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Illumina announces first named family DNA sequence

Illumina, Inc. today announced that it has sequenced the DNA of John, Judy, Anne and Paul West, the first publicly named family to have their DNA sequenced to full coverage by the company.

From Illumina, Inc. 17 Apr 2010

Genomic portrait may predict liver cancer recurrence: Study

Results of an international clinical study conducted in Europe and the US presented today at the International Liver CongressTM 2010, the Annual Meeting of the European Association for the Study of Liver in Vienna, Austria, have identified a genomic portrait able to predict recurrence in hepatocellular carcinoma (HCC), the fifth most common cancer in men.

17 Apr 2010

Marker found in iPS cells correlates with levels of pluripotency: Researchers

Researchers in China are reporting that they have found a way to determine which somatic cells -- or differentiated body cells -- that have been reprogrammed into a primordial, embryonic-like state are the most viable for therapeutic applications.

17 Apr 2010

ADHD behaviors in children associated with serotonin activity and self-blame

ADHD may be caused by alterations in the serotonin neurotransmission system combined with a tendency to experience psychosocial distress. Researchers writing in BioMed Central's open access journal Behavioral and Brain Functions found that ADHD behaviors in children and adolescents were associated with interactions between low and high serotonin activity and self-blame in relation to inter-parental conflict.

17 Apr 2010

Researchers receive honorary Doctor of Medicine degrees

Two genetics researchers from the Johns Hopkins University School of Medicine have been awarded prestigious honorary Doctor of Medicine degrees by European scientific institutions.

17 Apr 2010

Calorie restriction may help people to lead longer and healthier lives

Organisms from yeast to rodents to humans all benefit from cutting calories. In less complex organisms, restricting calories can double or even triple lifespan. It's not yet clear just how much longer calorie restriction might help humans live, but those who practice the strict diet hope to survive past 100 years old.

16 Apr 2010

DNA modification can define early onset glioblastoma

A class of brain tumor that tends to emerge in younger patients but is less aggressive than others can be identified by examining DNA methylation of a specific set of genes, scientists at The University of Texas M. D. Anderson Cancer Center and colleagues with The Cancer Genome Atlas report today online at Cancer Cell.

16 Apr 2010

RUCDR is poised to become a world leader in human disease and genome studies

Despite the continuing, crippling effects of a nationwide recession, a genetics research laboratory on Rutgers' Busch Campus is experiencing an economic boom.

16 Apr 2010

Researchers say exclusive licensing on genes could hurt patients

The Wall Street Journal reports that Duke University researchers have found in a study published Wednesday that granting "exclusive licenses on individual genes" could hurt patients' chances of pinpointing their risks to develop disease.

16 Apr 2010

Embryos with two mums to remove the risk of hereditary diseases: new research

New research published in the journal Nature, could pave the way to world’s first genetically modified human baby. The research involves making embryos with genes from one man and two women. There are hundreds or families around the world who are left childless or have serious ill babies because they carry genes for hereditary illnesses. This research may bring hope to such couples. According to scientists on the team, within the next three years these women will be able to avail such techniques. There has been skepticism regarding ethical issues attached to making of “designer babies”.

16 Apr 2010

Nottingham and Japanese scientists to study genetic variation of E. coli bacteria

University of Nottingham scientists will join forces with Japan in the fight against a common bacterium - thanks to an international research award.

16 Apr 2010

Certain genetic variations linked to tooth decay, periodontitis

Certain genetic variations may be linked to higher rates of tooth decay and aggressive periodontitis, according to two recently published papers by researchers at the University of Pittsburgh School of Dental Medicine and their collaborators.

16 Apr 2010

Regulus Therapeutics' metabolic disease program data presented at Diabetes Keystone Symposium

Regulus Therapeutics Inc. today announced that new data from its metabolic disease program were presented at the "Diabetes" Keystone Symposium held April 12-17 in Whistler, British Columbia. The new pre-clinical research findings showed that therapeutic oligonucleotides targeting microRNA are able to improve insulin resistance and normalize plasma glucose in mouse models of diabetes while having no significant effect on glucose or insulin levels in normal mice.

16 Apr 2010

Study on primary cilia formation may lead to new therapies for ciliopathies

A team of scientists at the University of California, San Diego School of Medicine have identified a network of genes that initiate and manage cilia formation. Although scientists have known about cilia for decades, only recently have they discovered their role in disease. This new discovery, which may lead to new therapies for ciliopathies, will appear in the April 15 edition of Nature.

16 Apr 2010

Consortium studies gene-drug relationship to determine optimal warfarin doses

If Julie Johnson had her way, doctors would check a patient's genes before writing a prescription. Everyone responds differently to medicines—one that works for you might not work for me, or it could even be harmful. These individual responses depend to an extent on our genetic make-up.

16 Apr 2010

Obesity prejudice in medical community

Prejudice towards obese people is rife among trainee health professionals, but can be modified, new research has found.

16 Apr 2010

Albert Einstein College of Medicine of Yeshiva University receives funds to expand stem cell research capabilities

Albert Einstein College of Medicine of Yeshiva University has been awarded $10 million from the National Institutes of Health to expand its stem cell research capabilities. The funds will be used to create new laboratories in order to increase its already substantial base of stem cell investigators.

16 Apr 2010

Research may provide better clinical outcomes for patients with aggressive type of brain cancer

A study conducted by a collaborative team led by researchers from the University of Southern California (USC) may lead to better insight into the clinical outcome for some patients with a particularly aggressive type of brain cancer. The research may also provide a framework for development of targeted drug treatments.

16 Apr 2010

Exclusive licensing practices slows innovation in gene testing market

Exclusive licenses to gene patents, most of which are held by academic institutions and based on taxpayer-funded research, do more to block competition in the gene testing market than to spur the development of new technologies for gauging disease risk, say researchers at the Duke Institute for Genome Sciences & Policy (IGSP).

15 Apr 2010

Foundation Medicine completes $25M Series A financing led by Third Rock Ventures

Foundation Medicine, a personalized cancer medicine company that aims to bring comprehensive cancer genome analysis into routine clinical care, today announced it has completed a $25 million Series A financing led by Third Rock Ventures.

15 Apr 2010