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Novel approaches to fight infections presented at the Pipeline Corner at ECCMID

The European Society of Clinical Microbiology and Infectious Diseases (ESCMID) announced breaking developments in the global fight against infections – with new mechanisms and approaches presented by smaller companies in a dedicated pipeline session at the annual congress (ECCMID) in Copenhagen.

30 Apr 2015

Luminex provides clinical trial update on ARIES HSV 1&2 Assay

Luminex Corporation today announced that testing at the clinical trial sites for the ARIES HSV 1&2 Assay is now complete. The next steps, including site to site reproducibility testing, followed by data analysis and assembly of the data package for submission to the FDA, are now underway.

From Luminex 28 Apr 2015

Preclinical data from Synthetic Biologics' SYN-005 for Pertussis treatment presented at ECCMID 2015

Synthetic Biologics, Inc., a developer of pathogen-specific therapies for serious infections and diseases, with a focus on protecting the microbiome, announced that preclinical data from its novel SYN-005 program for the treatment of Pertussis were presented in two posters at ECCMID 2015 (European Congress of Clinical Microbiology and Infectious Diseases), on April 25, 2015, in Copenhagen, Denmark.

27 Apr 2015

Common tapeworm drug effectively treats MRSA superbugs in lab

A new study provides evidence from lab experiments that a drug already used in people to fight tapeworms might also prove effective against strains of the superbug MRSA, which kills thousands of people a year in the United States.

24 Apr 2015

New patent-pending detection method identifies bacteria contaminating oysters

In a major breakthrough in shellfish management and disease prevention, researchers at the University of New Hampshire have discovered a new method to detect a bacterium that has contaminated New England oyster beds and sickened consumers who ate the contaminated shellfish.

23 Apr 2015

Winners of GSA poster awards announced at Fungal Genetics Conference

The Genetics Society of America and the community of fungal geneticists are pleased to announce the winners of the GSA poster awards at the 28th Fungal Genetics Conference, which took place in Pacific Grove, CA, March 17-22, 2015.

22 Apr 2015

New mathematical model to predict pharmacodynamic activity may help improve drug discovery

A new mathematical model that uses drug-target kinetics to predict how drugs work in vivo may provide a foundation to improve drug discovery, which is frequently hampered by the inability to predict effective doses of drugs.

21 Apr 2015

More personalized treatment protocols can reduce mortality in cancer patients with severe pneumonia

Cancer patients are more likely to get infections. Pneumonia is the most frequent type of infection in this group and a frequent cause of ICU admission and mortality. A study conducted by researchers from the D'Or Institute for Research and Education in partnership with Brazilian hospitals and universities analyzed the factors associated with severe pneumonia in hospitalized cancer patients and suggests that more personalized treatment protocols can reduce mortality in these patients.

13 Apr 2015

Infectious diseases experts release new guidance to avoid infections during hospital visits

Leading infectious diseases experts have released new guidance for healthcare facilities looking to establish precautions for visitors of patients with infectious diseases. The guidance looks to reduce the potential for healthcare visitors in spreading dangerous bacteria within the healthcare facility and community.

13 Apr 2015

New automated tool rapidly delivers large particles into mammalian cells

A new device developed by UCLA engineers and doctors eventually help scientists study the development of disease, enable them to capture improved images of the inside of cells and lead to other improvements in medical and biological research.

10 Apr 2015

NIAID funds nine research projects to advance rapid diagnostics tests for drug-resistant bacteria

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded more than $11 million in first-year funding for nine research projects supporting enhanced diagnostics to rapidly detect antimicrobial-resistant bacteria.

10 Apr 2015

Researchers identify phenomenon that explains effects of oxidative stress on immune cells

You're up in the mountains, the snow is blindingly white, and the sun is blazing down from the sky: ideal skiing conditions - but any skiers carrying the herpes virus might also have to reckon with the onset of cold sores after their day out.

10 Apr 2015

Seal Shield's new Airocide DS air purifier may help eliminate 'Super Bugs' in hospitals

Seal Shield LLC (Jacksonville, FL), today announced the new Airocide DS air purifier. The Airocide DS is a table top or bed side air purification product that uses a unique photocatalytic biocide reactor to eliminate viral, fungal and bacterial pathogens from the air. Developed by NASA, Airocide converts dangerous bacteria, virus and destructive VOC's into harmless water vapor without producing ozone or other harmful byproducts.

9 Apr 2015

Study may point to immediate cause of CF exacerbations

In the genetic disorder cystic fibrosis (CF), the most severe symptoms are recurring episodes of lung inflammation and bacterial infection (known as "exacerbations") that happen from one to three times a year and cause ever-increasing amounts of lung damage through the course of a CF patient's life.

9 Apr 2015

New approach could help identify novel drug targets to combat lethal fungal infections

By modifying the CRISPR-Cas genome editing system, Whitehead Institute researchers are now able to manipulate Candida albicans' genome systematically--an approach that could help identify novel targets for therapies against this serious pathogen for which there are a limited number of anti-fungal agents.

6 Apr 2015

Dartmouth researchers use new strategies to target drug-resistant pathogens

By engineering antibacterial enzymes, Dartmouth investigators led by Karl Griswold, PhD are using novel strategies to target the prevalent drug-resistant bacterium Staphylococcus aureus.

3 Apr 2015

Study examines efficacy of continuous UV-C robots versus pulsed xenon in preventing infection

The efficacy of continuous UV-C disinfection robots versus pulsed xenon (PU-UX) was highlighted in a recently published study of ultraviolet (UV) light disinfection systems by an influential infection prevention research team, including Curtis Donskey, M.D.

1 Apr 2015

New research reveals how a deadly fungus grows and kills immune cells

New research from the University of Toronto has scientists re-thinking how a lethal fungus grows and kills immune cells. The study hints at a new approach to therapy for Candida albicans, one of the most common causes of bloodstream infections.

31 Mar 2015

New approach allows researchers to trap and watch highly motile cells

Optical imaging of highly motile cells or cells in suspension, such as bacterial systems, yeast cells, and immune cells, is a challenging task, in many cases it is just not possible. The human immunodeficiency virus (HIV), for example, can spread very efficiently from an infected T cell to an uninfected T cell through direct cell-cell contact.

31 Mar 2015

Synthetic Biologics begins SYN-004 Phase 2a clinical trial to prevent C. difficile infection

Synthetic Biologics, Inc., a developer of pathogen-specific therapies for serious infections and diseases, with a focus on protecting the microbiome, today announced the initiation of a Phase 2a clinical trial to evaluate the gastrointestinal (GI) antibiotic-degrading effects and the safety of SYN-004, the Company's investigational oral beta-lactamase enzyme designed to protect the microbiome and prevent C. difficile infection (CDI).

30 Mar 2015

Pathogen News and Research

Novel approaches to fight infections presented at the Pipeline Corner at ECCMID

Luminex provides clinical trial update on ARIES HSV 1&2 Assay

Preclinical data from Synthetic Biologics' SYN-005 for Pertussis treatment presented at ECCMID 2015

Common tapeworm drug effectively treats MRSA superbugs in lab

New patent-pending detection method identifies bacteria contaminating oysters

Winners of GSA poster awards announced at Fungal Genetics Conference

New mathematical model to predict pharmacodynamic activity may help improve drug discovery

More personalized treatment protocols can reduce mortality in cancer patients with severe pneumonia

Infectious diseases experts release new guidance to avoid infections during hospital visits

New automated tool rapidly delivers large particles into mammalian cells

NIAID funds nine research projects to advance rapid diagnostics tests for drug-resistant bacteria

Researchers identify phenomenon that explains effects of oxidative stress on immune cells

Seal Shield's new Airocide DS air purifier may help eliminate 'Super Bugs' in hospitals

Study may point to immediate cause of CF exacerbations

New approach could help identify novel drug targets to combat lethal fungal infections

Dartmouth researchers use new strategies to target drug-resistant pathogens

Study examines efficacy of continuous UV-C robots versus pulsed xenon in preventing infection

New research reveals how a deadly fungus grows and kills immune cells

New approach allows researchers to trap and watch highly motile cells

Synthetic Biologics begins SYN-004 Phase 2a clinical trial to prevent C. difficile infection

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Why use light scattering to analyze proteins and viral vectors?

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