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Stepped up measures to tack rising painkiller abuse

Prescription drug abuse is one of the largest problems in the country say experts and according to White House drug Czar Gil Kerlikowske, the Congress must require special training for doctors and other health care workers before they are allowed to prescribe powerful drugs such as OxyContin.

20 Apr 2011

Anavex: First-in-human dosing cmmenced in ANAVEX 2-73 clinical trial for Alzheimer’s

Anavex Life Sciences Corp. (“Anavex”) (OTCBB: AVXL) today announced that the first healthy human volunteers have been initially dosed in its Phase I clinical trial to evaluate ANAVEX 2-73, the company’s lead compound for Alzheimer’s disease. “We are pleased that the first volunteers have been dosed with the study drug, according to the study protocol, and no adverse events have been recorded post dosing to date," said Dr. Ozkan Yalkinoglou, Medical Director of ABX-CRO.

20 Apr 2011

ARIAD executes three exclusive out-license agreements for ARGENT cell-signaling regulation technology

ARIAD Pharmaceuticals, Inc. today announced execution of three exclusive out-license agreements for separate aspects of its ARGENT™ cell-signaling regulation technology.

20 Apr 2011

First Edition: April 20, 2011

Today's headlines include reports about new poll results showing that Americans oppose cuts to Medicare as a means to deal with the debt problem.

20 Apr 2011

Blocking abnormal movement of mutated human FUS gene also blocks ALS process

In the first animal model of Amyotrophic Lateral Sclerosis (ALS), developed by Dr. Udai Pandey, Assistant Professor of Genetics at LSU Health Sciences Center New Orleans, Dr. Pandey's lab has found in fruit flies that blocking the abnormal movement of a protein made by a mutated gene called FUS also blocks the disease process.

20 Apr 2011

Researchers discover new way to force cancer cells to self-destruct

Researchers at The Wistar Institute have found a new way to force cancer cells to self-destruct. Low doses of one anti-cancer drug currently in development, called Gamitrinib, sensitize tumor cells to a second drug, called TRAIL, also currently in clinical development as part of an anticancer regimen.

20 Apr 2011

New method allows single microchip to screen tens of thousands of genes simultaneously

RNA interference technology, which is used in cell biology, has revolutionised functional research of the gene products in the last ten years. VTT Technical Research Centre of Finland has developed a method which allows a single microchip to be used to screen the functions of tens of thousands of genes simultaneously by means of RNA interference.

20 Apr 2011

Sialix announces blood test results for early detection and treatment of breast cancer

Sialix, Inc. a pioneer in glycobiology, today announced the results of a study it participated in with researchers at the University of California, San Diego School of Medicine that could have significant impact in the prediction, early detection and treatment of cancer in humans.

20 Apr 2011

Spanish tool measures infant pain rapidly and simply

It turns out to be difficult to find out exactly how much a child who cannot yet speak suffers after a surgical operation. Researchers at the University Hospital of La Paz, in Madrid, have validated the 'Llanto' scale, the first, and only, tool in Spanish which measures infant pain rapidly and simply.

20 Apr 2011

North American legal injection drug site helps decrease overdose deaths, study shows

North America's only authorized facility for injecting illegal drugs has helped cut drug overdose deaths significantly in the Vancouver community where it is located and "should be used as a model in other cities," according to a study published on Monday in the Lancet, Reuters reports (Dowd, 4/18).

20 Apr 2011

Researchers to wind down HIV prevention trial in women after interim results find drug not offering protection from HIV

Researchers on Monday announced they were calling off a trial to test whether taking an oral HIV drug reduces the risk of HIV infection in women after interim analysis of the study showed women taking the medication were no less likely to become infected with HIV than those who were not taking the medicine, the Associated Press reports.

20 Apr 2011

Swinburne University of Technology acquires Elekta's Neuromag TRIUX MEG system

Certain brain processes happen in the blink of an eye – and even faster – which has made pinpointing these events virtually impossible. The advent of magnetoencephalography (MEG) changed all that, enabling researchers to capture brain electrical activity measured in milliseconds, and offering the potential to reveal the nature of innumerable brain disorders and diseases.

From Elekta 20 Apr 2011

Diagnostic test Xpert MTB/RIF proven fast and effective in low-resource settings

The Lancet published a significant development for TB diagnostics yesterday with concrete and encouraging study outcomes on the effectiveness of the new Xpert MTB/RIF test for TB and rifampicin resistance in realistic health care field conditions. One of the authors, Prof. Mark Nicol of the University of Cape Town (South Africa) who contributed to this study, is an EDCTP Senior Fellow. The article demonstrates that the test can effectively be used in low-resource settings to simplify early and accurate diagnosis of patients. The potential impact is a reduction in the morbidity associated with diagnostic delay, dropout and mistreatment. The article has appeared online on 19 April 2011 and will be published in volume 377 on 30 April 2011.

20 Apr 2011

Scientists detect several biomarkers to screen active drugs for Batten disease

Goethe University and Harvard Medical School start screening for active ingredients for the treatment of Batten disease

20 Apr 2011

Covidien supports FDA’s REMS for important class of pain medications

Covidien (NYSE: COV), a leading global provider of healthcare products, supports the U.S. Food and Drug Administration's Risk Evaluation and Mitigation Strategy (REMS) for an important class of pain medications.

20 Apr 2011

Diabetes in Control publishes complete list of drugs that affect blood glucose

Any clinician knows that there's a massive amount of new diabetes research and clinical information released daily, which makes keeping pace with best practices almost a full-time job.

20 Apr 2011

Researchers deploy new tool in study of tubulin tyrosine ligase in tumor growth

Many of the newest weapons in the war on cancer come in the form of personalized therapies that can target specific changes in an individual's tumor. By disrupting molecular processes in tumor cells, these drugs can keep the tumor from growing and spreading. At the forefront of this work are Binghamton University researchers, Susan Bane, and Susannah Gal, who are deploying a new tool in their study of an enzyme called tubulin tyrosine ligase, or TTL.

20 Apr 2011

Chronic inflammation due to infection may lead to cancer

A new study shows how inflammation can help cause cancer. Chronic inflammation due to infection or to conditions such as chronic inflammatory bowel disease is associated with up to 25 percent of all cancers.

20 Apr 2011

Diabetes in Control announces clinical slide presentation library for medical community

Diabetes in Control (http://www.diabetesincontrol.com), an e-newsletter dedicated to keeping clinicians current with the rapid changes in diabetes care, expands its quest to provide them with the best tools for their practice.

20 Apr 2011

MSF calls on African governments, WHO to switch to newer, more expensive treatment for severe malaria

Nearly 200,000 deaths from severe malaria could be averted if African governments replaced the low-cost antimalarial quinine with the more expensive but more effective drug artesunate, according to a report (.pdf) released Tuesday by Medicins Sans Frontieres (MSF), Reuters reports (Kelland, 4/19).

20 Apr 2011

Drugs News and Research

Stepped up measures to tack rising painkiller abuse

Anavex: First-in-human dosing cmmenced in ANAVEX 2-73 clinical trial for Alzheimer’s

ARIAD executes three exclusive out-license agreements for ARGENT cell-signaling regulation technology

First Edition: April 20, 2011

Blocking abnormal movement of mutated human FUS gene also blocks ALS process

Researchers discover new way to force cancer cells to self-destruct

New method allows single microchip to screen tens of thousands of genes simultaneously

Sialix announces blood test results for early detection and treatment of breast cancer

Spanish tool measures infant pain rapidly and simply

North American legal injection drug site helps decrease overdose deaths, study shows

Researchers to wind down HIV prevention trial in women after interim results find drug not offering protection from HIV

Swinburne University of Technology acquires Elekta's Neuromag TRIUX MEG system

Diagnostic test Xpert MTB/RIF proven fast and effective in low-resource settings

Scientists detect several biomarkers to screen active drugs for Batten disease

Covidien supports FDA’s REMS for important class of pain medications

Diabetes in Control publishes complete list of drugs that affect blood glucose

Researchers deploy new tool in study of tubulin tyrosine ligase in tumor growth

Chronic inflammation due to infection may lead to cancer

Diabetes in Control announces clinical slide presentation library for medical community

MSF calls on African governments, WHO to switch to newer, more expensive treatment for severe malaria

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