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FDA approves Gilead’s Stribild to treat HIV-1 infection

The U.S. Food and Drug Administration today approved Stribild (elvitegravir, cobicistat, emtricitabine, tenofovir disoproxil fumarate), a new once-a-day combination pill to treat HIV-1 infection in adults who have never been treated for HIV infection.

28 Aug 2012

Tris Pharma joins Perrigo to launch first ever store brand ER liquid cough/cold product

Perrigo Company and Tris Pharma, Inc. today announced the commercial launch of a major new store brand product. The new product is equivalent to Delsym extended–release oral liquid suspension containing dextromethorphan polistirex and will be marketed under major U.S. retailer and wholesalers' store brands or own label brands.

27 Aug 2012

Insulin glargine retards progression of atherosclerosis in high-risk people

A sub-study of the Outcome Reduction with an Initial Glargine Intervention (ORIGIN) trial, designed to investigate the effect of insulin glargine and omega-3 fatty acids on atherosclerosis progression, has found that, compared to standard care, only insulin glargine (a long-acting insulin) had a "modest" statistically non-significant reducing effect on the primary outcome of rate of change in maximum carotid intima media thickness (CIMT) at 12 carotid sites.

27 Aug 2012

Renal denervation leads to better outcomes than standard drug treatment in patients with AHF

Renal denervation leads to better outcomes than standard drug treatment in patients with advanced heart failure, according to research presented at ESC Congress 2012. The results of the Olomouc I pilot study were presented by Dr Miloš Táborský from the University Hospital Olomouc.

27 Aug 2012

Oral FluCide drug candidates effective in reducing lung viral load: NanoViricides

NanoViricides, Inc. announced today that anti-influenza drug candidates under its FluCide program, when given orally, were nearly as effective as when administered as IV injections in terms of reduction in lung viral load.

27 Aug 2012

New method helps engineer tissues with embedded nanoscale networks

A multi-institutional research team has developed a method for embedding networks of biocompatible nanoscale wires within engineered tissues. These networks—which mark the first time that electronics and tissue have been truly merged in 3D—allow direct tissue sensing and potentially stimulation, a potential boon for development of engineered tissues that incorporate capabilities for monitoring and stimulation, and of devices for screening new drugs.

27 Aug 2012

Renal denervation improves depression, QOL and stress in patients with resistant hypertension

Renal sympathetic denervation improves anxiety, depression, quality of life and stress in patients with resistant hypertension, according to research presented at ESC Congress 2012 by Dr Denise Fischer from Saarland University Hospital.

27 Aug 2012

Healthy behaviours decrease risk of high blood pressure by two thirds

Healthy behaviours regarding alcohol, physical activity, vegetable intake and body weight reduce the risk of hypertension by two thirds, according to research presented at the ESC Congress today.

27 Aug 2012

IABP does not improve blood pressure symptoms in patients with cardiogenic shock

A balloon pump inserted in the aorta is currently the most widely used support device in the treatment of cardiogenic shock and, since its introduction in 1968, has been used in several million people.

27 Aug 2012

Renal denervation safe and effective in patients with treatment resistant hypertension

Renal denervation leads to significant and sustained blood pressure reduction for up to 18 months in patients with treatment resistant hypertension, according to research presented at ESC Congress 2012.

27 Aug 2012

Debiopharm initiates enrollment in triptorelin phase III study for central precocious puberty

Debiopharm Group (Debiopharm), a Swiss-based global biopharmaceutical group of companies with a focus on the development of prescription drugs that target unmet medical needs and companion diagnostics, today announced that the first patient has been enrolled in an open-label phase III study to investigate the efficacy, safety, and pharmacokinetics of the sustained release triptorelin pamoate 22.5 mg 6-month-formulation in children with central precocious puberty (CPP), a rare disease.

27 Aug 2012

Prasugrel as safe as clopidogrel in preventing heart attack, stroke and death

The first trial to study patients with acute coronary syndrome who do not undergo coronary stenting or bypass surgery found no significant difference between two anti-clotting drugs - prasugrel and clopidogrel - in preventing the first occurrence of death, heart attack or stroke, according to Duke University Medical Center cardiologists.

27 Aug 2012

Obama, Romney exchange barbs on Medicare, abortion

The former Massachusetts governor, responding to charges of a GOP "war on women," says his state health overhaul provided health care for "all women and men." The president, meanwhile, fights back against charges that he is taking money out of Medicare by asserting he wants to strengthen and preverve the program. Both campaigns also debut new ads on Medicare.

27 Aug 2012

Research roundup: Who do patients seek for primary care?; Treating kids with antipsychotics

n order to find out what kind of doctor patients were visiting for primary care service, researchers analyzed the frequency in which patients visited generalists and specialists in 1999 and 2007 by using a nationally representative sample of outpatient visits.

26 Aug 2012

Novira secures $23M in Series A financing to support antiviral development for HBV, HIV

Novira Therapeutics Inc. today announced it has secured $23 million in Series A financing to support the development of its capsid-targeting antivirals for the treatment of chronic hepatitis B (HBV) and HIV infections.

24 Aug 2012

Lilly’s solanezumab Phase 3 trials on AD do not meet primary endpoints

Eli Lilly and Company today announced that the primary endpoints, both cognitive and functional, were not met in either of the two Phase 3, double-blind, placebo-controlled solanezumab EXPEDITION trials in patients with mild-to-moderate Alzheimer's disease.

24 Aug 2012

Herbal plant extract may help cure breast cancer

Scientists at Aston University and Russells Hall Hospital have discovered that an extract from a common plant in Pakistan may help cure breast cancer.

24 Aug 2012

Pre-emptive therapy better than valacyclovir prophylaxis in treating CMV in transplant recipients

Waiting to treat the commonest viral infections in transplant recipients until they reach a certain threshold is better than prophylactically treating all recipients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

24 Aug 2012

Diabetes journal reports results from novel experimental therapy

Results from a novel experimental therapy for Type 1 diabetes that boosts parts of the healthy immune system are reported today in the scientific journal Diabetes.

24 Aug 2012

Researchers discover new way to disarm harmful bacteria

Rather than trying to kill bacteria outright with drugs, Université de Montréal researchers have discovered a way to disarm bacteria that may allow the body's own defense mechanisms to destroy them. "To understand this strategy one could imagine harmful bacteria being like Darth Vader, and the anti-virulence drug would take away his armor and lightsaber," explained Dr. Christian Baron, the study's lead author and Professor at the Department of Biochemistry.

24 Aug 2012

Drugs News and Research

FDA approves Gilead’s Stribild to treat HIV-1 infection

Tris Pharma joins Perrigo to launch first ever store brand ER liquid cough/cold product

Insulin glargine retards progression of atherosclerosis in high-risk people

Renal denervation leads to better outcomes than standard drug treatment in patients with AHF

Oral FluCide drug candidates effective in reducing lung viral load: NanoViricides

New method helps engineer tissues with embedded nanoscale networks

Renal denervation improves depression, QOL and stress in patients with resistant hypertension

Healthy behaviours decrease risk of high blood pressure by two thirds

IABP does not improve blood pressure symptoms in patients with cardiogenic shock

Renal denervation safe and effective in patients with treatment resistant hypertension

Debiopharm initiates enrollment in triptorelin phase III study for central precocious puberty

Prasugrel as safe as clopidogrel in preventing heart attack, stroke and death

Obama, Romney exchange barbs on Medicare, abortion

Research roundup: Who do patients seek for primary care?; Treating kids with antipsychotics

Novira secures $23M in Series A financing to support antiviral development for HBV, HIV

Lilly’s solanezumab Phase 3 trials on AD do not meet primary endpoints

Herbal plant extract may help cure breast cancer

Pre-emptive therapy better than valacyclovir prophylaxis in treating CMV in transplant recipients

Diabetes journal reports results from novel experimental therapy

Researchers discover new way to disarm harmful bacteria

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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