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HIV-related stigma keeps Kenyan pregnant women from having babies in health-care facilities

The fear of being labeled HIV-positive is strong enough to keep mothers in one Kenyan province from having babies in health-care facilities, according to a study published online today in the journal PLOS Medicine. Communities there have come to see clinics and skilled care as mostly for HIV-positive women.

22 Aug 2012

Chemotherapy during pregnancy: an interview with Professor Sibylle Loibl

The incidence is about 1-3% of all breast cancers. The incidence seems to be increasing due to women delaying their childbearing to when they are in their thirties.

22 Aug 2012

International community must redouble efforts to ensure 'many' AIDS-free generations

A Lancet editorial discusses the agenda of the XIX International AIDS Conference (AIDS 2012) in Washington last month and asks how the success of the conference will be judged at the XX International AIDS Conference (AIDS 2014), to be held in Melbourne, Australia.

22 Aug 2012

Brand-name drug makers bet coupons will help their products edge out generic competition

If brand-name prescription medicines cost you as little as generic pills, which would you choose? A few drugmakers are betting Americans will stick with the name they know. They've begun offering U.S. patients coupons to reduce copayments on brand-name medicines and compete with new generic versions of the drugs.

22 Aug 2012

Poll finds Calif. voters strongly support federal health law; Montana lawmakers consider Medicaid expansion

States are confronting a bevy of issues in implementing the health care law including gauging public support for the law, fights over a contraception coverage mandate, expanding Medicaid and assessing the Medicare prescription drug "doughnut hole."

22 Aug 2012

Chemists develop new lab test to examine how DNA damage disrupts protein synthesis

Transcription is a cellular process by which genetic information from DNA is copied to messenger RNA for protein production. But anticancer drugs and environmental chemicals can sometimes interrupt this flow of genetic information by causing modifications in DNA.

22 Aug 2012

FDA committee to review NPS’ Gattex NDA in October

NPS Pharmaceuticals, Inc., a specialty pharmaceutical company developing therapeutics for rare gastrointestinal and endocrine disorders, today announced that the U.S. Food and Drug Administration (FDA) has notified the Company that its New Drug Application (NDA) for Gattex (teduglutide) will be discussed at the Gastrointestinal Drugs Advisory Committee meeting scheduled for October 16, 2012.

22 Aug 2012

PhaseBio commences Glymera Phase 2b study in type 2 diabetes

PhaseBio Pharmaceuticals, Inc., a privately held, clinical-stage biotechnology company developing drugs to treat diabetes, metabolic disease and cardiovascular disease, announced today that it has initiated dosing in a multicenter (USA), randomized, placebo and active comparator controlled Phase 2b study that will enroll approximately 600 patients with type 2 diabetes (hemoglobin A1c 7% - 11%) inadequately controlled with diet and exercise, metformin, a sulfonylurea or a combination of metformin/sulfonylurea.

22 Aug 2012

Study highlights Nek9 protein as decisive factor in cell division

A study by the Institute for Research in Biomedicine (IRB Barcelona) and the Center for Genomic Regulation (acronym in Catalan CRG) highlights the protein Nek9 as a decisive factor in cell division, a fundamental process for both the development of an organism and tissue maintenance.

22 Aug 2012

New silicon chips help identify patients with lupus

Researchers at the Stanford University School of Medicine and Intel Corp. have collaborated to synthesize and study a grid-like array of short pieces of a disease-associated protein on silicon chips normally used in computer microprocessors.

21 Aug 2012

First Edition: August 21, 2012

Today's headlines include reports from the campaign trail, where House candidates are turning up the Medicare debate; and from the health care marketkplace, where Aetna acquired Coventry Health, a Medicare and Medicaid insurer.

21 Aug 2012

Bile duct cancer chosen as next indication for PCI Biotech

PCI Biotech (PCIB) the Norwegian biopharmaceutical company, reported today that it has chosen bileduct cancer as the next indication for the use of its PCI (photochemical internalisation) localised cancer therapy. In this indication PCI Biotech’s proprietary photosensitiser Amphinex® will be used in combination with the generic cytotoxic agent gemcitabine. The aim is to start the clinical Proof of Concept study within end of 1H 2013.

21 Aug 2012

House Bill 6218 would create interdepartmental autoimmune disease coordinating committee

Autoimmune disease patients received a win recently when U.S. Rep. Ann Marie Buerkle (R-NY) introduced House Bill 6218 to Congress. The bill would create an interdepartmental autoimmune disease coordinating committee.

21 Aug 2012

New tool reveals surprising clues about how cancer cells respond to therapy

A new tool to observe cell behavior has revealed surprising clues about how cancer cells respond to therapy, and may offer a way to further refine personalized cancer treatments.

21 Aug 2012

MitoTarget Project and neurodegenerative diseases: an interview with Rebecca Pruss, Ph.D., CSO of Trophos

The MitoTarget Project was a project funded by the European Commission, under their FP7 programme. It was funding for a call published in 2007.

21 Aug 2012

Ipsen, Inspiration partner to commercialize IB1001 and OBI-1 for hemophilia

Inspiration Biopharmaceuticals Inc. today announced new license, development and commercialization agreements with its strategic partner, Ipsen.

21 Aug 2012

National approach can help manage drug shortages in Canada

Canada needs a national approach to managing its supply of pharmaceutical drugs, starting with a mandatory reporting system for drug shortages, argues an editorial in CMAJ (Canadian Medical Association Journal) and CPJ (Canadian Pharmacists Journal).

21 Aug 2012

Thiabendazole drug slows tumor growth and shows promise as chemotherapy for cancer

An inexpensive antifungal drug, thiabendazole, slows tumor growth and shows promise as a chemotherapy for cancer. Scientists in the College of Natural Sciences at The University of Texas at Austin made this discovery by exploiting the evolutionary relatedness of yeast, frogs, mice and humans.

21 Aug 2012

Researchers reveal possible drug targets to combat anthrax

A trawl of the genome of the deadly bacterium Bacillus anthracis has revealed a clutch of targets for new drugs to combat an epidemic of anthrax or a biological weapons attack.

21 Aug 2012

Arthritis patients prioritize lifestyle intervention research

Most patients believe that research into joint pain should focus on self-management and lifestyle modifications, suggests a UK survey of older individuals with self-reported joint pain.

20 Aug 2012

Drugs News and Research

HIV-related stigma keeps Kenyan pregnant women from having babies in health-care facilities

Chemotherapy during pregnancy: an interview with Professor Sibylle Loibl

International community must redouble efforts to ensure 'many' AIDS-free generations

Brand-name drug makers bet coupons will help their products edge out generic competition

Poll finds Calif. voters strongly support federal health law; Montana lawmakers consider Medicaid expansion

Chemists develop new lab test to examine how DNA damage disrupts protein synthesis

FDA committee to review NPS’ Gattex NDA in October

PhaseBio commences Glymera Phase 2b study in type 2 diabetes

Study highlights Nek9 protein as decisive factor in cell division

New silicon chips help identify patients with lupus

First Edition: August 21, 2012

Bile duct cancer chosen as next indication for PCI Biotech

House Bill 6218 would create interdepartmental autoimmune disease coordinating committee

New tool reveals surprising clues about how cancer cells respond to therapy

MitoTarget Project and neurodegenerative diseases: an interview with Rebecca Pruss, Ph.D., CSO of Trophos

Ipsen, Inspiration partner to commercialize IB1001 and OBI-1 for hemophilia

National approach can help manage drug shortages in Canada

Thiabendazole drug slows tumor growth and shows promise as chemotherapy for cancer

Researchers reveal possible drug targets to combat anthrax

Arthritis patients prioritize lifestyle intervention research

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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