Therapy News and Research

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Combination of carboplatin, paclitaxel and RT3D shows promise against head and neck cancer

A naturally-occurring harmless human virus may be able to boost the effects of two standard chemotherapy drugs in some cancer patients, according to early stage trial data published in Clinical Cancer Research.

4 Apr 2012

Combination of gemcitabine and TH-302 improves survival in advanced pancreatic cancer

The combination of the novel drug TH-302 with the standard drug gemcitabine has shown early signs of delaying the worsening of cancer in patients with advanced pancreatic cancer, a Mayo Clinic-led study has found.

4 Apr 2012

Johns Hopkins devises new seizure detection software

Epilepsy affects 50 million people worldwide, but in a third of these cases, medication cannot keep seizures from occurring. One solution is to shoot a short pulse of electricity to the brain to stamp out the seizure just as it begins to erupt. But brain implants designed to do this have run into a stubborn problem: too many false alarms, triggering unneeded treatment. To solve this, Johns Hopkins biomedical engineers have devised new seizure detection software that, in early testing, significantly cuts the number of unneeded pulses of current that an epilepsy patient would receive.

4 Apr 2012

Lilly announces results of three preclinical studies that focus on c-MET receptor

Eli Lilly and Company today announced results of three preclinical studies focused on c-MET, a receptor tyrosine kinase that, when it functions normally, plays a key role in transmitting signals within a cell.

3 Apr 2012

Early appendectomy can reduce length of stay, medical interventions and hospital charges

Pediatric surgeons can lower health care costs if they remove a young patient's perforated appendix sooner rather than later, according to new study results published in the April issue of the Journal of the American College of Surgeons.

3 Apr 2012

Doctors more reluctant to start their patients on insulin

Doctors are more reluctant to start their patients on insulin than the patients are themselves, according to a new study led by researchers at St. Michael's Hospital.

3 Apr 2012

Prenatal antipsychotic drug exposure may reduce scores on infant neuromotor screening

Among 6-month-old infants, a history of intrauterine antipsychotic medication exposure was associated with significantly lower scores on a standard test of neuromotor performance, according to a report published Online First by Archives of General Psychiatry, a JAMA Network publication.

3 Apr 2012

Funding shortfalls could hinder implementation of treatment as prevention strategies, Al Jazeera reports

Al Jazeera examines the administration of combination antiretroviral therapy (ART) worldwide, focusing on treatment as prevention (TasP), but says current funding levels are insufficient to implement the strategy.

3 Apr 2012

New data demonstrates anti-cancer activities of Oncoprex

New data demonstrating the anti-cancer activities of Oncoprex were presented at the 2012 Annual Meeting of the American Association for Cancer Research (AACR) in Chicago, IL. The study, "Synergistic antitumor activity of AKT inhibitor MK2206 and FUS1 nanoparticles in LKB1 mutant NSCLC" (Meng J, Lara-Guerra H, Ji L, Roth JA) is authored by a team of investigators from The University of Texas MD Anderson Cancer Center.

3 Apr 2012

PET allows survival predictions in sarcoma after initial cycle of neoadjuvant chemo

An early Positron Emission Tomography (PET) response after the initial cycle of neoadjuvant chemotherapy can be used to predict increased survival in patients with soft tissue sarcomas, according to a study by researchers with UCLA's Jonsson Comprehensive Cancer Center.

3 Apr 2012

MMRF announces unique oncology research partnership

The Multiple Myeloma Research Foundation (MMRF) today announced a unique oncology research partnership. This multi-year agreement involves several partners including the Translational Genomics Research Institute (TGen), Spectrum Health, and the Van Andel Research Institute.

3 Apr 2012

New research: ADHD is more than one disorder

According to new research conducted at Oregon Health & Science University, Attention Deficit Hyperactivity Disorder (ADHD) is more than one disorder. It's an entire family of disorders, much like the multiple subtypes of cancer.

3 Apr 2012

Merck announces data from ZOSTAVAX Phase III study on shingles

Merck, known as MSD outside the United States and Canada, announced today that data from the pivotal Phase III study with ZOSTAVAX(Zoster Vaccine Live) in adults ages 50 to 59 were published in the April 1 issue of Clinical Infectious Diseases.

3 Apr 2012

Some autistic children may “bloom” socially with early and the right therapy

According to the latest figures from the U.S. Centers for Disease Control and Prevention 1 in 88 U.S. children have autism, a spectrum of disorders that ranges from severe communication and intellectual disability to much milder symptoms seen in children with Asperger's syndrome. Autism is marked by a group of symptoms, all arising from atypical brain development that causes problems with socialization, communication and behavior. Although the disorder can be mild or severe, in general children with autism have trouble communicating and making friends.

2 Apr 2012

Non-invasive brain stimulation cuts time to improve speech in stroke patients

One of the most frustrating challenges for some stroke patients can be the inability to find and speak words even if they know what they want to say. Speech therapy is laborious and can take months. New research is seeking to cut that time significantly, with the help of non-invasive brain stimulation.

2 Apr 2012

PolyTherics, Spirogen enter research collaboration to produce novel ADCs for treatment of cancer

PolyTherics Limited, a provider of solutions to enable the development of better biopharmaceuticals, and Spirogen Limited, a leading oncology-focused company developing DNA sequence-targeted agents, announce that they have formed a research collaboration to develop antibody drug conjugates that combine PolyTherics' proprietary site-specific conjugation chemistry with Spirogen's highly potent novel cytotoxic drugs to produce novel ADCs for the treatment of cancer.

2 Apr 2012

Eisai, University of Kansas grant water-soluble pro-drug technology patent to OneWorld Health

OneWorld Health (OWH), a nonprofit that develops lifesaving medicines for neglected diseases, announced that it has signed a nonexclusive patent agreement with Eisai Co., Ltd., for a water-soluble pro-drug technology patent. OWH will use the pro-drug technology to advance development of iOWH032, its new drug to treat acute secretory diarrhea.

2 Apr 2012

TYRX enrolls 1000th patient in CITADEL/CENTURION AIGISRx Antibacterial Envelope studies

TYRX, Inc., the leader in the commercialization of implantable medical devices designed to help reduce surgical-site infections (SSIs) associated with cardiovascular implantable electronic devices (CIEDs), announced today that the 1000th patient has been enrolled into the CITADEL & CENTURION clinical studies evaluating the company's AIGISRx Antibacterial Envelope.

2 Apr 2012

New diagnostic test for Trichomonas vaginalis

Medical Diagnostic Laboratories, L.L.C. is a CLIA certified infectious disease laboratory which specializes in high-complexity, state-of-the-art, automated DNA-based molecular analyses.

2 Apr 2012

AlloCure closes $25 million Series B venture financing

AlloCure, Inc., a clinical stage biotechnology company focused on the treatment of kidney disease, today announced the closing of a $25 million Series B venture financing.

2 Apr 2012

Therapy News and Research

Combination of carboplatin, paclitaxel and RT3D shows promise against head and neck cancer

Combination of gemcitabine and TH-302 improves survival in advanced pancreatic cancer

Johns Hopkins devises new seizure detection software

Lilly announces results of three preclinical studies that focus on c-MET receptor

Early appendectomy can reduce length of stay, medical interventions and hospital charges

Doctors more reluctant to start their patients on insulin

Prenatal antipsychotic drug exposure may reduce scores on infant neuromotor screening

Funding shortfalls could hinder implementation of treatment as prevention strategies, Al Jazeera reports

New data demonstrates anti-cancer activities of Oncoprex

PET allows survival predictions in sarcoma after initial cycle of neoadjuvant chemo

MMRF announces unique oncology research partnership

New research: ADHD is more than one disorder

Merck announces data from ZOSTAVAX Phase III study on shingles

Some autistic children may “bloom” socially with early and the right therapy

Non-invasive brain stimulation cuts time to improve speech in stroke patients

PolyTherics, Spirogen enter research collaboration to produce novel ADCs for treatment of cancer

Eisai, University of Kansas grant water-soluble pro-drug technology patent to OneWorld Health

TYRX enrolls 1000th patient in CITADEL/CENTURION AIGISRx Antibacterial Envelope studies

New diagnostic test for Trichomonas vaginalis

AlloCure closes $25 million Series B venture financing

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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