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Scientists restore sense of smell in mice through gene therapy

Scientists have restored the sense of smell in mice through gene therapy for the first time -- a hopeful sign for people who can't smell anything from birth or lose it due to disease.

3 Sep 2012

Chronic nerve pain: an interview with Professor Sally Lawson

Chronic nerve pain results from pathological changes within a nerve that appear to be self-sustaining and thus the pain continues for a long time.

30 Aug 2012

EphA4 receptor may be promising target for future ALS drug

Leuven scientists (VIB/KU Leuven) are using zebrafish as a model in their search for genes that play a role in the mechanism of amyotrophic lateral sclerosis (ALS). As a result, they have identified a molecule that could be the target for a future ALS treatment.

28 Aug 2012

Abnormalities in mitochondrial length promote development of neurodegenerative diseases

Goldilocks was on to something when she preferred everything "just right." Harvard Medical School researchers have found that when it comes to the length of mitochondria, the power-producing organelles, applying the fairy tale's mantra is crucial to the health of a cell. More specifically, abnormalities in mitochondrial length promote the development of neurodegenerative diseases such as Alzheimer's.

24 Aug 2012

Confocal light sheet microscopy yields high-resolution views of brain’s neural pathways

Shortly after the Hubble Space Telescope went into orbit in 1990 it was discovered that the craft had blurred vision. Fortunately, Space Shuttle astronauts were able to remedy the problem a few years later with supplemental optics. Now, a team of Italian researchers has performed a similar sight-correcting feat for a microscope imaging technique designed to explore a universe seemingly as vast as Hubble's but at the opposite end of the size spectrum—the neural pathways of the brain.

24 Aug 2012

Study shows how astrocytes control new neuron generation in the brain

Researchers from the Laboratory of astrocyte biology and CNS regeneration headed by Prof. Milos Pekny just published a research article in a prestigious journal Stem Cells on the molecular mechanism that controls generation of new neurons in the brain.

24 Aug 2012

New UCLA study pinpoints unique human patterns of gene activity in the brain

Human and chimp brains look anatomically similar because both evolved from the same ancestor millions of years ago. But where does the chimp brain end and the human brain begin? A new UCLA study pinpoints uniquely human patterns of gene activity in the brain that could shed light on how we evolved differently than our closest relative.

23 Aug 2012

New imaging technique reveals the brain's continuous renovation

Using bioluminescent proteins from a jellyfish, a team of scientists has lit up the inside of a neuron, capturing spectacular video footage that shows the movement of proteins throughout the cell.

23 Aug 2012

Preemptive cognitive training can help the brain function normally later in life

Preemptive cognitive training—an early intervention to address neuropsychiatric deficiencies—can help the brain function normally later in life, a team of researchers has found through a series of experiments on laboratory rats.

23 Aug 2012

Study might help solve the biggest mystery of Parkinson’s

The recent discoveries that α-Synuclein(α-Syn) protein, a central player in Parkinson´s disease (PD) brain destruction, could not only pass from one neuron to another but also exist outside neuronal cells has led to major rethink on the disease.

23 Aug 2012

Scientists unravel how brain cells encode pronunciation of individual vowels in speech

Diagnosed with Lou Gehrig's disease at 21, British physicist Stephen Hawking, now 70, relies on a computerized device to speak. Engineers are investigating the use of brainwaves to create a new form of communication for Hawking and other people suffering from paralysis. -Daily Mail

22 Aug 2012

Investigators discover biological explanation for why low levels of oxygen advance SMA symptoms

Investigators at Nationwide Children's Hospital may have discovered a biological explanation for why low levels of oxygen advance spinal muscular atrophy (SMA) symptoms and why breathing treatments help SMA patients live longer. The findings appear in Human Molecular Genetics.

22 Aug 2012

Biomedical engineer devises new noise model that is closer to the biological reality

Biomedical engineer Muhammet Uzuntarla from Bulent Ecevit University, Turkey, and his colleagues present a biologically accurate model of the underlying noise which is present in the nervous system.

16 Aug 2012

Scientists reveal how TREX proteins act as passport for transfer of cell blueprints

Decoded process could hold the key to future treatments for a wide range of chronic health problems including Motor Neuron Disease, myotonic dystrophy and a wide range of cancers, University of Sheffield scientists have revealed.

16 Aug 2012

Schizophrenia and the immune system: an interview with Prof Cyndi Shannon Weickert

Schizophrenia is the most disabling disease impacting youth today. It impacts 1% of the total population and typically causes withdrawal from society, loss in IQ, disordered thought and speech, hallucinations and delusions.

14 Aug 2012

Chronic nerve pain: researchers identify which sensory nerve cells are responsible

New research, led by academics at the University of Bristol and published in the journal Pain, has identified the subtypes of sensory nerve cells that are likely to contribute to long-term nerve pain from partial nerve injury. It is hoped this will aid in development of more effective pain killers.

13 Aug 2012

Molecular missteps disrupt brain function in adult-onset muscular dystrophy

The molecular missteps that disrupt brain function in the most common form of adult-onset muscular dystrophy have been revealed in a new study published by Cell Press. Myotonic dystrophy is marked by progressive muscle wasting and weakness, as well as excessive daytime sleepiness, memory problems, and mental retardation.

10 Aug 2012

NSF awards Yale University and UCSD collaborative grant to develop Neuroscience Gateway

The University of California, at San Diego and Yale University have been awarded a collaborative grant by the National Science Foundation (NSF) to develop a Neuroscience Gateway (NSG) that gives neuroscientists broadened access to essential high-performance computing (HPC) and storage resources.

9 Aug 2012

Two major classes of brain cells repress neural activity in specific mathematical ways

The brain has billions of neurons, arranged in complex circuits that allow us to perceive the world, control our movements and make decisions. Deciphering those circuits is critical to understanding how the brain works and what goes wrong in neurological disorders.

9 Aug 2012

Studies in mice reveal how mood-altering drugs may affect brain stem cells

Working with mice, Johns Hopkins researchers say they have figured out how stem cells found in a part of the brain responsible for learning, memory and mood regulation decide to remain dormant or create new brain cells. Apparently, the stem cells "listen in" on the chemical communication among nearby neurons to get an idea about what is stressing the system and when they need to act.

7 Aug 2012

Neuron News and Research

Scientists restore sense of smell in mice through gene therapy

Chronic nerve pain: an interview with Professor Sally Lawson

EphA4 receptor may be promising target for future ALS drug

Abnormalities in mitochondrial length promote development of neurodegenerative diseases

Confocal light sheet microscopy yields high-resolution views of brain’s neural pathways

Study shows how astrocytes control new neuron generation in the brain

New UCLA study pinpoints unique human patterns of gene activity in the brain

New imaging technique reveals the brain's continuous renovation

Preemptive cognitive training can help the brain function normally later in life

Study might help solve the biggest mystery of Parkinson’s

Scientists unravel how brain cells encode pronunciation of individual vowels in speech

Investigators discover biological explanation for why low levels of oxygen advance SMA symptoms

Biomedical engineer devises new noise model that is closer to the biological reality

Scientists reveal how TREX proteins act as passport for transfer of cell blueprints

Schizophrenia and the immune system: an interview with Prof Cyndi Shannon Weickert

Chronic nerve pain: researchers identify which sensory nerve cells are responsible

Molecular missteps disrupt brain function in adult-onset muscular dystrophy

NSF awards Yale University and UCSD collaborative grant to develop Neuroscience Gateway

Two major classes of brain cells repress neural activity in specific mathematical ways

Studies in mice reveal how mood-altering drugs may affect brain stem cells

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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