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Alzheimer's disease may damage brain

Alzheimer's disease has long been studied primarily as a disease of neurons. But researchers have now shown how the disease may be damaging the brain by choking off blood flow. In experiments published June 10 in Neuron, scientists at Rockefeller University reveal that amyloid-β, which builds up around brain cells in Alzheimer's patients, interacts with a common blood clotting agent to increase clotting in the arteries that feed the brain.

17 Jun 2010

Research studies may lead to future development of cell transplant therapy for ALS

The University of California, San Diego, The Salk Institute for Biological Studies and Life Technologies Corporation today announced the initiation of studies which may lead to the future development of cell transplant therapy for amyotrophic lateral sclerosis, also known as Lou Gehrig's disease. Currently, there is only one FDA-approved pharmaceutical addressing this lethal disease, which affects approximately 30,000 people in the United States.

17 Jun 2010

Florida State University researcher explores role of key protein in cell division

A Florida State University researcher has identified the important role that a key protein plays in cell division, and that discovery could lead to a greater understanding of stem cells.

16 Jun 2010

New research shows astrocytes play important role in the function of nerve cells

Astrocytes are the most common type of cell in the brain and play an important role in the function of neurons - nerve cells. New research from the University of Gothenburg, Sweden, shows that they are also directly involved in the regulation of signalling between neurons.

15 Jun 2010

Astrocytes involved in regulation of signalling between neurons: Study

14 Jun 2010

Research may lead to better treatments for depression and substance abuse

In what has been hailed as a breakthrough, scientists from Columbia University Medical Center and Weill Cornell Medical College have outlined the molecular mechanism of membrane transport. The research shows how a protein transforms its shape to transport substances across the cell membrane in order to regulate transmission of the brain's messages across the synaptic gap from one neuron to another.

11 Jun 2010

Neutralizing inhibitory molecules does not improve regeneration in damaged spinal axons

Neuroscientists at the University of California, San Diego School of Medicine have found that removing three key inhibitory molecules from myelin - the insulating material that surrounds nerve cell fibers - does not significantly boost the ability of injured spinal axons to regenerate and restore themselves to full function.

10 Jun 2010

Brain stimulation with ultrasound may enhance cognitive function

The ability to diagnose and treat brain dysfunction without surgery, may rely on a new method of noninvasive brain stimulation using pulsed ultrasound developed by a team of scientists led by William "Jamie" Tyler, a neuroscientist at Arizona State University. The approach, published in the journal Neuron on June 9, shows that pulsed ultrasound not only stimulates action potentials in intact motor cortex in mice but it also "elicits motor responses comparable to those only previously achieved with implanted electrodes and related techniques," says Yusuf Tufail, the lead author from ASU's School of Life Sciences.

10 Jun 2010

Mutations in ion channels cause rare inherited pain disorder: Research

A mutation that enhances the function of a specific ion channel has been identified as the cause of a rare inherited pain disorder. The research, published by Cell Press in the June 10 issue of the journal Neuron, proposes a potential treatment for the disorder and may lead to a better understanding of chronic pain in humans.

10 Jun 2010

Novel gene replacement therapy holds promise for Spinal Muscular Atrophy

Children who suffer from the devastating disease Spinal Muscular Atrophy are set to benefit from a new breakthrough in therapy developments by researchers at the University of Sheffield.

10 Jun 2010

Abnormalities in the process of blood clot formation contribute to pathogenesis of AD: Research

New research suggests that abnormalities in the process of blood clot formation may contribute to the pathogenesis of Alzheimer's disease. The study, published by Cell Press in the June 10 issue of the journal Neuron, advances our understanding of the link between vascular pathology and AD and proposes a new therapeutic strategy aimed at slowing cognitive decline.

10 Jun 2010

Intellect Neurosciences receives Notice of Allowance from Israeli patent office for OXIGON drug candidate

Intellect Neurosciences, Inc announced it has received a Notice of Allowance from the Israeli Patent and Trademark Office for a new patent related to the Company's clinical-stage drug candidate OX1 (OXIGON), which has disease-modifying potential for Alzheimer's and other neurodegenerative disorders.

9 Jun 2010

Repligen's fiscal 2010 total revenue decreases to $20,971,000

Repligen Corporation today reported results for the fourth quarter and fiscal year 2010, ended March 31, 2010. Total revenue for the year was $20,971,000 compared to total revenue of $29,362,000 for fiscal year 2009 ended March 31, 2009.

9 Jun 2010

Pecans may delay progression of age-related motor neuron degeneration: Study

Eating about a handful of pecans each day may play a role in protecting the nervous system, according to a new animal study published in the current issue of Current Topics in Nutraceutical Research. The study, conducted at the Center for Cellular Neurobiology at the University of Massachusetts Lowell, suggests adding pecans to your diet may delay the progression of age-related motor neuron degeneration. This may include diseases like amyotropic lateral sclerosis (ALS), also known as Lou Gehrig's Disease.

9 Jun 2010

Nutrient found in maternal diet provide lasting cognitive, emotional benefits to people with Down syndrome: Study

A nutrient found in egg yolks, liver and cauliflower taken by mothers during pregnancy and nursing may offer lifelong "dramatic" health benefits to people with Down syndrome.

4 Jun 2010

Sound repetition helps memorize complex sounds

Sound repetition allows us to memorize complex sounds in a very quick, effective and durable way. This form of auditory learning, which was evidenced for the first time by researchers from CNRS, ENS Paris, and Paris Descartes and Toulouse 3 universities, is believed to occur in daily life to help us identify and memorize sound patterns; it allows, for example, immediate recognition of sounds which become familiar through experience, such as the voice of relatives.

1 Jun 2010

Researchers identify body's natural self-repair mechanism that kicks in after spinal-cord injury

Researchers in the University of Alberta's Faculty of Rehabilitation Medicine have made an important discovery that could lead to more effective treatments for spinal-cord injuries. Karim Fouad and David Bennett have identified one of the body's natural self-repair mechanisms that kick in after injury.

31 May 2010

Scientists study interaction between Notch signaling pathway and BCL6 gene to understand how cancer forms

A Florida State University College of Medicine researcher has discovered a new interaction between a cell signaling system and a specific gene that may be the cause of B-cell lymphoma. The finding suggests a similar interaction could be occurring during the development of other types of cancer, leading to further understanding of how cancer works — and how it might be stopped.

28 May 2010

Bone marrow transplant cures excessive pathological grooming behavior in mice

Scientists earlier found that mice missing one of a group of core developmental genes known as the Hox genes developed an odd and rather unexpected pathology: the mutant animals groomed themselves compulsively to the point that they were removing their own hair and leaving self-inflicted open sores on their skin. Now, they've found a surprising connection between the Hoxb8 gene and the behavior that looks an awful lot like that of people with an obsessive compulsive spectrum disorder (OCD).

28 May 2010

UCSF scientists discover new stem cell in developing human brain

UCSF scientists have discovered a new stem cell in the developing human brain. The cell produces nerve cells that help form the neocortex - the site of higher cognitive function -- and likely accounts for the dramatic expansion of the region in the lineages that lead to man, the researchers say.

26 May 2010

Neuron News and Research

Alzheimer's disease may damage brain

Research studies may lead to future development of cell transplant therapy for ALS

Florida State University researcher explores role of key protein in cell division

New research shows astrocytes play important role in the function of nerve cells

Astrocytes involved in regulation of signalling between neurons: Study

Research may lead to better treatments for depression and substance abuse

Neutralizing inhibitory molecules does not improve regeneration in damaged spinal axons

Brain stimulation with ultrasound may enhance cognitive function

Mutations in ion channels cause rare inherited pain disorder: Research

Novel gene replacement therapy holds promise for Spinal Muscular Atrophy

Abnormalities in the process of blood clot formation contribute to pathogenesis of AD: Research

Intellect Neurosciences receives Notice of Allowance from Israeli patent office for OXIGON drug candidate

Repligen's fiscal 2010 total revenue decreases to $20,971,000

Pecans may delay progression of age-related motor neuron degeneration: Study

Nutrient found in maternal diet provide lasting cognitive, emotional benefits to people with Down syndrome: Study

Sound repetition helps memorize complex sounds

Researchers identify body's natural self-repair mechanism that kicks in after spinal-cord injury

Scientists study interaction between Notch signaling pathway and BCL6 gene to understand how cancer forms

Bone marrow transplant cures excessive pathological grooming behavior in mice

UCSF scientists discover new stem cell in developing human brain

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