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Scientists develop novel antimicrobials to tackle multidrug-resistant bacteria

Scientists at the University of Surrey in collaboration with research partners at the University of Sheffield and University of Würzburg, Germany, have developed novel antimicrobials, which could be used to treat infections, caused by multidrug-resistant bacteria.

23 Oct 2017

Systematic review finds lack of data on medical cannabis use in children and adolescents

A systematic review of published studies on the use of medical cannabis in children and adolescents finds a notable lack of studies and a minimal number of the randomized, controlled trials needed to confirm the effectiveness of a treatment.

23 Oct 2017

Pharmacological stimulation of nicotinic receptor could be strategy to treat lung inflammation

It has been amply proven that smoking can cause serious diseases such as emphysema and cancer. A new study, however, shows that pharmacological stimulation of a specific type of nicotinic receptor in cells of the immune system could be a strategy to treat inflammatory lung disease.

20 Oct 2017

Liver cancers linked to compound popular in herbal remedies

A latest study has shown that Aristolochic Acids (AA) – that are commonly used as a natural product found in some natural remedies, could be associated with liver cancers. Researchers from Singapore and Taiwan showed in their study that AA could be causing mutations in the genes that predispose an individual to liver cancers.

19 Oct 2017

Arsenic trioxide could be powerful therapy to extend lives of certain glioblastoma patients

From Sherlock Holmes to Agatha Christie, arsenic is often the poison of choice in popular whodunits. But in ultra-low dosage, and in the right form, this naturally occurring chemical element can be a potent force against cancer.

17 Oct 2017

Study opens door to new approach for curing HIV infections

In findings that open the door to a completely different approach to curing HIV infections, scientists from the Florida campus of The Scripps Research Institute have for the first time shown that a novel compound effectively suppresses production of the virus in chronically infected cells, and prevents viral rebound, even when those infected cells are subjected to vigorous stimulation.

17 Oct 2017

Synthetic compound targets enzyme that supports survival and dissemination of metastatic cells

Cancer can most often be successfully treated when confined to one organ. But a greater challenge lies in treating cancer that has metastasized, or spread, from the primary tumor throughout the patient's body.

17 Oct 2017

Dietary combination transforms lethal breast cancers into highly treatable form

Researchers at the University of Alabama at Birmingham have found a dietary combination that transforms the most lethal of all breast cancers into a highly treatable breast cancer.

17 Oct 2017

TSRI scientists develop molecular model for improving design of osteoporosis treatments

Using advanced mass spectrometry technology, scientists from the Florida campus of The Scripps Research Institute have developed a molecular model that may provide a new framework for improving the design of osteoporosis treatments.

13 Oct 2017

Phase 3 clinical trial for compound that shows promise in treatment of Rett syndrome

Rettsyndrome.org is pleased to share that Neuren Pharmaceuticals, today, after meeting with the FDA, will conduct a Phase 3 clinical trial for trofinetide, a compound that shows great promise in the treatment of Rett syndrome, in children and adults.

13 Oct 2017

Magic mushrooms may effectively reset activity of brain circuits involved in depression

Patients taking psilocybin to treat depression show reduced symptoms weeks after treatment following a 'reset' of their brain activity.

13 Oct 2017

Researchers find potential approach to prevent peripheral neuropathy

In discovering how certain chemotherapy drugs cause the nerve damage known as peripheral neuropathy, researchers at Dana-Farber Cancer Institute have found a potential approach to preventing this common and troublesome side effect of cancer treatment.

11 Oct 2017

Allergy medication restores nervous system function in patients with chronic MS

In a remarkably rapid translation of laboratory research findings into a treatment with the potential to benefit patients, UC San Francisco scientists have successfully completed a Phase II clinical trial showing that an FDA-approved antihistamine restores nervous system function in patients with chronic multiple sclerosis (MS).

11 Oct 2017

TB Alliance announces phase 1 clinical trials of two novel tuberculosis drugs

TBA-7371 and sutezolid entered phase 1 clinical trials, TB Alliance announced today. Both compounds have proceeded through early preclinical development and were granted "Investigative New Drug" status by the U.S. Food and Drug Administration. The phase 1 clinical trials are presently ongoing.

11 Oct 2017

Newly discovered compound causes cancer cell death, whilst sparing healthy cells

Researchers have discovered a compound that can trigger cancer cells to self-destruct, without causing any damage to healthy cells.

10 Oct 2017

Human minibrains expose psychedelic drug effects, study reveals

A Brazilian study has detected variations in signaling pathways that are associated with neurodegeneration, inflammation, and neural plasticity stimulated by a compound from the dimethyltryptamine family known as 5-MeO-DMT.

10 Oct 2017

New treatment approach makes cancer cells commit suicide while sparing healthy cells

Scientists at Albert Einstein College of Medicine have discovered the first compound that directly makes cancer cells commit suicide while sparing healthy cells.

9 Oct 2017

Study unveils neuronal effects of psychedelics using cerebral organoids

A Brazilian study, published in Scientific Reports on October 09, 2017, has identified changes in signaling pathways associated with neural plasticity, inflammation and neurodegeneration triggered by a compound from the family of dimethyltryptamine known as 5-MeO-DMT.

9 Oct 2017

New antifungal drug developed to help in treatment of invasive fungal infections

University of Liverpool researchers, working with F2G Limited (Eccles, Manchester), have developed a new antifungal drug to help in the treatment of life threatening invasive fungal infections such as invasive aspergillosis.

6 Oct 2017

Researchers uncover promising targets for development of drugs against leishmaniasis

Brazilian researchers at the University of São Paulo's Bioscience Institute (IB-USP) are starting to unravel the molecular mechanisms by which the parasite that causes cutaneous leishmaniasis manages to circumvent the host organism's defenses and infect new cells.

5 Oct 2017

Compound News and Research

Scientists develop novel antimicrobials to tackle multidrug-resistant bacteria

Systematic review finds lack of data on medical cannabis use in children and adolescents

Pharmacological stimulation of nicotinic receptor could be strategy to treat lung inflammation

Liver cancers linked to compound popular in herbal remedies

Arsenic trioxide could be powerful therapy to extend lives of certain glioblastoma patients

Study opens door to new approach for curing HIV infections

Synthetic compound targets enzyme that supports survival and dissemination of metastatic cells

Dietary combination transforms lethal breast cancers into highly treatable form

TSRI scientists develop molecular model for improving design of osteoporosis treatments

Phase 3 clinical trial for compound that shows promise in treatment of Rett syndrome

Magic mushrooms may effectively reset activity of brain circuits involved in depression

Researchers find potential approach to prevent peripheral neuropathy

Allergy medication restores nervous system function in patients with chronic MS

TB Alliance announces phase 1 clinical trials of two novel tuberculosis drugs

Newly discovered compound causes cancer cell death, whilst sparing healthy cells

Human minibrains expose psychedelic drug effects, study reveals

New treatment approach makes cancer cells commit suicide while sparing healthy cells

Study unveils neuronal effects of psychedelics using cerebral organoids

New antifungal drug developed to help in treatment of invasive fungal infections

Researchers uncover promising targets for development of drugs against leishmaniasis

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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