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Frequent zoonotic spillover of diverse sarbecoviruses in communities interacting with wildlife

A new study published in the International Journal of Infectious Diseases surveyed communities in rural Myanmar to study their exposure to sarbecoviruses and interaction with wildlife.

6 Mar 2023

Study identifies genetic variants influencing human fertility

Fertility is influenced by mechanisms that influence both reproductive biology and human behavior, according to the largest study to date identifying genetic determinants of the number of children an individual may have.

6 Mar 2023

How does chronic HBV infection affect flu and COVID-19 vaccine responses?

The influenza season marks the beginning of a time of illness, sometimes serious or even fatal, in much of the world. For this reason, flu shots are recommended, especially for individuals with underlying diseases such as chronic hepatitis B (CHB) infection, since they are at higher risk for adverse outcomes.

6 Mar 2023

Fighting pancreatic cancer with gene and cell biotherapies

Pancreatic cancer is an incurable form of cancer, and gene therapies are currently in clinical testing to treat this deadly disease. A comprehensive review of the gene and cell biotherapies in development to combat pancreatic cancer is published in the peer-reviewed journal Human Gene Therapy.

6 Mar 2023

Coordinated, multifaceted intervention can improve preventive care for diabetes, heart disease

A multifaceted intervention to improve prescribing practices increased the likelihood that patients with Type 2 diabetes and heart disease would be prescribed three classes of guideline-recommended medications by more than fourfold, according to research being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Meta-analysis on COVID-19 vaccine effectiveness in association with antibody titers

Researchers performed a meta-analysis analyzing randomized controlled trials (RCTs) that evaluated the effectiveness of coronavirus disease 2019 (COVID-19) vaccines, and the dose-response association of humoral responses with vaccine effectiveness.

6 Mar 2023

Electronic notifications boost the prescription of life-saving cardiology drug

An automated system that flags which patients could most benefit from an underused yet life-saving cardiology drug more than doubled new prescriptions, according to a pilot program test by researchers at NYU Grossman School of Medicine.

5 Mar 2023

Association between cardiovascular disease and transportation noise revealed in new research

Researchers assessed the association between cardiovascular disease and transportation noise.

3 Mar 2023

Gene mutation capable of regulating pain discovered

Pain afflicts at least 1.5 billion people worldwide, and despite the availability of various painkilling drugs, not all forms of pain are treatable.

3 Mar 2023

Researchers develop a potential treatment for autoimmune encephalitis

In autoimmune encephalitis, a rare but serious and sometimes life-threatening inflammation of the central nervous system, the body's own defenses are directed against the central nervous system.

3 Mar 2023

Engineering epitope scaffolds of conserved regions of SARS-CoV-2 spike

In a recent study posted to the bioRxiv* preprint server, researchers engineered epitope scaffolds (ESs) of conserved regions of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

3 Mar 2023

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Researchers performed multi-organ single-cell RNA sequencing of collagen-induced arthritis murine model to evaluate immune-mediated inflammatory disease alterations by characterizing the genome, organizing the organome, and prioritizing pathways in the multi-organ data.

3 Mar 2023

Neutral or awkward behavior of mothers with infants linked to an epigenetic change in children

Adding evidence to the importance of early development, a new study links neutral maternal behavior toward infants with an epigenetic change in children related to stress response.

2 Mar 2023

Starting immunotherapy before surgery improves the outlook for patients with stage III-IV melanoma

Patients with high-risk melanoma who received the immunotherapy drug pembrolizumab both before and after surgery to remove cancerous tissue had a significantly lower risk of their cancer recurring than similar patients who received the drug only after surgery.

1 Mar 2023

Researchers use spatial single-cell transcriptome technique to examine immune signatures of SARS-CoV-2-infected lungs

The study findings demonstrate the power of spatial single-cell transcriptomics in studying COVID-19 lung pathology and other health and disease conditions.

1 Mar 2023

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

In a recent study published in Cells, researchers evaluated idiopathic pulmonary fibrosis (IPF) pathophysiological differences by sex and intestinal microbiome.

1 Mar 2023

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

In a recent review published in Biomedicines, researchers explored extracellular vesicles (EVs), cell-penetrating peptides (CPPs), and micro ribonucleic acids (miRNAs) as therapies for neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD).

1 Mar 2023

What is the role of B cells in breast cancer pathology?

In a recent study published in Cancers, researchers comprehensively summarized all available information about B cells in the context of breast cancer.

1 Mar 2023

Bacteria exploit nerve cells in the meninges to facilitate brain invasion

A new study led by researchers at Harvard Medical School details the step-by-step cascade that allows bacteria to break through the brain's protective layers - the meninges - and cause brain infection, or meningitis, a highly fatal disease.

1 Mar 2023

Evidence that cross-reactive immunity from common human coronaviruses can influence response to SARS-CoV-2

In a recent study published in the journal Vaccines, researchers in Saudi Arabia and the United States examined immune responses and immunoglobulin G (IgG) cross-reactivity in individuals infected with Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

28 Feb 2023

Receptor News and Research

Frequent zoonotic spillover of diverse sarbecoviruses in communities interacting with wildlife

Study identifies genetic variants influencing human fertility

How does chronic HBV infection affect flu and COVID-19 vaccine responses?

Fighting pancreatic cancer with gene and cell biotherapies

Coordinated, multifaceted intervention can improve preventive care for diabetes, heart disease

Meta-analysis on COVID-19 vaccine effectiveness in association with antibody titers

Electronic notifications boost the prescription of life-saving cardiology drug

Association between cardiovascular disease and transportation noise revealed in new research

Gene mutation capable of regulating pain discovered

Researchers develop a potential treatment for autoimmune encephalitis

Engineering epitope scaffolds of conserved regions of SARS-CoV-2 spike

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Neutral or awkward behavior of mothers with infants linked to an epigenetic change in children

Starting immunotherapy before surgery improves the outlook for patients with stage III-IV melanoma

Researchers use spatial single-cell transcriptome technique to examine immune signatures of SARS-CoV-2-infected lungs

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

What is the role of B cells in breast cancer pathology?

Bacteria exploit nerve cells in the meninges to facilitate brain invasion

Evidence that cross-reactive immunity from common human coronaviruses can influence response to SARS-CoV-2

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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