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Reduced conflict-related brain activity linked to higher risk for psychosis

Researchers led by Bradley S. Peterson, MD, director of the Institute for the Developing Mind at Children's Hospital Los Angeles, have shown that lower levels of conflict-related brain activity are associated with a higher risk for later psychosis.

23 Sep 2015

Subtle differences in brain function make women react differently to negative emotions, shows research

Women react differently to negative images compared to men, which may be explained by subtle differences in brain function.

23 Sep 2015

Gene study reveals how a strain of E. coli evolved to become potentially fatal infection

A strain of E. coli became a potentially fatal infection in the UK around 30 years ago, when it acquired a powerful toxin, a gene study has revealed.

22 Sep 2015

UCI scientists find potential biomarker for diagnosing certain forms of autism

By identifying a key signaling defect within a specific membrane structure in all cells, University of California, Irvine researchers believe, they have found both a possible reliable biomarker for diagnosing certain forms of autism and a potential therapeutic target.

22 Sep 2015

$Bisphosphonate drugs linked to greater risk of atypical hip fractures$

Bisphosphonate drugs linked to greater risk of atypical hip fractures

The use of bisphosphonates, a group of drugs used to prevent hip breakages in women with osteoporosis, is associated with an increased risk of atypical fractures in this joint, understood as those that occur in less frequent locations.

22 Sep 2015

Type 2 diabetes risk grows with active and passive smoking

A meta-analysis of 88 studies covering nearly 6 million people published in The Lancet Diabetes & Endocrinology shows that both active and passive smoking are linked to increased risk of type 2 diabetes, while the risk in those who quit smoking decreases as time elapses since their last cigarette.

22 Sep 2015

Scientists uncover how embryonic stem cells inhibit virus expression

Scientists from the Institute of Molecular and Cell Biology, a research institute under the Agency for Science, Technology and Research, Singapore, have uncovered the mechanisms which embryonic stem cells employ to inhibit virus expression.

22 Sep 2015

Protein-based modular system could help detect viral infection or kill cancer cells

MIT biological engineers have developed a modular system of proteins that can detect a particular DNA sequence in a cell and then trigger a specific response, such as cell death.

22 Sep 2015

Targeting physical activity is not the effective way to reduce prolonged sitting

Targeting sitting time, rather than physical activity, is the most effective way to reduce prolonged sitting, according to the first comprehensive review of strategies designed to reduce sitting time. The research, led by the Institute of Psychiatry, Psychology & Neuroscience at King's College London, is published in the journal Health Psychology Review.

22 Sep 2015

Study identifies link between kidney stones in children and atherosclerosis

A recent study published in The Journal of Pediatrics is the first to examine and identify a link between kidney stones in children and thickened or hardened arteries — precursors to a wide variety of cardiovascular diseases. Understanding the connection between kidney stones and cardiovascular risk factors in children may help physicians and parents implement prevention measures to reduce future risk of stroke, heart attack or other forms of vascular disease for affected children.

21 Sep 2015

Invitae launches new education program to increase awareness of genetic testing for hereditary cancer

A new survey released today shows 73 percent of Americans are aware of genetic testing for hereditary cancers – a significant increase over just a few years ago. Previous research found that in 2010 less than half of the Americans surveyed said they were aware of genetic testing. Dubbed the "Angelina Jolie Effect," the current data highlight the far-reaching impact of Angelina Jolie's public discussion of genetic testing for hereditary cancer.

21 Sep 2015

Using deep learning to analyze genetic mutations: an interview with Brendan Frey

To understand deep learning in the context of genetic disease, you need to understand shallow learning first. Shallow learning relates mutations to diseases by looking for mutations that commonly occur in patients with a disease. It’s a commonly used method.

21 Sep 2015

Higher doses of hydrocortisone not linked to neurodevelopmental impairments in low birth weight infants

Hydrocortisone is one of the 15 most frequently prescribed medications in extremely low birth weight (?1000 g) infants in the newborn intensive care unit (NICU).

21 Sep 2015

Abnormal behaviour of BDNF and DTNBP1 genes linked to underlying cause of schizophrenia

Research led by scientists from Duke-NUS Graduate Medical School Singapore (Duke-NUS) has linked the abnormal behaviour of two genes (BDNF and DTNBP1) to the underlying cause of schizophrenia. These findings have provided a new target for schizophrenia treatment.

21 Sep 2015

New study finds link between maternal protein deficiency during pregnancy and metabolic diseases in offspring

A new study has uncovered the genetic processes that link insufficient protein consumption during pregnancy with the development of muscle problems in mothers and their male offspring.

19 Sep 2015

Olfactory function may inform Parkinson’s prognosis

Olfactory function is preserved in about a quarter of patients with Parkinson’s disease, and may be predictive of disease course, say researchers.

18 Sep 2015

Manchester researchers reveal why ER+ breast cancer women develop resistance to hormone therapy

University of Manchester researchers funded by Breast Cancer Now have discovered a new explanation as to why women with oestrogen receptor positive (ER+) breast cancer develop resistance to hormone treatment, and a potential new approach to overcome the problem.

18 Sep 2015

Cattle virus found in human cancer cells

Evidence of exposure to bovine leukaemia virus (BLV) has been found in human breast cancer samples. This is the first suggestion of a possible link between infection with a leukaemia virus prevalent in cows and breast cancer in humans.

18 Sep 2015

Genetically engineered vaccine eradicates precancerous cervical lesions

Scientists have used a genetically engineered vaccine to successfully eradicate high-grade precancerous cervical lesions in nearly one-half of women who received the vaccine in a clinical trial. The goal, say the scientists, was to find nonsurgical ways to treat precancerous lesions caused by HPV.

18 Sep 2015

Obese patients with type 2 diabetes should be prioritised for obesity surgery over those without diabetes

New research published in The Lancet Diabetes & Endocrinology suggests that, when considering overall costs of healthcare, obese patients with type 2 diabetes, especially those with recent disease onset, should be prioritised for obesity surgery over those without type 2 diabetes, since many patients see a reversal of diabetes after surgery and thus need fewer expensive diabetes medications or treatment for complications in future.

18 Sep 2015

X linked News and Research

Reduced conflict-related brain activity linked to higher risk for psychosis

Subtle differences in brain function make women react differently to negative emotions, shows research

Gene study reveals how a strain of E. coli evolved to become potentially fatal infection

UCI scientists find potential biomarker for diagnosing certain forms of autism

Bisphosphonate drugs linked to greater risk of atypical hip fractures

Type 2 diabetes risk grows with active and passive smoking

Scientists uncover how embryonic stem cells inhibit virus expression

Protein-based modular system could help detect viral infection or kill cancer cells

Targeting physical activity is not the effective way to reduce prolonged sitting

Study identifies link between kidney stones in children and atherosclerosis

Invitae launches new education program to increase awareness of genetic testing for hereditary cancer

Using deep learning to analyze genetic mutations: an interview with Brendan Frey

Higher doses of hydrocortisone not linked to neurodevelopmental impairments in low birth weight infants

Abnormal behaviour of BDNF and DTNBP1 genes linked to underlying cause of schizophrenia

New study finds link between maternal protein deficiency during pregnancy and metabolic diseases in offspring

Olfactory function may inform Parkinson’s prognosis

Manchester researchers reveal why ER+ breast cancer women develop resistance to hormone therapy

Cattle virus found in human cancer cells

Genetically engineered vaccine eradicates precancerous cervical lesions

Obese patients with type 2 diabetes should be prioritised for obesity surgery over those without diabetes

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