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BIMR wins a GO grant from the National Institute of Mental Health

Thanks to a $50,000 grant from the California Bipolar Foundation (CBF) to post-doctoral research fellow Dr. Illyas Singec at the Burnham Institute for Medical Research (BIMR), a research team headed by Dr. Evan Snyder (along with co-investigators Drs. Dieter Wolfe and Lawrence Brill), was able to accumulate sufficient preliminary data to win an extremely competitive Grand Opportunities (GO) grant from the National Institute of Mental Health to explore the molecular basis of Bipolar Disorder (BPD).

19 Nov 2009

New biomarkers can predict patients' response to certain drugs

Recent advances in cancer therapeutics have led to the discovery of biomarkers that can predict patient response to certain drugs. Screening for mutations in the epidermal growth factor receptor (EGRF) prior to non-small cell lung cancer treatment, for example, has been shown to indentify patients who are likely to respond to treatment with erlontinib. This maximizes the drug's impact, and spares patients who are not likely to benefit from being subjected to potentially debilitating side effects.

19 Nov 2009

European Patent Office upholds Cellectis' EP 1 485 475 patent

Cellectis S.A., the French genome engineering specialist, has announced that the European Patent Office has today upheld European Patent EP 1 485 475 owned by Cellectis and relating to the invention of engineering methods for meganucleases. This method is based on the genetic fusion of meganuclease modules to obtain hybrid meganucleases.

19 Nov 2009

Queen’s University Belfast to study individualized radiotherapy treatment for breast cancer

Individualised radiotherapy treatment based on a person’s genetic make up could soon become a reality, according to Breast Cancer Campaign.

19 Nov 2009

New radical approach to test chemo drugs for potential toxic effects

Jackson Laboratory Professor Gary Churchill wants to change that. With a new two-year, $1 million grant from the National Cancer Institute, Churchill is launching a radical new approach to testing three chemotherapeutic drugs for potential toxic effects.

19 Nov 2009

Fully integrated human genome sequencing and data processing service launched

Knome, Inc., a recognized pioneer in the personal genomics field, today announced the launch of KnomeDISCOVERY, the first fully integrated human genome sequencing and data processing service for researchers. The new offering meets rapidly emerging demand from biomedical researchers for a one-stop service that bundles affordable, research-tailored access to a broad range of next-generation sequencing platforms with discovery-supportive data management and analysis.

18 Nov 2009

Data on Synta Pharmaceuticals' STA-9090 synthetic inhibitor of Hsp90 presented

Synta Pharmaceuticals Corp., a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to treat severe medical conditions, today announced that preclinical data presented at the AACR-NCI-EORTC Conference on Molecular Targets and Cancer Therapeutics shows that STA-9090, a novel, synthetic inhibitor of heat shock protein 90 (Hsp90), demonstrated strong activity in multiple tumor models.

18 Nov 2009

IBM scientists work with Rizzoli Orthopedic Institute to use BioMIMS to treat genetic skeletal diseases

IBM ( IBM) announced today that its Research scientists are working with the Rizzoli Orthopedic Institute, in Bologna, Italy, to use information technology to better address treatment and research for rare genetic skeletal diseases.

18 Nov 2009

Way to capture tumor cells in the bloodstream discovered

A team led by University of Arkansas for Medical Sciences (UAMS) researchers on the cutting edge of nanotechnology has found a way to capture tumor cells in the bloodstream that could dramatically improve earlier cancer diagnosis and prevent deadly metastasis.

18 Nov 2009

Researchers identify new way to capture tumor cells in bloodstream; findings can improve early cancer diagnosis

Jin-Woo Kim, a biomedical engineering researcher at the University of Arkansas, is part of a cutting-edge nanotechnology research group that has discovered a way to capture tumor cells in the bloodstream. The work could dramatically improve early cancer diagnosis and prevent deadly metastasis.

18 Nov 2009

VINNOVA to provide SEK 3.6 million for Vitrolife’s stem-cell research

Vitrolife: VINNOVA announced in a press release yesterday that they are going to provide support of SEK 3.6 million for Vitrolife’s research project for optimized culture media to enable the clinical use of stem cells. “It is very pleasing news and will enable more intensive work in an area that we very much believe in for the future”, says Magnus Nilsson, Vitrolife’s CEO.

18 Nov 2009

Cancer-fighting protein successfully placed directly into solid tumors and turned on

Experiments at the Pioneer Valley Life Sciences Institute (PVLSI) at Baystate Medical Center in Springfield, Mass., reported in a recent British Journal of Cancer, confirm that University of Massachusetts Amherst chemical engineer Neil Forbes' delivery and trigger system has for the first time successfully placed TRAIL, a cancer-fighting protein, directly into solid tumors and on cue, turned it on. The treatment improved the 30-day survival time of mice with mammary tumors from 0 to 100 percent.

18 Nov 2009

Cardiologists detect atherosclerosis in ancient Egyptian mummies

A cardiologist at Saint Luke's Mid America Heart Institute and his research colleagues from Cairo, Milwaukee, and Mission Viejo, Calif., have detected hardening of the arteries in 3,500-year-old Egyptian mummies, indicating that heart disease is not just a condition found in modern humans.

18 Nov 2009

Developmental biologists to participate in $100 million federal 'Bench to Bassinet' network

Developmental biologists at the University of Pittsburgh have been chosen to participate in a $100 million federal "Bench to Bassinet" network that is dedicated to learning about the formation of the cardiovascular system and applying that knowledge to create new diagnostic and intervention strategies for congenital heart disease.

18 Nov 2009

New neuroimaging techniques yield new insights on Alzheimer's disease

Brain imaging can offer a window into risk for diseases such as Alzheimer's disease (AD). A study conducted at the University of Kansas School of Medicine demonstrated that genetic risk is expressed in the brains of even those who are healthy, but carry some risk for AD. The results of this study are published in the November 2009 issue of the Journal of Alzheimer's Disease.

18 Nov 2009

FaceBase Consortium established to create encyclopedic database on facial birth defects

Researchers at the University of Pittsburgh and the University of Iowa will lead a $9 million, five-year initiative to study the cause of facial birth defects. The FaceBase Consortium will create an encyclopedic database of how the faces of children develop and what goes wrong to cause malformations.

18 Nov 2009

AMD: A leading cause of blindness among smokers

MD Alliance International strongly urges all smokers to participate in the Great American Smokeout on November 19 to save their eyes and protect their vision from the debilitating effects of macular degeneration.

18 Nov 2009

Almost half of the women in the UK suffer from lack of vitamin A, find scientists

Almost half of UK women could be suffering from a lack of vitamin A due to a previously undiscovered genetic variation, scientists at Newcastle University have found.

18 Nov 2009

Helicos Genetic Analysis System to be installed at the Leiden Genome Technology Center

Helicos BioSciences Corporation, today announced the sale of a Helicos® Genetic Analysis System to a collaborative Dutch research group led by the Leiden University Medical Center (LUMC), further including the medical centers of Amsterdam (AMC) Groningen (UMCG) and Rotterdam (Erasmus MC) and funded by a grant from NWO, the Netherlands Organization of Scientific Research.

17 Nov 2009

British citizenship based on the legal citizenship of the genetically linked parent

Last week's decision by chief justice KS Radhakrishnan and justice AS Dave in Gujarat, India, high court is still reverberating amongst the more than 300 medical clinics in India that are part of the estimated $5.2 billion assisted reproductive technology (ART) industry in that country.

17 Nov 2009

Genetic News and Research

BIMR wins a GO grant from the National Institute of Mental Health

New biomarkers can predict patients' response to certain drugs

European Patent Office upholds Cellectis' EP 1 485 475 patent

Queen’s University Belfast to study individualized radiotherapy treatment for breast cancer

New radical approach to test chemo drugs for potential toxic effects

Fully integrated human genome sequencing and data processing service launched

Data on Synta Pharmaceuticals' STA-9090 synthetic inhibitor of Hsp90 presented

IBM scientists work with Rizzoli Orthopedic Institute to use BioMIMS to treat genetic skeletal diseases

Way to capture tumor cells in the bloodstream discovered

Researchers identify new way to capture tumor cells in bloodstream; findings can improve early cancer diagnosis

VINNOVA to provide SEK 3.6 million for Vitrolife’s stem-cell research

Cancer-fighting protein successfully placed directly into solid tumors and turned on

Cardiologists detect atherosclerosis in ancient Egyptian mummies

Developmental biologists to participate in $100 million federal 'Bench to Bassinet' network

New neuroimaging techniques yield new insights on Alzheimer's disease

FaceBase Consortium established to create encyclopedic database on facial birth defects

AMD: A leading cause of blindness among smokers

Almost half of the women in the UK suffer from lack of vitamin A, find scientists

Helicos Genetic Analysis System to be installed at the Leiden Genome Technology Center

British citizenship based on the legal citizenship of the genetically linked parent

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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