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Orthopedists should suspect necrotizing fasciitis in patients with out of proportion pain

Dr. Russell Russo, an Orthopedic Surgeon at LSU Health Sciences Center New Orleans, and other researchers stress that orthopedists should have a high index of suspicion for necrotizing fasciitis, or flesh-eating bacterial infection, in every patient with pain or other symptoms that are out of proportion to the initial diagnosis. Their recommendations are published in the September 2012 issue of Orthopedics Today.

17 Sep 2012

Anthera to initiate blisibimod Phase 3 program for systemic lupus erythematosus

Anthera Pharmaceuticals, Inc., a biopharmaceutical company developing drugs to treat serious diseases associated with inflammation and autoimmune disorders, today provided an update on regulatory discussions for the global development of blisibimod.

17 Sep 2012

vasopharm's explorative phase IIa NOSTRA trial in TBI meets clinical endpoints for safety

vasopharm GmbH, a pharmaceutical company dedicated to the discovery and development of novel therapeutics for the treatment of cerebro- and cardiovascular diseases, today announces that the explorative phase IIa NOSTRA trial in Traumatic Brain Injury Patients met all clinical endpoints for safety and in addition demonstrated strong evidence of clinical benefit in patients.

17 Sep 2012

Limited positive effect of Tafamidis in neurological disorders

Tafamidis meglumine was approved in November 2011 for the treatment of transthyretin amyloidosis in adults.

17 Sep 2012

Natural antibiotic to treat tuberculosis

A natural product secreted by a soil bacterium shows promise as a new drug to treat tuberculosis report scientists in a new study published in EMBO Molecular Medicine. A team of scientists working in Switzerland has shown how pyridomycin, a natural antibiotic produced by the bacterium Dactylosporangium fulvum, works.

17 Sep 2012

Researchers investigate African plants effective in treating snakebite

A PhD student at the University of Copenhagen has drawn on nature's own pharmacy to help improve the treatment of snakebites in Africa.

17 Sep 2012

Novel drug combination for patients with NRAS-mutant melanoma

A new study published online in Nature Medicine, led by scientists at The University of Texas MD Anderson Cancer Center, describes the discovery of a novel drug combination aimed at a subset of melanoma patients who currently have no effective therapeutic options.

17 Sep 2012

Risks of antidiabetic drug substantially overrated for patients with reduced kidney function

The antidiabetic drug metformin is not prescribed for patients with reduced kidney function because the risk of adverse effects has been regarded as unacceptably high. A study at Sahlgrenska Academy, University of Gothenburg, Sweden, has found that the risks have been substantially overrated. As a result, many more patients with diabetes may be able to enjoy the benefits of the medication.

17 Sep 2012

Drug-resistant tuberculosis: an interview with Sven Hoffner

In contrast to drug-susceptible tuberculosis, which can be cured with available drug therapies, drug-resistant, and especially multi-drug resistant, tuberculosis is much more difficult to cure and it takes a much longer time for patients to become non-infectious.

17 Sep 2012

Scientists describe how natural selection occurs at the cellular level

Scientists from the Spanish National Cancer Research Centre (CNIO) describe how natural selection also occurs at the cellular level, and how our body's tissues and organs strive to retain the best cells in their ranks in order to fend off disease processes.

15 Sep 2012

Alzheimer's pathology might be increased in patients after surgery and anesthesia

A syndrome called "post-operative cognitive decline" has been coined to refer to the commonly reported loss of cognitive abilities, usually in older adults, in the days to weeks after surgery. In fact, some patients time the onset of their Alzheimer's disease symptoms from a surgical procedure.

15 Sep 2012

Study could reveal whether breast cancer patients with BRCA mutations are responsive to Veliparib

Ongoing research at the Methodist Cancer Center could reveal whether metastatic breast cancer patients with BRCA gene mutations are particularly responsive to a drug regimen that includes Veliparib, an investigational drug believed to hamper cancer cells.

15 Sep 2012

MIT engineers use ultrasound waves to enhance permeability of skin to drugs

Using ultrasound waves, MIT engineers have found a way to enhance the permeability of skin to drugs, making transdermal drug delivery more efficient. This technology could pave the way for noninvasive drug delivery or needle-free vaccinations, according to the researchers.

15 Sep 2012

Biomedical scientists identify set of genes essential for A. baumannii gram-negative bacteria

Biomedical scientists collaborating on translational research at two Buffalo institutions are reporting the discovery of a novel, and heretofore unrecognized, set of genes essential for the growth of potentially lethal, drug-resistant bacteria.

15 Sep 2012

Research roundup: Patients' experiences at safety-net hospitals

Each week KHN reporter Ankita Rao compiles a selection of recently released health policy studies and briefs.

15 Sep 2012

Global Fund board members discuss new funding allocation model amid some concerns from TB advocates

The board of the Global Fund to Fight AIDS, Tuberculosis and Malaria began a two-day meeting in Geneva on Thursday, "with one topic high on the agenda: a new funding model," Devex's "Development Newswire" reports.

15 Sep 2012

U.K. scientists develop new test to catch drugs-cheats in sport

Scientists from three UK universities have developed a new test to catch drugs-cheats in sport.

15 Sep 2012

FDA approves Lannett’s ANDA for Butalbital, Acetaminophen and Caffeine Tablets

Lannett Company, Inc. today announced that it has received approval from the U.S. Food and Drug Administration (FDA) of its Abbreviated New Drug Application (ANDA) for Butalbital, Acetaminophen and Caffeine Tablets, USP, 50mg/325mg/40mg.

15 Sep 2012

CINJ experts available to discuss prevention and treatment of breast cancer

The Cancer Institute of New Jersey (CINJ) is making experts available to discuss the risks, and options for treatment and prevention surrounding breast cancer. According to the American Cancer Society 227,000 women nationwide will be diagnosed with the disease this year, and while the disease affects mostly women, men also can be diagnosed with breast cancer.

15 Sep 2012

Study estimates drug concentrations of Truvada and tenofovir to reduce risk of HIV among MSM

Several large clinical trials have demonstrated that a daily oral dose of one or two antiretroviral drugs used to treat HIV infection can prevent infection in an approach known as pre-exposure prophylaxis, or PrEP.

15 Sep 2012

Drugs News and Research

Orthopedists should suspect necrotizing fasciitis in patients with out of proportion pain

Anthera to initiate blisibimod Phase 3 program for systemic lupus erythematosus

vasopharm's explorative phase IIa NOSTRA trial in TBI meets clinical endpoints for safety

Limited positive effect of Tafamidis in neurological disorders

Natural antibiotic to treat tuberculosis

Researchers investigate African plants effective in treating snakebite

Novel drug combination for patients with NRAS-mutant melanoma

Risks of antidiabetic drug substantially overrated for patients with reduced kidney function

Drug-resistant tuberculosis: an interview with Sven Hoffner

Scientists describe how natural selection occurs at the cellular level

Alzheimer's pathology might be increased in patients after surgery and anesthesia

Study could reveal whether breast cancer patients with BRCA mutations are responsive to Veliparib

MIT engineers use ultrasound waves to enhance permeability of skin to drugs

Biomedical scientists identify set of genes essential for A. baumannii gram-negative bacteria

Research roundup: Patients' experiences at safety-net hospitals

Global Fund board members discuss new funding allocation model amid some concerns from TB advocates

U.K. scientists develop new test to catch drugs-cheats in sport

FDA approves Lannett’s ANDA for Butalbital, Acetaminophen and Caffeine Tablets

CINJ experts available to discuss prevention and treatment of breast cancer

Study estimates drug concentrations of Truvada and tenofovir to reduce risk of HIV among MSM

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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