Administration today approved Synribo (omacetaxine mepesuccinate) to treat adults with chronic myelogenous leukemia (CML), a blood and bone marrow disease.

29 Oct 2012

New anti-thrombotic treatments in AF patients can reduce risk of stroke

Atrial fibrillation, whose prevalence continues to rise, was described last year as the "new epidemic" in cardiovascular disease, even though AF can be successfully controlled by the detection and management of risk factors, by rhythm control treatments, and by the use of antithrombotic therapies.

29 Oct 2012

Diabetes drug could treat illicit drug addiction

Researchers have found that a drug currently used to treat Type 2 diabetes could treat addiction to drugs such as cocaine.

26 Oct 2012

High worldwide drug-resistant TB figures are “worrying

The prevalence of resistance to second-line therapy among individuals with multi-drug resistant tuberculosis is high, show the results of a study conducted using data from eight countries worldwide.

26 Oct 2012

Cardiac arrhythmias: latest developments in diagnosis and treatment

A new Lancet Series explores the latest developments in the diagnosis, treatment and biology of cardiac arrhythmias, ahead of the American Heart Association’s annual meeting taking place this year on Nov 3–7 in Los Angeles, CA, USA.

26 Oct 2012

Researchers figure out 3D shape of promising TB drug target

Researchers at Johns Hopkins have figured out the three-dimensional shape of the protein responsible for creating unique bonds within the cell wall of the bacteria that cause tuberculosis. The bonds make the bacteria resistant to currently available drug therapies, contributing to the alarming rise of these super-bacteria throughout the world.

26 Oct 2012

Contaminated drug passed lab test

Products from the Massachusetts pharmacy linked to the deadly meningitis outbreak passed a lab test in May, reports The Wall Street Journal. In addition, the pharmacy dodged a reprimand by Massachusetts regulators in 2004 after protesting it would be "fatal to the business." The company's founders come under scrutiny by media outlets as more people file lawsuits.

26 Oct 2012

Journal of Pediatrics assesses issues surrounding lack of clinical drug trials for neonates

Clinical drug trials are a vital part of pharmaceutical manufacturers gaining approval for use by the U.S. Food and Drug Administration. A Commentary scheduled for publication in The Journal of Pediatrics assesses the issues surrounding the lack of clinical trials on medications used by children, most notably neonates, and how drug manufacturers and academic researchers could work together to create clinical trials that would benefit this underrepresented population.

26 Oct 2012

Malawi needs donor support to maintain HIV/AIDS treatment program

In the last of a series of posts on the U.K. Department for International Development's (DfID) blog examining the department's work in Malawi, Neil Squires, DfID head of profession for health, looks at the sustainability of the country's HIV/AIDS program.

26 Oct 2012

Associated Press examines access to antiretroviral treatment in Myanmar

The Associated Press examines access to antiretroviral treatment in Myanmar, which "ranks among the world's hardest places to get HIV care, and health experts warn it will take years to prop up a broken health system hobbled by decades of neglect."

26 Oct 2012

Drugs News and Research

Senate investigation culminates in report criticizing Medtronic

Triapine shows promise in treating breast cancer

Drug company to pay $95M to settle allegations of improper promotions for three drugs

New therapy to treat rare form of cystic fibrosis works in unconventional way, scientists say

Routine ECG can help doctors identify patients at higher risk of adverse cardiovascular outcomes

Deutsche Welle examines emerging markets in developing countries for pharmaceutical industry

HHS: Seniors saved $5B on prescription costs thanks to health law; Obama challenges Roberts on ACA ruling

Scientists identify mechanism via Top2b enzyme that drives doxorubicin-induced heart damage

Resistin protein causes high levels of bad cholesterol

Research roundup: Patients' unrealistic expectations for chemo; Neighborhood may affect CPR rates; Rate hike reviews working

Pfizer receives FDA approval for Synribo to treat chronic myelogenous leukemia

New anti-thrombotic treatments in AF patients can reduce risk of stroke

Diabetes drug could treat illicit drug addiction

High worldwide drug-resistant TB figures are “worrying

Cardiac arrhythmias: latest developments in diagnosis and treatment

Researchers figure out 3D shape of promising TB drug target

Contaminated drug passed lab test

Journal of Pediatrics assesses issues surrounding lack of clinical drug trials for neonates

Malawi needs donor support to maintain HIV/AIDS treatment program

Associated Press examines access to antiretroviral treatment in Myanmar

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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