Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Variations in the neutralization of SARS-CoV-2 variants in vaccinated mice and primates

In a new study, researchers demonstrated the variations in the neutralizing antibody responses induced by SARS-CoV-2 vaccines in humans, non-human primates, and mice against the SARS-CoV-2 variants of concern.

14 Feb 2022

Study describes a β-CoV spike protein target for protective antibodies that may facilitate pan-β-CoV vaccine development

In a recent study published in Science Translational Medicine, researchers characterized a human antibody targeting betacoronaviruses (β-CoVs).

14 Feb 2022

Study demonstrates associations between COVID-19 symptom presentation and antibody assay reactivity

Researchers tested convalescent sera from individuals who had recovered from SARS-CoV-2 infection to demonstrate an association between antibody response and reported COVID-19 symptoms.

14 Feb 2022

An alternative strategy targeting furin disrupts SARS-CoV-2 infection cycle

A new study was based on the hypothesis that competitively inhibiting cellular furin and selectively targeting SARS-CoV-2 in the infected viral-producing cells is critical for therapeutic specificity.

14 Feb 2022

Study shows expression of viral proteases may be used to quantitate SARS-CoV-2 infected cells

A new study describes a new method to quantify SARS-CoV-2 infection, which is much simpler and faster compared to existing methods.

14 Feb 2022

Researchers identify autoantibody targets in COVID-19 patients

In a new study, researchers have been investigating auto-immune responses to natural human antigens in COVID-19 patients.

14 Feb 2022

Study finds mRNA vaccines induce poor neutralizing antibody response against SARS-CoV-2 variants in dialysis patients

Scientists studied plasma samples from 130 hemodialysis (HD) and 13 peritoneal dialysis patients and showed a poor neutralizing and rapidly decaying antibody response to mRNA vaccines in such individuals.

14 Feb 2022

How a third booster BNT162b2 dose impacts anti-spike antibody levels

A new study aimed to investigate the mechanism by which the third booster BNT162b2 dose impacts anti-S levels.

14 Feb 2022

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

In a study posted to the bioRxiv* preprint server, a team of researchers from the United States evaluated the protective effect of the preclinical version of the current Moderna Omicron-targeted mRNA-1273.529 vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 Omicron infection in mice.

14 Feb 2022

Study looks at potential impact of BBIBPCorV and CoronaVac SARS-CoV-2 vaccines on thyroid

In a recent study posted to Preprints with The Lancet* server, a team of researchers from China performed a serology study of thyroid function and antithyroid antibody levels in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-vaccinated recipients and further evaluated their correlation with SARS-CoV-2 neutralizing antibodies (NAbs) levels.

14 Feb 2022

Study shows IgA antibodies play a significant role in neutralizing SARS-CoV-2

A recent paper by researchers from Australia, currently available on the medRxiv* preprint server, shows how Immunoglobulin A (IgA) antibodies in individuals who were infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contribute to the neutralization of the virus and its variants, even though this response is heterogeneous and less potent when compared to IgG antibodies.

13 Feb 2022

90 minutes of exercise after vaccination may provide an extra immune boost

Researchers at Iowa State University found 90 minutes of mild- to moderate-intensity exercise directly after a flu or COVID-19 vaccine may provide an extra immune boost.

12 Feb 2022

Performance of SARS-CoV-2 antibodies improves only after previous infection, not vaccination

New research to be presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2022, Lisbon, 23-26 April) shows that, although over time the number of SARS-CoV-2 antibodies falls in both previously infected and vaccinated patients, the performance of antibodies improves only after previous infection (and not vaccination).

11 Feb 2022

New insights into the effects of COVID-19 vaccination on dialysis patients

Two studies in CJASN offer a better understanding of the effects of COVID-19 vaccination on individuals with kidney failure who are undergoing long-term dialysis.

11 Feb 2022

Scientists decipher molecular cause of cerebral venous thrombosis

Cerebral venous thrombosis is a rare, often severe disease that has been brought to public attention by the Covid 19 pandemic. A research group from Würzburg has now succeeded for the first time in deciphering a molecular cause of this disease.

11 Feb 2022

Model shows booster doses and antiviral pills may enable relaxation of SARS-CoV-2 social distancing

Researchers suggest that social distancing could be relaxed in order to reduce the number of severe cases of COVID-19, rather than stop the transmission of the SARS-CoV-2.

11 Feb 2022

Study investigates population immunity to SARS-CoV-2 through heterogenous pathways

A new study demonstrates COVID-19 vaccine-specific differences in the antibody responses and memory B-cell immunity in a sample population comprising of 197 vaccinated individuals in Mexico.

11 Feb 2022

Direct oral anti-coagulants less likely to result in major bleeding after rare, fatal stroke

Direct oral anti-coagulant (anti-clotting) (DOAC) medications that target a single clotting factor work just as well to prevent future clots as the older, less-specific medication warfarin.

11 Feb 2022

New analysis highlights growing trends in combination cancer therapy clinical trials

The Cancer Research Institute, a nonprofit organization dedicated to the discovery and development of powerful immunotherapies for all types of cancer, announced today the publication of its newest analysis of the global landscape of clinical development of drugs that target the PD1/PDL1 immune checkpoint pathway.

10 Feb 2022

Spillover of SARS-CoV-2 Omicron variant infection in white-tailed deer in New York

Researchers detected evidence for SARS-CoV-2 Omicron variant exposure in the white-tailed deer population inhabiting Staten Island in New York.

10 Feb 2022

Antibody News and Research

Further Reading

Variations in the neutralization of SARS-CoV-2 variants in vaccinated mice and primates

Study describes a β-CoV spike protein target for protective antibodies that may facilitate pan-β-CoV vaccine development

Study demonstrates associations between COVID-19 symptom presentation and antibody assay reactivity

An alternative strategy targeting furin disrupts SARS-CoV-2 infection cycle

Study shows expression of viral proteases may be used to quantitate SARS-CoV-2 infected cells

Researchers identify autoantibody targets in COVID-19 patients

Study finds mRNA vaccines induce poor neutralizing antibody response against SARS-CoV-2 variants in dialysis patients

How a third booster BNT162b2 dose impacts anti-spike antibody levels

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

Study looks at potential impact of BBIBPCorV and CoronaVac SARS-CoV-2 vaccines on thyroid

Study shows IgA antibodies play a significant role in neutralizing SARS-CoV-2

90 minutes of exercise after vaccination may provide an extra immune boost

Performance of SARS-CoV-2 antibodies improves only after previous infection, not vaccination

New insights into the effects of COVID-19 vaccination on dialysis patients

Scientists decipher molecular cause of cerebral venous thrombosis

Model shows booster doses and antiviral pills may enable relaxation of SARS-CoV-2 social distancing

Study investigates population immunity to SARS-CoV-2 through heterogenous pathways

Direct oral anti-coagulants less likely to result in major bleeding after rare, fatal stroke

New analysis highlights growing trends in combination cancer therapy clinical trials

Spillover of SARS-CoV-2 Omicron variant infection in white-tailed deer in New York

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