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Global market value of Alzheimer's disease therapeutics could soar to $8 billion: GEN

The global market value of Alzheimer's disease therapeutics could soar to the $8 billion range once therapeutics are approved that actually change the course of the disease, reports Genetic Engineering & Biotechnology News (GEN).

8 Aug 2012

Statins and diabetes both increase cataract risk

Patients using cholesterol-lowering statin drugs may be at increased risk of developing age-related cataracts, according to a study - "Age-related Cataract Is Associated with Type 2 Diabetes and Statin Use", in the August issue of Optometry and Vision Science, official journal of the American Academy of Optometry.

8 Aug 2012

Clinton discusses global HIV efforts with South African officials during 11-day African tour

U.S. Secretary of State Hillary Clinton on Tuesday visited officials in South Africa and discussed the response to HIV/AIDS, the Associated Press/Huffington Post reports. Speaking with Foreign Minister Maite Nkoana-Mashabane "in the second cabinet-level strategic dialogue between the two nations," Clinton said "that global efforts to stop the virus 'have saved hundreds of thousands of lives,'" the news service writes.

8 Aug 2012

Trans-Pacific Partnership trade agreement could restrict access to affordable, life-saving drugs

In this post in the PLoS "Speaking of Medicine" blog, Judit Rius Sanjuan, a lawyer from Barcelona, Spain, and the U.S. manager of the Access Campaign at Medecins Sans Frontieres (MSF), says the Trans-Pacific Partnership (TPP), a regional trade agreement that currently involves 11 countries but is slated for further expansion across the Asia-Pacific region, is threatening the prospects for an AIDS-free generation.

8 Aug 2012

Drug research “innovation crisis” is a myth

The widely touted “innovation crisis” in pharmaceutical research is a myth, argue experts in an article published on bmj.com today.

8 Aug 2012

Study compares mortality rates among RA patients treated with individual TNF inhibitors

New research confirms no significant difference in the rates of death among patients with rheumatoid arthritis (RA) who were exposed to one of several TNF inhibitors used to treat RA, adalimumab (Humira), etanercept (Enbrel), and infliximab (Remicade).

8 Aug 2012

Certain patterns of brain activity may help predict kids at risk of heavy drinking

Heavy drinking is known to affect teenagers' developing brains, but certain patterns of brain activity may also help predict which kids are at risk of becoming problem drinkers, according to a study in the September issue of the Journal of Studies on Alcohol and Drugs.

8 Aug 2012

New class of drugs reduces adverse effects of cellular damage from cancer chemotherapy

Chemotherapy kills tumor cells, but it also wreaks havoc on the rest of the body. A team of researchers led by Igor Roninson of the South Carolina College of Pharmacy just reported the discovery of a new class of drugs that reduces the adverse effects of cellular damage from chemotherapy.

8 Aug 2012

Older men with higher levels of free testosterone more likely to develop prostate cancer

New research finds older men with higher levels of free testosterone have an increased risk of prostate cancer. Australian researchers spent a decade exploring the testosterone-prostate cancer connection by comparing natural testosterone levels of men in their 70s and 80s, those with prostate cancer and without.

8 Aug 2012

Orexigen Therapeutics reports net loss of $16.7 million for second quarter 2012

Orexigen Therapeutics, Inc., a biopharmaceutical company focused on the treatment of obesity, today announced financial results for the second quarter of 2012.

7 Aug 2012

Advances in HIV/AIDS therapy and the International AIDS Conference: an interview with Professor Sharon Lewin

The anti-HIV drugs, also known as anti-retroviral therapy, came about in the mid ‘90’s. These involved using at least 3 different drugs together.

7 Aug 2012

Geisel professor concerned about steroid abuse by adolescents

Leslie Henderson is concerned about steroid abuse, not necessarily by sports luminaries like Barry Bonds and Mark McGwire, but rather by adolescents.

7 Aug 2012

Clinical trial targets breast cancer cells by injecting trastuzumab directly into the spinal fluid

In two to five percent of women with breast cancer, tumor cells migrate into the spinal fluid invading the tissue surrounding the brain and spinal cord called the meninges. While a rare complication, the condition is challenging because there is no agreed-upon standard of treatment, leaving little hope for patients affected. Northwestern Medicine- researchers are currently examining a novel approach to delivering an FDA approved drug that they hope will advance research for this type of cancer and lead to discoveries that may improve outcomes in the future.

7 Aug 2012

Blood levels of IL-6 protein may also serve as red flag for relapse in schizophrenia patients

Blood levels of a protein that helps regulate inflammation may also serve as a red flag for relapse in some schizophrenia patients, researchers said.

7 Aug 2012

Researchers identify myostatin as potential therapeutic target for muscular disorders

The study of muscular system protein myostatin has been of great interest to researchers as a potential therapeutic target for people with muscular disorders. Although much is known about how myostatin affects muscle growth, there has been disagreement about what types of muscle cells it acts upon. New research from a team including Carnegie's Chen-Ming Fan and Christoph Lepper narrows down the field to one likely type of cell.

7 Aug 2012

Novartis’ pasireotide offers symptom relief for patients with advanced neuroendocrine tumors

A researcher at Moffitt Cancer Center and his international team of colleagues have reported study results on a novel multireceptor-targeted somatostatin analogue called pasireotide (SOM230) manufactured by Novartis Pharma AG.

7 Aug 2012

Scripps Florida scientists to identify and develop new therapeutic approaches against cancers

Scientists from the Florida campus of The Scripps Research Institute have been awarded approximately $1.5 million from the National Institutes of Health to identify and develop new therapeutic approaches against a broad spectrum of cancers.

7 Aug 2012

Studies in mice reveal how mood-altering drugs may affect brain stem cells

Working with mice, Johns Hopkins researchers say they have figured out how stem cells found in a part of the brain responsible for learning, memory and mood regulation decide to remain dormant or create new brain cells. Apparently, the stem cells "listen in" on the chemical communication among nearby neurons to get an idea about what is stressing the system and when they need to act.

7 Aug 2012

Exercise hope for drug-resistant hypertension

Even patients who have hypertension despite taking multiple antihypertensive drugs can achieve blood pressure reductions with a program of aerobic exercise, research shows.

6 Aug 2012

Cardiovascular risk present across chronic rheumatic diseases

Patients across the spectrum of rheumatic diseases, not just those with rheumatoid arthritis, have a significantly increased prevalence of cardiovascular risk factors compared with the general population, the results of a Dutch study indicate.

6 Aug 2012

Drugs News and Research

Global market value of Alzheimer's disease therapeutics could soar to $8 billion: GEN

Statins and diabetes both increase cataract risk

Clinton discusses global HIV efforts with South African officials during 11-day African tour

Trans-Pacific Partnership trade agreement could restrict access to affordable, life-saving drugs

Drug research “innovation crisis” is a myth

Study compares mortality rates among RA patients treated with individual TNF inhibitors

Certain patterns of brain activity may help predict kids at risk of heavy drinking

New class of drugs reduces adverse effects of cellular damage from cancer chemotherapy

Older men with higher levels of free testosterone more likely to develop prostate cancer

Orexigen Therapeutics reports net loss of $16.7 million for second quarter 2012

Advances in HIV/AIDS therapy and the International AIDS Conference: an interview with Professor Sharon Lewin

Geisel professor concerned about steroid abuse by adolescents

Clinical trial targets breast cancer cells by injecting trastuzumab directly into the spinal fluid

Blood levels of IL-6 protein may also serve as red flag for relapse in schizophrenia patients

Researchers identify myostatin as potential therapeutic target for muscular disorders

Novartis’ pasireotide offers symptom relief for patients with advanced neuroendocrine tumors

Scripps Florida scientists to identify and develop new therapeutic approaches against cancers

Studies in mice reveal how mood-altering drugs may affect brain stem cells

Exercise hope for drug-resistant hypertension

Cardiovascular risk present across chronic rheumatic diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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