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SMOC1 gene plays a surprising role in the development of type 2 diabetes

Scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S., and a leading research center for diabetes and other life-threatening illnesses, have uncovered a gene called SMOC1 that plays a surprising role in the development of type 2 diabetes (T2D) by converting pancreatic cells that normally produce insulin into those that increase blood sugar.

7 Oct 2025

Deregulated miR-145 and miR-27b impact adipogenesis in Hutchinson-Gilford progeria syndrome

A new research paper was published in Volume 17, Issue 9 of Aging-US on August 27, 2025, titled, "Deregulated miR-145 and miR-27b in Hutchinson-Gilford progeria syndrome: implications for adipogenesis."

7 Oct 2025

NCCN enhances widely used breast cancer guidelines with advanced digital features

Today, the National Comprehensive Cancer Network® (NCCN®)-a nonprofit responsible for globally utilized guidelines for cancer care-is sharing new NCCN Guidelines Navigator™ resources for breast cancer treatment as well as genetic/familial high-risk assessment, during Breast Cancer Awareness Month.

7 Oct 2025

IASLC proposes new tumor budding-based grading system for lung squamous cell carcinoma

Invasive lung squamous cell carcinoma (LUSC) accounts for approximately one-quarter of all lung cancers, but therapeutic options for LUSC remain limited, primarily due to the absence of well-defined, targetable molecular alterations.

6 Oct 2025

PAHO and ORAS-CONHU renew cooperation agreement to strengthen Andean health systems

Today the Pan American Health Organization (PAHO) and the Andean Health Organization - Hipólito Unanue Agreement (ORAS-CONHU) extended the Memorandum of Understanding that consolidates their cooperation framework through 2029.

6 Oct 2025

Nanotechnology breakthrough reverses Alzheimer’s disease in mice

A research team co-led by the Institute for Bioengineering of Catalonia (IBEC) and West China Hospital Sichuan University (WCHSU), working with partners in the UK, has demonstrated a nanotechnology strategy that reverses Alzheimer's disease in mice.

6 Oct 2025

Microplastics can alter the human gut microbiome, research shows

New research presented today at UEG Week 2025 shows that microplastics – plastic particles smaller than 5mm commonly found in the environment – can alter the human gut microbiome, with some changes resembling patterns linked to depression and colorectal cancer.

6 Oct 2025

Breakthrough in RNA-targeted drug discovery offers hope against viral diseases

In a quest to develop new antiviral drugs for COVID-19 and other diseases, a collaboration led by scientists at The Wertheim UF Scripps Institute has identified a potential new drug against the virus that causes COVID-19.

6 Oct 2025

DKMS advances blood cancer research with groundbreaking ASAP study

The selection of patients for allo-HSCT and the best approach to bridging patients to transplantation is continuously discussed by experts.

6 Oct 2025

Paternal exercise enhances offspring endurance through sperm microRNAs

In a recent study published in Cell Metabolism, a collaborative research team led by Chen-Yu Zhang, Xi Chen, and Di-Jun Chen from Nanjing University, together with Tao Zhang from Nanjing Medical University, reported groundbreaking findings in their paper entitled "Paternal exercise confers endurance capacity to offspring through sperm microRNAs."

6 Oct 2025

Milken Institute and Ann Theodore Foundation award over $2.5 million for sarcoidosis research

The Milken Institute Science Philanthropy Accelerator for Research and Collaboration (SPARC), in partnership with the Ann Theodore Foundation (ATF), today announced that the Ann Theodore Foundation Breakthrough Sarcoidosis Initiative (ATF-BSI) has awarded five grants totaling more than $2.5 million to interdisciplinary research teams.

6 Oct 2025

FDA grants approval to begin Phase I clinical trials of heart tissue regeneration drug AD-NP1

The body's tissues can get injured in many ways, but while some injuries heal perfectly, others don't heal at all. A cut in the skin, for example, usually heals all on its own, while internal organs, such as the heart after a heart attack or the kidney after an acute injury, remain damaged, leading to diminished function.

6 Oct 2025

Moffitt awarded $22.4 million grant to lead novel studies and clinical trials for leptomeningeal disease

Researchers at Moffitt Cancer Center have been awarded a $22.4 million grant from the U.S. Department of War to lead groundbreaking studies and clinical trials for leptomeningeal disease, a devastating complication of breast and other cancers that spreads to the coverings of the brain and spinal cord.

6 Oct 2025

Study shows c-Kit–expressing sweet cells are central to taste bud regeneration after nerve injury

Taste is one of our most vital senses, shaping appetite, nutrition, and quality of life. Yet taste buds are fragile, relying heavily on the nerves that connect them to the brain.

6 Oct 2025

Common food additives may trigger childhood asthma

Researchers utilize metabolomics to investigate the mechanisms underlying the association between food additives and childhood asthma.

6 Oct 2025

Azelastine nasal spray prevents COVID-19 and rhinovirus infections

Researchers discuss the effects of azelastine nasal spray on the rate of SARS-CoV-2 infection as compared to placebo.

6 Oct 2025

Researchers identify a central controller of mitochondrial dynamics in disease

A key switch for cellular energy balance has been discovered in cells: it could potentially become the target of new therapies for diseases ranging from Parkinson's to rare disorders caused by defects in the cell's powerhouses, the mitochondria.

6 Oct 2025

AI-designed proteins revolutionize gene editing precision and safety

Researchers at Integra Therapeutics, in collaboration with the Pompeu Fabra University (UPF) Department of Medicine and Life Sciences (MELIS) and the Center for Genomic Regulation (CRG), have designed and experimentally validated new synthetic proteins that can edit the human genome more efficiently than proteins provided by nature.

6 Oct 2025

New research reveals the cervix as a truly immunocompetent tissue

Cervical epithelial cells are far from passive bystanders in the body's immune system. New research shows they actually play an active and highly coordinated role in detecting and fighting infections. That's the conclusion of an international research team led by Associate Professor Cindrilla Chumduri from Aarhus University, and now published in the journal Science Advances.

6 Oct 2025

Study reveals new strategy to block TNBC metastasis and restore chromosomal stability

Triple negative breast cancer (TNBC) is one of the most aggressive and hardest forms of breast cancer to treat, but a new study led by Weill Cornell Medicine suggests a surprising way to stop it from spreading. Researchers have discovered that an enzyme called EZH2 drives TNBC cells to divide abnormally, which enables them to relocate to distant organs.

6 Oct 2025

Cell News and Research

SMOC1 gene plays a surprising role in the development of type 2 diabetes

Deregulated miR-145 and miR-27b impact adipogenesis in Hutchinson-Gilford progeria syndrome

NCCN enhances widely used breast cancer guidelines with advanced digital features

IASLC proposes new tumor budding-based grading system for lung squamous cell carcinoma

PAHO and ORAS-CONHU renew cooperation agreement to strengthen Andean health systems

Nanotechnology breakthrough reverses Alzheimer’s disease in mice

Microplastics can alter the human gut microbiome, research shows

Breakthrough in RNA-targeted drug discovery offers hope against viral diseases

DKMS advances blood cancer research with groundbreaking ASAP study

Paternal exercise enhances offspring endurance through sperm microRNAs

Milken Institute and Ann Theodore Foundation award over $2.5 million for sarcoidosis research

FDA grants approval to begin Phase I clinical trials of heart tissue regeneration drug AD-NP1

Moffitt awarded $22.4 million grant to lead novel studies and clinical trials for leptomeningeal disease

Study shows c-Kit–expressing sweet cells are central to taste bud regeneration after nerve injury

Common food additives may trigger childhood asthma

Azelastine nasal spray prevents COVID-19 and rhinovirus infections

Researchers identify a central controller of mitochondrial dynamics in disease

AI-designed proteins revolutionize gene editing precision and safety

New research reveals the cervix as a truly immunocompetent tissue

Study reveals new strategy to block TNBC metastasis and restore chromosomal stability

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