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Roundup: Calif. Gov. Brown's pension plan silent on current workers' health care; Psychologists want power to prescribe drugs

Gov. Jerry Brown announced a new plan Tuesday to rein in public pension costs that would raise the retirement age, cap benefits for the highest-paid employees and eliminate "spiking" -- but lacks key parts of the bolder system overhaul he proposed months ago and would even increase some payouts. ... The plan also does not address skyrocketing health care costs for retirees, another main element of the governor's first scenario. Hundreds of thousands of government workers have been promised medical coverage for life.

30 Aug 2012

Vitamin to the rescue in fight with ‘superbugs’

High doses of vitamin B3 may help fight against so called “superbugs” such as methicillin-resistant Staphylococcus aureus, show study results.

29 Aug 2012

Sleep disorder treatment: an interview with Dr Seth Lederman, President and CEO of Tonix Pharmaceuticals

Sleep disorders are a large area. We are focused on one particular type of sleep disturbance called “non-restorative” sleep. People with this problem do sleep, but they don’t wake up feeling refreshed or feeling that their sleep has had the restorative effects of healthy sleep.

29 Aug 2012

Omitting aspirin leads to less bleedings but does not increase risk of stent thrombosis, MI

Lifelong anticoagulation is necessary for the prevention of stroke in patients with rhythm disturbances and with mechanical valves. Patients who have a coronary stent implanted also need the antiplatelet drugs aspirin and clopidogrel to prevent the rare but lethal complication of stent thrombosis.

29 Aug 2012

New method simplifies pharmaceutical production of proteins

Engineering researchers at the University of Arkansas have developed a method to simplify the pharmaceutical production of proteins used in drugs that treat a variety of diseases and health conditions, including diabetes, cancer, arthritis and macular degeneration.

29 Aug 2012

Voters need more information on free trade agreement that could impact drug prices

In an opinion piece in the Guardian's "Comment is Free" blog, Dean Baker, co-director of the Center for Economic and Policy Research, discusses potential policies contained within the "Trans-Pacific Partnership Agreement (TPP), a pact that the United States is negotiating with Australia, Canada, Japan and eight other countries in the Pacific region."

29 Aug 2012

Novelos expects to submit CLR1502 IND with FDA for non-invasive tumor imaging

Novelos Therapeutics, Inc., a pharmaceutical company developing novel drugs for the treatment and diagnosis of cancer, today announced that it is developing CLR1502 (GLOW2), a preclinical cancer-targeted optical imaging agent for intraoperative tumor margin illumination and non-invasive tumor imaging.

29 Aug 2012

Risk of stroke after myocardial infarction seems to decrease with improvements in coronary care

The analysis of data from two Swedish registries was presented by Dr Anders Ulvenstam, and suggests that the reduction is due to improvements in AMI care.

29 Aug 2012

Catheter ablation for Afib is safe and suppresses arrhythmia recurrences

Catheter ablation for atrial fibrillation (Afib) is safe and suppresses arrhythmia recurrences in 74% of patients after a single procedure, according to results from the one-year follow-up of the Atrial Fibrillation Ablation Pilot Study, the first European registry to evaluate the real-life epidemiology of catheter ablation for AFib.

29 Aug 2012

MMV390048 shows potent activity against multiple points in malaria parasite's lifecycle

A recently discovered compound from the aminopyridine class not only has the potential to become part of a single-dose cure for all strains of malaria, but might also be able to block transmission of the parasite from person to person, according to a research collaboration involving the Medicines for Malaria Venture (MMV), based in Switzerland, and the Drug Discovery and Development Centre (H3-D) at the University of Cape Town, South Africa.

29 Aug 2012

Scientists identify genes that underlie growth of primitive leukemia stem cells

University of Rochester Medical Center scientists believe they are the first to identify genes that underlie the growth of primitive leukemia stem cells, and then to use the new genetic signature to identify currently available drugs that selectively target the rogue cells.

29 Aug 2012

SPR microscopy examines binding kinetics of membrane proteins

Proteins adorning the surfaces of human cells perform an array of essential functions, including cell signaling, communication and the transport of vital substances into and out of cells. They are critical targets for drug delivery and many proteins are now being identified as disease biomarkers - early warning beacons announcing the pre-symptomatic presence of cancers and other diseases.

29 Aug 2012

Three Pulmatrix PUR118 clinical studies on COPD, asthma to be presented at ERS Annual Congress

Pulmatrix, Inc., a clinical stage biotechnology company creating novel inhaled therapeutics, announced today that three posters on its lead iCALM therapeutic, the first treatment developed utilizing its iSPERSE inhaled drug platform, will be presented at the European Respiratory Society (ERS) Annual Congress taking place September 1-5, 2012, in Vienna, Austria.

28 Aug 2012

Obama, Romney trade more Medicare barbs

President Barack Obama went on the Medicare attack, using his weekly address to challenge Republican charges that he cut Medicare. Obama also launched a new ad saying that the Romney-Ryan ticket would end Medicare as it exists today. But the Romney campaign has Medicare messages of its own.

28 Aug 2012

Global platelet reactivity effectively identifies ACS patients at high risk of ischemic events

Global platelet reactivity is more effective than responsiveness to clopidogrel in identifying acute coronary syndrome (ACS) patients at high risk of ischemic events, according to research presented at the ESC Congress today. The results from the RECLOSE 2-ACS study were presented by Dr Rossella Marcucci from Italy.

28 Aug 2012

Friedreich Ataxia Research Alliance, USF ARC to host ‘Understanding a Cure’ symposium

Scientists, clinicians and patients will gather at the University of South Florida's Center for Advanced Medical Learning and Simulation (CAMLS) in downtown Tampa Sept. 6 to share research insights and energize the search for a cure for Friedreich's ataxia and related disorders.

28 Aug 2012

Renal denervation regenerates blood vessels and could reduce cardiovascular events

Renal denervation improves blood pressure and arterial stiffness in patients with therapy resistant hypertension, according to research presented at ESC Congress 2012 by Mr Klaas Franzen from the University Hospital of Schleswig-Holstein.

28 Aug 2012

Researchers now add electronic sensors to tissue scaffolds

To control the three-dimensional shape of engineered tissue, researchers grow cells on tiny, sponge-like scaffolds. These devices can be implanted into patients or used in the lab to study tissue responses to potential drugs.

28 Aug 2012

Nicotinamide may combat antibiotic-resistance staph infections

A new study suggests that nicotinamide, more commonly known as vitamin B3, may be able to combat some of the antibiotic-resistance staph infections that are increasingly common around the world, have killed thousands and can pose a significant threat to public health.

28 Aug 2012

Personalized antiplatelet treatment leads to better outcomes in patients undergoing PCI

Personalized antiplatelet treatment leads to better outcomes than standard antiplatelet treatment in patients undergoing coronary stent implantation, according to results from the MADONNA study presented at ESC Congress 2012.

28 Aug 2012

Drugs News and Research

Roundup: Calif. Gov. Brown's pension plan silent on current workers' health care; Psychologists want power to prescribe drugs

Vitamin to the rescue in fight with ‘superbugs’

Sleep disorder treatment: an interview with Dr Seth Lederman, President and CEO of Tonix Pharmaceuticals

Omitting aspirin leads to less bleedings but does not increase risk of stent thrombosis, MI

New method simplifies pharmaceutical production of proteins

Voters need more information on free trade agreement that could impact drug prices

Novelos expects to submit CLR1502 IND with FDA for non-invasive tumor imaging

Risk of stroke after myocardial infarction seems to decrease with improvements in coronary care

Catheter ablation for Afib is safe and suppresses arrhythmia recurrences

MMV390048 shows potent activity against multiple points in malaria parasite's lifecycle

Scientists identify genes that underlie growth of primitive leukemia stem cells

SPR microscopy examines binding kinetics of membrane proteins

Three Pulmatrix PUR118 clinical studies on COPD, asthma to be presented at ERS Annual Congress

Obama, Romney trade more Medicare barbs

Global platelet reactivity effectively identifies ACS patients at high risk of ischemic events

Friedreich Ataxia Research Alliance, USF ARC to host ‘Understanding a Cure’ symposium

Renal denervation regenerates blood vessels and could reduce cardiovascular events

Researchers now add electronic sensors to tissue scaffolds

Nicotinamide may combat antibiotic-resistance staph infections

Personalized antiplatelet treatment leads to better outcomes in patients undergoing PCI

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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