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Enzalutamide extends castration-resistant prostate cancer survival

Enzalutamide treatment significantly improves survival in men with castration-resistant prostate cancer, demonstrate phase III trial results published in TheNew England Journal of Medicine.

20 Aug 2012

Lack of certain gene occurs in almost 28% of breast cancers

More than one out of every four cases of breast cancer is associated with a specific, missing gene - a finding that could have significant implications for chemotherapy treatments, according a recent study by Cornell University researchers.

20 Aug 2012

Anti-cancer regimens with multiple modes of action increase treatment effectiveness

Cancer may be the Harry Houdini of diseases—it often finds devious ways to escape treatment. Because cancer disables our cellular quality control mechanisms, rampant mutations that cause tumor cells to grow uncontrollably can also generate resistance to anticancer drugs. Even if 99 percent of the tumor is destroyed, that 1 percent can come roaring back. How do we knock out that 1 percent? By attacking the cancer from multiple angles, using multiple treatments and strategies.

20 Aug 2012

Paper-strip test could identify counterfeit versions of faked medicines in the world

In a thrust against the major problem of counterfeit medicines sold in developing countries, which causes thousands of illnesses and deaths annually, scientists today described development of a simple, paper-strip test that people could use to identify counterfeit versions of one of the most-frequently faked medicines in the world.

20 Aug 2012

Resveratrol might help improve mobility and prevent life-threatening falls among older people

In a stride toward better health in later life, scientists reported today that resveratrol, the so-called "miracle molecule" found in red wine, might help improve mobility and prevent life-threatening falls among older people.

20 Aug 2012

Obama, Ryan make pitches for Medicare plans

After several days in which he mentioned only generalities on the campaign trail, Representative Paul D. Ryan sought on Saturday to play offense on Medicare, attacking in detail President Obama's health care plan, seizing an issue that has the potential to be one of Mr. Ryan's biggest liabilities in joining the Republican presidential ticket.

20 Aug 2012

New evidence reveals possibility of mood-enhancing effects associated with some flavors

New evidence reveals the possibility of mood-enhancing effects associated with some flavors, stemming at least in part from natural ingredients bearing a striking chemical similarity to valproic acid, a widely used prescription mood-stabilizing drug, scientists reported here today. This effect joins those previously reported for chocolate, teas and some other known comfort foods.

20 Aug 2012

Scientists demonstrate automated worm sorter for biological research

Research into the genetic factors behind certain disease mechanisms, illness progression and response to new drugs is frequently carried out using tiny multi-cellular animals such as nematodes, fruit flies or zebra fish.

20 Aug 2012

New book on malaria tells story of Plasmodium falciparum Genome Project

Few infectious diseases can rival malaria's ability to kill and cripple. Each year the disease causes hundreds of millions of people to be sickened and more than a million - mostly African children under the age of five - die.

18 Aug 2012

Computer simulations shed light on dynamic structure of major target for anti-cancer drugs

Using advanced computer simulations, University of Utah College of Pharmacy researchers have produced moving images of a protein complex that is an important target for anti-cancer drugs.

18 Aug 2012

Safety net hospitals prepare for changes from health law; Patients hesitant to challenge doctors

Safety-net hospitals – which often provide care to low-income and uninsured populations – are facing reduced federal and state support for uncompensated care under the Affordable Care Act. However, this study points out that 23 million people will remain uninsured and continue to need care from the hospitals.

18 Aug 2012

Mylan Pharmaceuticals receives FDA approval for pioglitazone tablets to treat type 2 diabetes

The U.S. Food and Drug Administration today approved the first generic version of Actos (pioglitazone hydrochloride) tablets. Along with diet and exercise, pioglitazone is used to improve blood glucose control in adults with type 2 diabetes.

18 Aug 2012

Age, drugs, and disease alter sleep in Parkinson’s disease

Sleep patterns in patients with Parkinson’s disease are affected by age, disease severity, and dopamine agonists, German research indicates.

17 Aug 2012

Top-of-the-ticket sparring focuses on Medicare

In a Wednesday campaign appearance, President Barack Obama and GOP presidential hopeful Mitt Romney went on the attack, trading barbs over the Medicare program. For Romney, it included taking steps to distance himself from the ideas advanced in the House of Representatives by Rep. Paul Ryan, his pick for running mate.

17 Aug 2012

Two eminent cancer specialists and EORTC to be recognized at ESMO 2012 Congress

The European Society for Medical Oncology (ESMO) announced today the names of two eminent cancer specialists and one European institution that will be recognized for their contribution to the advancement of medical oncology at the ESMO 2012 Congress.

17 Aug 2012

Diabetes Research Institute to receive JDRF-HCT grant for islet encapsulation study

JDRF, in collaboration with The Leona M. and Harry B. Helmsley Charitable Trust (HCT), announced today that it has finalized a grant in the area of islet cell encapsulation to Dr. Camillo Ricordi, M.D. and a team of investigators at the Diabetes Research Institute (DRI), based at the University of Miami (FL).

17 Aug 2012

Pyruvate kinase M2 fuels tumor growth by influencing H3 histone protein

A metabolic protein that nourishes cancer cells also activates tumor-promoting genes by loosening part of the packaging that entwines DNA to make up chromosomes, a team led by scientists at The University of Texas MD Anderson Cancer Center reports in the Aug. 16 issue of Cell.

17 Aug 2012

Mepolizumab almost halves exacerbations in severe asthma patients

The largest study of patients with severe asthma to date, published in The Lancet special issue on respiratory medicine, shows that those treated with the monoclonal antibody mepolizumab experienced an almost 50% reduction in severe exacerbations, emergency room visits, and hospitalisations compared with patients given placebo.

17 Aug 2012

Study examines whether eribulin offers added benefit to women with breast cancer

Eribulin was approved in March 2011 for women with locally advanced or metastasizing breast cancer in whom the disease has progressed despite prior drug therapy.

17 Aug 2012

ACOEM integrates U.S. FDA's National Drug Code data into APG-I

The American College of Occupational and Environmental Medicine (ACOEM) has integrated the U.S. Federal Drug Administration's National Drug Code (NDC) data into APG-I, the College's on-line Occupational Medicine Practice Guidelines data base.

17 Aug 2012

Drugs News and Research

Enzalutamide extends castration-resistant prostate cancer survival

Lack of certain gene occurs in almost 28% of breast cancers

Anti-cancer regimens with multiple modes of action increase treatment effectiveness

Paper-strip test could identify counterfeit versions of faked medicines in the world

Resveratrol might help improve mobility and prevent life-threatening falls among older people

Obama, Ryan make pitches for Medicare plans

New evidence reveals possibility of mood-enhancing effects associated with some flavors

Scientists demonstrate automated worm sorter for biological research

New book on malaria tells story of Plasmodium falciparum Genome Project

Computer simulations shed light on dynamic structure of major target for anti-cancer drugs

Safety net hospitals prepare for changes from health law; Patients hesitant to challenge doctors

Mylan Pharmaceuticals receives FDA approval for pioglitazone tablets to treat type 2 diabetes

Age, drugs, and disease alter sleep in Parkinson’s disease

Top-of-the-ticket sparring focuses on Medicare

Two eminent cancer specialists and EORTC to be recognized at ESMO 2012 Congress

Diabetes Research Institute to receive JDRF-HCT grant for islet encapsulation study

Pyruvate kinase M2 fuels tumor growth by influencing H3 histone protein

Mepolizumab almost halves exacerbations in severe asthma patients

Study examines whether eribulin offers added benefit to women with breast cancer

ACOEM integrates U.S. FDA's National Drug Code data into APG-I

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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