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HIV in MSM increasing in countries of all incomes

A new Lancet Series published to coincide with the AIDS2012 meeting highlights a population where the HIV epidemic is growing in countries of all incomes: men who have sex with men (MSM). The first paper in the Series charts the epidemiology of HIV among MSM, and is by Professor Chris Beyrer, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA, and colleagues.

20 Jul 2012

Scientists develop simple assay to diagnose 'superparasites'

Belgian scientists of the Institute of Tropical Medicine (ITM) in Antwerp, Belgium made a breakthrough in bridging high tech molecular biology research on microbial pathogens and the needs of the poorest of the poor. After sequencing the complete genome of Leishmania donovani (a parasite causing one of the most important tropical diseases after malaria) in hundreds of clinical isolates, they identified a series of mutations specific of 'superparasites' and developed a simple assay that should allow tracking them anywhere.

20 Jul 2012

Short-term infection with intestinal worms may provide long-term protection against TID

Short-term infection with intestinal worms may provide long-term protection against type I diabetes (TID), suggests a study conducted by William Gause, PhD, and colleagues at the University of Medicine and Dentistry of New Jersey-New Jersey Medical School.

20 Jul 2012

ARV drug resistance levels steady in low-, middle-income countries, WHO report says

More widespread use of antiretroviral drugs (ARVs) to treat HIV infection has led to drug resistance in low- and middle-income countries, but the level "is not steep enough to cause alarm, said a survey released by the World Health Organization on Wednesday," Agence France-Presse reports.

20 Jul 2012

Community-based resources in rural Uganda can successfully provide HIV treatments

New research from the University of Alberta's School of Public Health has demonstrated that community-based resources in rural Uganda can successfully provide HIV treatments to patients, where economic and geographical barriers would typically prevent access to care.

20 Jul 2012

Study demonstrates how nerve stimulation paired with specific experiences can reorganize the brain

UT Dallas researchers recently demonstrated how nerve stimulation paired with specific experiences, such as movements or sounds, can reorganize the brain. This technology could lead to new treatments for stroke, tinnitus, autism and other disorders.

20 Jul 2012

Researchers identify six genes with driving mutations in melanoma

It's been a burning question in melanoma research: Tumor cells are full of ultraviolet (UV)-induced genetic damage caused by sunlight exposure, but which mutations drive this cancer? None have been conclusively tied to melanoma. The sheer abundance of these passenger mutations has obscured the search for genetic driver mutations that actually matter in melanoma development and progression.

20 Jul 2012

Scientists identify inhibitors of key enzyme involved in survival of malaria parasite

An international team of scientists, led by researchers from the Department of Pediatrics at the University of California, San Diego School of Medicine, have identified the first reported inhibitors of a key enzyme involved in survival of the parasite responsible for malaria. Their findings, which may provide the basis for anti-malarial drug development, are currently published in the online version of the Journal of Medicinal Chemistry.

20 Jul 2012

Scientists to create new drugs with bone formation stimulating activities

A Simon Fraser University researcher is leading a team of scientists working to create new drugs to stimulate bone regeneration - research that will be furthered by a $2.5 million grant from the Canadian Institutes of Health Research (CIHR).

20 Jul 2012

Apothecary, Verde introduce Medsaway medication disposal system

Apothecary Products, Inc., in conjunction with Verde Environmental Technologies, introduces Medsaway medication disposal system. This unique item allows you to get rid of old and unwanted drugs including narcotics, liquid medication, transdermal patches and controlled substances.

20 Jul 2012

Epithilone D effective in preventing Alzheimer's in animal models

While clinical trial results are being released regarding drugs intended to decrease amyloid production - thought to contribute to decline in Alzheimer's disease - clinical trials of drugs targeting other disease proteins, such as tau, are in their initial phases.

20 Jul 2012

Viewpoints: Researchers see potential to control HIV pandemic; The 'ceaseless attacks' on women's reproductive health

We are at a moment of extraordinary optimism in the response to the human immunodeficiency virus (HIV). A series of scientific breakthroughs ... have the potential to markedly expand the available preventive tools. There is evidence of the first cure of an HIV-infected person. And most important, the finding that early initiation of antiretroviral therapy can both improve individual patient outcomes and reduce the risk of HIV transmission to sexual partners by 96% has led many to assert what had so long seemed impossible: that control of the HIV pandemic may be achievable.

20 Jul 2012

Longer looks: Physicians and assisted suicide; Avoid getting sick in July

Peggy Sutherland was ready to die. The morphine oozing from a pump in her spine was no match for the pain of lung cancer, which had evaded treatment and invaded her ribs. … Sutherland, 68, decided to use Oregon's "Death With Dignity Act," which allows terminally-ill residents to end their lives after a 15-day requisite waiting period by self-administering a lethal prescription drug. ... But not all doctors are on board with the law.

20 Jul 2012

HAS-BLED: Atrial fibrillation patients undergoing angioplasty can still take anticoagulants

Researchers say that oral anticoagulation could improve the prognosis of atrial fibrillation patients who undergo percutaneous coronary intervention, even if they have a high bleeding risk according to the HAS-BLED score.

19 Jul 2012

Proton pump inhibitors for clopidogrel patients ‘not so dangerous’

The interaction between proton pump inhibitors and clopidogrel is “clinically unimportant,” say researchers in the BMJ.

19 Jul 2012

New AAN guideline recommends several treatments for people with Huntington's chorea

A new guideline released by the American Academy of Neurology recommends several treatments for people with Huntington's disease who experience chorea—jerky, random, uncontrollable movements that can make everyday activities challenging.

19 Jul 2012

Researchers discover potential drug targets that might reduce ventilator-induced lung inflammation

When hospital patients need assistance breathing and are placed on a mechanical ventilator for days at a time, their lungs react to the pressure generated by the ventilator with an out-of-control immune response that can lead to excessive inflammation, new research suggests.

19 Jul 2012

UNMC's ART injectables can successfully treat HIV infection

This has been a good week for breakthroughs in HIV/AIDS. Earlier this week, the Food and Drug Administration approved a daily pill, Truvada, which reduces the risk of HIV infection. Today, a University of Nebraska Medical Center research team's progress toward developing weekly or twice-monthly injectable antiretroviral therapy (ART) nanomedicines for patients with human immunodeficiency virus (HIV) infection will be highlighted as the cover story in the Journal of Infectious Diseases.

19 Jul 2012

Bryologs more potent than prostratin in treating HIV

Thanks to antiretrovirals, an AIDS diagnosis hasn't been a death sentence for nearly two decades. But highly active antiretroviral therapy, or HAART, is also not a cure.

19 Jul 2012

Huddersfield scientist receives Pain Relief Foundation grant for research into BH4 pathway

SOME victims of serious illness experience much less pain than other sufferers, thanks to a natural biochemical variation in the cells of their bodies. Now a scientist at the University of Huddersfield has been awarded research funding that will aid his project to learn more about this variation and therefore develop treatments that could lead to the relief of pain for all patients, with much less dependence on drugs that can have distressing side effects.

19 Jul 2012

Drugs News and Research

HIV in MSM increasing in countries of all incomes

Scientists develop simple assay to diagnose 'superparasites'

Short-term infection with intestinal worms may provide long-term protection against TID

ARV drug resistance levels steady in low-, middle-income countries, WHO report says

Community-based resources in rural Uganda can successfully provide HIV treatments

Study demonstrates how nerve stimulation paired with specific experiences can reorganize the brain

Researchers identify six genes with driving mutations in melanoma

Scientists identify inhibitors of key enzyme involved in survival of malaria parasite

Scientists to create new drugs with bone formation stimulating activities

Apothecary, Verde introduce Medsaway medication disposal system

Epithilone D effective in preventing Alzheimer's in animal models

Viewpoints: Researchers see potential to control HIV pandemic; The 'ceaseless attacks' on women's reproductive health

Longer looks: Physicians and assisted suicide; Avoid getting sick in July

HAS-BLED: Atrial fibrillation patients undergoing angioplasty can still take anticoagulants

Proton pump inhibitors for clopidogrel patients ‘not so dangerous’

New AAN guideline recommends several treatments for people with Huntington's chorea

Researchers discover potential drug targets that might reduce ventilator-induced lung inflammation

UNMC's ART injectables can successfully treat HIV infection

Bryologs more potent than prostratin in treating HIV

Huddersfield scientist receives Pain Relief Foundation grant for research into BH4 pathway

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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