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Researchers devise new approach to improve current T-cell therapy methods

T-cell therapy, a form of immunotherapy that uses a patient's own immune cells to attack their cancer, has been making waves recently. The "living" therapy involves engineering the patient's T cells in the laboratory to carry new proteins that guide the immune cells directly to tumor cells, allowing the engineered T cells to attack and kill the cancer.

23 Feb 2016

Cardiac clot-busting drug decreases mortality in hemorrhagic stroke patients

Reporting on the results of a phase III international clinical trial, Johns Hopkins Medicine physicians say use of a cardiac clot-busting drug to treat strokes that cause brain bleeding safely decreased the death rate in patients by 10 percent, compared to a control group receiving saline.

23 Feb 2016

New clinical trial focuses on respiratory drug ambroxol for treatment of Parkinson's disease

A medication approved to treat various respiratory diseases and that has demonstrated neuroprotective effects in preclinical studies is the focus of a new clinical trial for Parkinson's disease.

23 Feb 2016

UCSF study finds specific molecular-genetic mechanism that links sleep and seasonal depression

A newly discovered human gene mutation appears to contribute both to unusual sleep patterns and to heightened rates of seasonal depression, according to new research from UC San Francisco.

23 Feb 2016

SIFT 4G software can lead to faster genome analysis

An international team of scientists, led by researchers from A*STAR's Genome Institute of Singapore (GIS) and the Bioinformatics Institute (BII), have developed SIFT 4G (SIFT for Genomes) - a software that can lead to faster genome analysis.

23 Feb 2016

Study identifies new mechanism for controlling HIV replication

Researchers at University of California, San Diego School of Medicine have discovered that HIV infection of human immune cells triggers a massive increase in methylation, a chemical modification, to both human and viral RNA, aiding replication of the virus.

23 Feb 2016

FDA-approved VENTANA anti-ALK CDx more accurate than commonly used IHC assay for patient selection

The U.S. Food and Drug Administration approved VENTANA anti-ALK(D5F3)CDx performed more accurately than another commonly used immunohistochemistry (IHC) assay, based on the use of the 5A4 clone, for the selection of patients eligible to receive ALK tyrosine kinase inhibitor (TKI) treatment.

23 Feb 2016

Maternal supplementation with docosahexaenoic acid improves fetal iron metabolism

A research has proven, for the first time, that maternal supplementation with docosahexaenoic acid (DHA), an omega-3 essential polyunsaturated fatty acid, enhances fetal iron metabolism thanks to a greater expression of key genes regulating its transfer through the placenta.

23 Feb 2016

Understanding risk factors that contribute to childhood obesity

As the rate of obesity in the U.S. population has risen dramatically, more and more children are becoming overweight at younger and younger ages. Understanding the factors that contribute to childhood obesity and identifying ways to prevent its development are critical to stemming the historically high prevalence of childhood obesity and of associated health problems like type 2 diabetes.

22 Feb 2016

EPFL researchers develop portable microfluidic diagnostic device to detect different diseases

When remote regions with limited health facilities experience an epidemic, they need portable diagnostic equipment that functions outside the hospital. As demand for such equipment grows, EPFL researchers have developed a low-cost and portable microfluidic diagnostic device. It has been tested on Ebola and can be used to detect many other diseases.

22 Feb 2016

Fight cravings and maintain a healthy weight

Many of us think that we are taking the right steps in being healthy, which means it can be frustrating when we are not feeling as energetic and happy as we would like. There are many factors that you may not even think about, such as stress, which can lead our bodies to release glucose to the blood stream quickly, which usually gets converted into energy and with many of us living inactive lifestyles the glucose turns to fat.

22 Feb 2016

FSU researchers explore new method to decipher genetic data for new prostate cancer treatments

Florida State University researchers are working on new approaches to deciphering genetic data that may lead to new, more targeted prostate cancer treatments.

22 Feb 2016

Researchers analyze how Topo II enzyme may affect stability of genomes

While researchers are now familiar with how cancer begins—cells mutate and then multiply wildly out of control—it is still uncertain exactly how that mutation starts in the molecules of the cells.

22 Feb 2016

Berlin researchers use T cells to target mutations in cancer cells

The efficacy of the immune system to combat disease makes the body's own healing powers a promising approach in the fight against cancer. A Berlin research group led by Wolfgang Uckert, Thomas Blankenstein and Matthias Leisegang has been collaborating with U.S. researcher Hans Schreiber in a project to use immune components called T cells to target mutant proteins produced by cancer cells.

22 Feb 2016

UCLA-led researchers identify specific gene network that promotes repair in peripheral nervous system

Whether or not nerve cells are able to regrow after injury depends on their location in the body. Injured nerve cells in the peripheral nervous system, such as those in the arms and legs, can recover and regrow, at least to some extent. But nerve cells in the central nervous system -- the brain and spinal cord -- can't recover at all.

22 Feb 2016

Calgary researchers develop new class of nanomedicines to treat autoimmune diseases

A new study from the University of Calgary could change the way researchers understand and treat autoimmune diseases such as type 1 diabetes, multiple sclerosis and rheumatoid arthritis.

22 Feb 2016

Dr. Elliot J. Androphy receives IGNITE grant to develop drug candidate for spinal muscular atrophy

Dr. Elliot J. Androphy, the Kampen-Norins Professor and chair of the Department of Dermatology at the Indiana University School of Medicine, has been awarded an IGNITE, or Innovation Grants to Nurture Initial Translational Efforts, grant by the National Institutes of Health.

22 Feb 2016

New molecular delivery system could help ensure delivery of chemotherapy drugs into tumours

Chemotherapy isn't supposed to make your hair fall out -- it's supposed to kill cancer cells. A new molecular delivery system created at U of T Engineering could help ensure that chemotherapy drugs get to their target while minimizing collateral damage.

22 Feb 2016

Australian researchers reveal how nutlins pave way for improving future of cancer treatment

Australian researchers have resolved a mystery about how a promising new class of anti-cancer drugs, called nutlins, work - paving the way for improving the future of cancer treatment.

22 Feb 2016

3-D map of critical protein could lead to new malaria vaccine

A three-dimensional 'map' of a critical protein that malaria parasites use to invade human red blood cells could lead to a vaccine countering the most widespread species of the parasite.

22 Feb 2016

G Protein News and Research

Researchers devise new approach to improve current T-cell therapy methods

Cardiac clot-busting drug decreases mortality in hemorrhagic stroke patients

New clinical trial focuses on respiratory drug ambroxol for treatment of Parkinson's disease

UCSF study finds specific molecular-genetic mechanism that links sleep and seasonal depression

SIFT 4G software can lead to faster genome analysis

Study identifies new mechanism for controlling HIV replication

FDA-approved VENTANA anti-ALK CDx more accurate than commonly used IHC assay for patient selection

Maternal supplementation with docosahexaenoic acid improves fetal iron metabolism

Understanding risk factors that contribute to childhood obesity

EPFL researchers develop portable microfluidic diagnostic device to detect different diseases

Fight cravings and maintain a healthy weight

FSU researchers explore new method to decipher genetic data for new prostate cancer treatments

Researchers analyze how Topo II enzyme may affect stability of genomes

Berlin researchers use T cells to target mutations in cancer cells

UCLA-led researchers identify specific gene network that promotes repair in peripheral nervous system

Calgary researchers develop new class of nanomedicines to treat autoimmune diseases

Dr. Elliot J. Androphy receives IGNITE grant to develop drug candidate for spinal muscular atrophy

New molecular delivery system could help ensure delivery of chemotherapy drugs into tumours

Australian researchers reveal how nutlins pave way for improving future of cancer treatment

3-D map of critical protein could lead to new malaria vaccine

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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