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Weill Cornell Medical College receives three new research grants for translational blood cancer study

Weill Cornell Medical College has been awarded three new research grants from the Leukemia & Lymphoma Society totaling $1.8 million. The funds will support critically-needed translational research for blood cancers, accelerating promising discoveries from the laboratory to the patient's bedside.

31 Aug 2012

Impulsive and compulsive personality traits linked with traumatic upbringing during childhood

Previous research has shown that personality traits such as impulsivity or compulsiveness are indicators of an increased risk of addiction. Now, new research from the University of Cambridge suggests that these impulsive and compulsive personality traits are also associated with a traumatic upbringing during childhood.

31 Aug 2012

Studies examine how PML gene regulates the fatty acid oxidation pathway

Two papers led by scientific teams from the Cancer Genetics Program at Beth Israel Deaconess Medical Center (BIDMC) shed new light on the genetic mechanisms underlying cellular energy and metabolism and, at the same time, highlight both the challenges and opportunities of genetic approaches to cancer treatment.

31 Aug 2012

Scientists open new front against cause of sleeping sickness

Scientists of the Antwerp Institute of Tropical Medicine (ITG) opened a new front against the cause of sleeping sickness. This parasite is transmitted between humans by tsetse flies. The researchers learned a bacterium living in those flies how to produce antibodies against the parasite. Application in the field is still a long way of, but the technique shows quite some promise.

31 Aug 2012

PD0325901 drug may hold potential to prevent neurofibromatosis 1 in children

A drug originally developed to stop cancerous tumors may hold the potential to prevent abnormal brain cell growth and learning disabilities in some children, if they can be diagnosed early enough, a new animal study suggests.

31 Aug 2012

Roundup: Brown's pension plan no panacea for Calif.; Personhood amendment won't make Colo. ballot

Even by the most ambitious forecasts, the plan Gov. Jerry Brown and fellow Democrats are championing to contain government worker pensions in California could leave state taxpayers awash in debt to public employees.

31 Aug 2012

Early cannabis use damages developing brain

Persistent use of cannabis before the age of 18 years can lead to lowered intelligence, attention, and memory in adulthood, show results published in the Proceedings of the National Academy of Sciences.

30 Aug 2012

Chronic nerve pain: an interview with Professor Sally Lawson

Chronic nerve pain results from pathological changes within a nerve that appear to be self-sustaining and thus the pain continues for a long time.

30 Aug 2012

Drug-resistant tuberculosis levels described as alarming by international study

A large, international study published Online First in The Lancet reveals alarming levels of tuberculosis (TB) that are resistant to both first-line and second-line drugs. The findings show high prevalence of resistance to at least one second-line drug (43.7%) among multidrug-resistant (MDR) TB patients from eight countries in Africa, Asia, Europe, and Latin America. Worse still, the study found higher than expected overall levels of extensively drug-resistant (XDR) TB.

30 Aug 2012

UAB Center of Research Translation to improve health of patients with gout, hyperuricemia

The University of Alabama at Birmingham is establishing a Center of Research Translation to improve the health of an increasing number of patients with gout and hyperuricemia.

30 Aug 2012

MU medicinal chemists create more potent, efficient weapon against cancer

Legend has it that Ralph Waldo Emerson once said, "Build a better mousetrap, and the world will beat a path to your door." University of Missouri researchers are doing just that, but instead of building mousetraps, the scientists are targeting cancer drugs. In a new study, MU medicinal chemists have taken an existing drug that is being developed for use in fighting certain types of cancer, added a special structure to it, and created a more potent, efficient weapon against cancer.

30 Aug 2012

IQWiG examines added benefit of belimumab for patients with systemic lupus erythematosus

Belimumab has been approved since July 2011 as an add-on therapy for adult patients with the autoimmune disease systemic lupus erythematosus (SLE). Products (AMNOG).

30 Aug 2012

India's contribution to global health R&D needs domestic, international support

As the BRIC countries -- Brazil, Russia, India, and China -- invest more in innovations in health technologies and other areas, "many are looking to these countries to correct the global health research and development (R&D) imbalance that leaves the poor without needed products such as an improved tuberculosis (TB) vaccine or tests to help diagnose patients in remote rural settings," David de Ferranti, president of Results for Development Institute (R4D), writes in the Huffington Post Blog.

30 Aug 2012

UH pharmacologist examines age-related oxidative, inflammatory stress

Gaining new insight to managing sodium balance and blood pressure, investigators at the University of Houston (UH) College of Pharmacy believe their work may identify future therapeutic targets to control hypertension.

30 Aug 2012

GWSMHS professor to study correlation between genetics and susceptibility to drug abuse

Norman H. Lee, Ph.D., professor of pharmacology at the George Washington University School of Medicine and Health Sciences (SMHS), received a total of $405,001 in grant funding from the National Institute on Drug Abuse (NIDA) to continue to study the correlation between genetics and susceptibility to drug abuse.

30 Aug 2012

Sri Lanka succeeds in reducing malaria cases by 99.9% since 1999

Despite nearly three decades of conflict, Sri Lanka has succeeded in reducing malaria cases by 99.9 percent since 1999 and is on track to eliminate the disease entirely by 2014.

30 Aug 2012

Protalex announces results from PRTX-100 Phase 1b trial on active rheumatoid arthritis

Protalex, Inc., a clinical stage biopharmaceutical company focused on the development of a class of drugs designed to treat autoimmune and inflammatory diseases including rheumatoid arthritis (RA), today announced results from its recently completed Phase 1b randomized, multiple-dose, dose-escalation study.

30 Aug 2012

Sicor Biotech receives FDA approval for tbo-filgrastim to treat severe neutropenia

The U.S. Food and Drug Administration today approved Sicor Biotech's tbo-filgrastim to reduce the time certain patients receiving cancer chemotherapy experience severe neutropenia, a decrease in infection-fighting white blood cells called neutrophils.

30 Aug 2012

FDA grants orphan designation to Aerial BioPharma’s ARL-N05 for treatment of narcolepsy

Aerial BioPharma, a biopharmaceutical company focused on developing biologics and small molecules for conditions in the central nervous system, has received orphan drug designation for its narcolepsy drug in development.

30 Aug 2012

Novartis receives FDA approval for Afinitor Disperz to treat subependymal giant cell astrocytoma

The U.S. Food and Drug Administration today approved Afinitor Disperz (everolimus tablets for oral suspension), a new pediatric dosage form of the anti-cancer drug Afinitor (everolimus) used to treat a rare brain tumor called subependymal giant cell astrocytoma.

30 Aug 2012

Drugs News and Research

Weill Cornell Medical College receives three new research grants for translational blood cancer study

Impulsive and compulsive personality traits linked with traumatic upbringing during childhood

Studies examine how PML gene regulates the fatty acid oxidation pathway

Scientists open new front against cause of sleeping sickness

PD0325901 drug may hold potential to prevent neurofibromatosis 1 in children

Roundup: Brown's pension plan no panacea for Calif.; Personhood amendment won't make Colo. ballot

Early cannabis use damages developing brain

Chronic nerve pain: an interview with Professor Sally Lawson

Drug-resistant tuberculosis levels described as alarming by international study

UAB Center of Research Translation to improve health of patients with gout, hyperuricemia

MU medicinal chemists create more potent, efficient weapon against cancer

IQWiG examines added benefit of belimumab for patients with systemic lupus erythematosus

India's contribution to global health R&D needs domestic, international support

UH pharmacologist examines age-related oxidative, inflammatory stress

GWSMHS professor to study correlation between genetics and susceptibility to drug abuse

Sri Lanka succeeds in reducing malaria cases by 99.9% since 1999

Protalex announces results from PRTX-100 Phase 1b trial on active rheumatoid arthritis

Sicor Biotech receives FDA approval for tbo-filgrastim to treat severe neutropenia

FDA grants orphan designation to Aerial BioPharma’s ARL-N05 for treatment of narcolepsy

Novartis receives FDA approval for Afinitor Disperz to treat subependymal giant cell astrocytoma

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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