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Scientists find link between Alzheimer's disease and chronic heart failure

A team of U.S., Canadian and Italian scientists led by researchers at Johns Hopkins report evidence from studies in animals and humans supporting a link between Alzheimer's disease and chronic heart failure, two of the 10 leading causes of death in the United States.

16 Nov 2009

Links present between Alzheimer's disease and chronic heart failure, support researchers

16 Nov 2009

Researchers develop software tools to search and compare patient data at hospitals across Europe

By matching children with rare or life-threatening diseases and modelling potential disease progression, researchers hope to find new routes forward.

16 Nov 2009

Some combination drug therapies are counter-productive

Combination drug therapy has become a staple for treating many infections. For instance, doctors treat extensively drug resistant forms of tuberculosis with one drug that breaks down the pathogen's protective barriers and opens the door for another to deliver the deathblow.

16 Nov 2009

Research team identifies five new gene regions that raise the risk of childhood-onset IBD

In the largest, most comprehensive genetic analysis of childhood-onset inflammatory bowel disease (IBD), an international research team has identified five new gene regions, including one involved in a biological pathway that helps drive the painful inflammation of the digestive tract that characterizes the disease.

16 Nov 2009

Easy and affordable genetic test from Pathway Genomics

Pathway Genomics™ (www.PATHWAY.com), a privately held, venture-backed company, today announced an exclusive agreement to partner with OptumHealthSM Allies and offer the organization’s 15 million members a 20% discount on Pathway’s Health and Ancestry genetic test.

13 Nov 2009

Poor mental health in children and teenagers impacts on the length of time they will stay in school: Study

"Our study shows that poor mental health in children and teenagers has a large impact on the length of time they will stay in school," says Dr. Lehrer. He notes a large number of school-based programs have recently been introduced to prevent childhood obesity through lifestyle changes, but suggests the net should be cast more widely. "It's important for policymakers to target health conditions that are not the easiest to identify - like inattention - but may have larger impacts on one's future."

13 Nov 2009

New software may help doctors to identify brain tumours in children that will grow aggressively

New software is under development that doctors hope will help them identify brain tumours in children that will grow aggressively.

13 Nov 2009

Scientists describe how HIV assemble at the membrane of infected cells and are released to attack healthy cells

Although recent advances have raised hopes that a protective vaccine can be developed, acquired immunodeficiency syndrome (AIDS) remains a major public health problem. Much has been learned about HIV-1, the virus that causes the disease.

13 Nov 2009

Scientists to develop a treatment for rare genetic disorder, FOP

An international team of scientists, led by researchers at the University of Pennsylvania School of Medicine, is taking the first step in developing a treatment for a rare genetic disorder called fibrodysplasia ossificans progressiva (FOP), in which the body's skeletal muscles and soft connective tissue turns to bone, immobilizing patients over a lifetime with a second skeleton.

13 Nov 2009

New findings on human genome may be useful for developing specific AIDS drugs

The AIDS virus inserts its genetic material into the genome of the infected cell. Scientists of the German Cancer Research Center have now shown for the first time that the virus almost entirely spares particular sites in the human genetic material in this process. This finding may be useful for developing new, specific AIDS drugs.

13 Nov 2009

Positive results from Lexicon Pharmaceuticals' LX1031 Phase 2 study for IBS

Lexicon Pharmaceuticals, Inc. announced today that the company's investigational new drug, LX1031, a tryptophan hydroxylase (TPH) inhibitor, demonstrated positive results in clinically important parameters for the treatment of non-constipating irritable bowel syndrome (IBS).

13 Nov 2009

Mouth: A diagnostic indicator for general health

The mouth or oral cavity area is an excellent indicator of the whole body's health, says Mao, who is the chair of the new Department of Oncology and Diagnostic Sciences at the School.

13 Nov 2009

UT Southwestern Medical Center awarded $42M for basic and patient-oriented research

UT Southwestern Medical Center has been awarded more than $42 million to date for basic and patient-oriented research from the American Recovery and Reinvestment Act of 2009, the $787 billion stimulus package President Barack Obama signed into law in February.

13 Nov 2009

IVF Witness uses RFID to identify the sperm and eggs, and reduces the risk of lab errors in infertility treatment

A new software technology is helping to reduce the risk of laboratory errors in infertility treatment, by electronically identifying the sperm, eggs, resulting embryos and other materials used in in vitro fertilization (IVF) treatment cycles. Using non-invasive Radio Frequency Identification (RFID), IVF Witness(TM) can track a patient's sperm, eggs and embryos during the course of treatment. If the wrong material is introduced in the lab environment, IVF Witness alerts the staff, via visual and audible signals, to help prevent mislabeling of any materials.

12 Nov 2009

Cequent Pharmaceuticals proposes the first test of an orally administered RNA interference drug in humans

Cequent Pharmaceuticals, a pioneer in the development of novel products to deliver RNAi-based treatments to prevent and treat human disease, has announced that it has filed its first IND (investigational new drug) application with the U.S. Food and Drug Administration (FDA).

12 Nov 2009

Update on Alnylam Pharmaceuticals' RNAi pipeline, platform, and technology

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, is providing an update on its RNAi pipeline, platform, and technology at its R&D Day being held in New York today.

12 Nov 2009

Gene variants which influence insulin metabolism can also affect birth weight

Low birth weight increases the risk of developing type 2 diabetes later in life. Until recently scientists had attributed this to maternal malnutrition during pregnancy. However, now it seems that genetic background may also play a major role. A research team of Technische Universität München and Helmholtz Zentrum München has now demonstrated, that gene variants which influence insulin metabolism can also affect birth weight.

12 Nov 2009

Co-founders of Signature Genomics recognized with Inland Northwest Catalyst Award

Signature Genomics, which performs diagnostic genetic testing of chromosome abnormalities in individuals with unexplained mental retardation and/or birth defects, today announced company co-founders Dr. Lisa G. Shaffer, Ph.D., and Dr. Bassem A. Bejjani, M.D. have received the 2009 Inland Northwest Catalyst Award for Innovators of the Year.

12 Nov 2009

PIKAMAB announces the development of ADCC Therasight, a novel theragnostic product

PIKAMAB, a stratified medicine biopharmaceutical company, announced today that it is developing ADCC TherasightTM, a novel theragnostic product that can help guide the drug development process and patient treatment protocols for the cancer therapeutic antibodies that use ADCC (antibody-dependent cellular cytotoxicity) as the major mechanism of action.

12 Nov 2009

Genetic News and Research

Scientists find link between Alzheimer's disease and chronic heart failure

Links present between Alzheimer's disease and chronic heart failure, support researchers

Researchers develop software tools to search and compare patient data at hospitals across Europe

Some combination drug therapies are counter-productive

Research team identifies five new gene regions that raise the risk of childhood-onset IBD

Easy and affordable genetic test from Pathway Genomics

Poor mental health in children and teenagers impacts on the length of time they will stay in school: Study

New software may help doctors to identify brain tumours in children that will grow aggressively

Scientists describe how HIV assemble at the membrane of infected cells and are released to attack healthy cells

Scientists to develop a treatment for rare genetic disorder, FOP

New findings on human genome may be useful for developing specific AIDS drugs

Positive results from Lexicon Pharmaceuticals' LX1031 Phase 2 study for IBS

Mouth: A diagnostic indicator for general health

UT Southwestern Medical Center awarded $42M for basic and patient-oriented research

IVF Witness uses RFID to identify the sperm and eggs, and reduces the risk of lab errors in infertility treatment

Cequent Pharmaceuticals proposes the first test of an orally administered RNA interference drug in humans

Update on Alnylam Pharmaceuticals' RNAi pipeline, platform, and technology

Gene variants which influence insulin metabolism can also affect birth weight

Co-founders of Signature Genomics recognized with Inland Northwest Catalyst Award

PIKAMAB announces the development of ADCC Therasight, a novel theragnostic product

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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