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MICAL2 enzyme found to promote tumor growth in pancreatic cancer

Pancreatic cancer kills 50,000 people each year, according to the National Cancer Institute, and there are few effective treatment options for the disease.

2 Jan 2025

Research reveals key to understanding kidney cancer treatment variability

Fighting cancer can seem like a deadly game of chance. While some patients may respond well to certain treatments, others might not be as fortunate.

2 Jan 2025

Histone markers predict human age with accuracy comparable to DNA methylation clocks

Researchers unveil histone-based age predictors, offering a new window into epigenetic aging and its shared patterns across tissues.

2 Jan 2025

Study reveals how fatty liver disease leads to liver cancer

Scientists at University of California San Diego School of Medicine have shed new light on the development of liver cancer, the sixth most frequently diagnosed cancer and fourth leading cause of cancer deaths worldwide.

2 Jan 2025

New insights into tristetraprolin's impact on basophil-mediated allergic inflammation

Inflammation is a crucial part of the body's defense mechanism, playing a key role in fighting infections and repairing tissue damage.

2 Jan 2025

Yale study identifies molecular mechanism behind some lissencephaly disorders

Lissencephaly is a spectrum of rare, genetic disorders in which the brain fails to develop its hallmark folds.

2 Jan 2025

Discovery of nuclear speckles may improve cancer treatment decisions

Fighting cancer can seem like a deadly game of chance. While some patients may respond well to certain treatments, others might not be as fortunate. Doctors and scientists have long struggled to explain why.

2 Jan 2025

New protein offers hope for heart regeneration

Researchers from the Bakkers group at the Hubrecht Institute have successfully repaired damaged mouse hearts using a protein from zebrafish.

2 Jan 2025

Skin explants reveal how Ebola virus moves through the body

Ebola is a deadly hemorrhagic disease caused by a virus that is endemic in parts of East-Central and West Africa. Most people are aware that a primary route for person-to-person transmission is through contact with bodily fluids from an infected person.

1 Jan 2025

Brain mapping reveals cell-specific aging patterns

Based on new brain mapping research funded by the National Institutes of Health (NIH), scientists have discovered that not all cell types in the brain age in the same way.

1 Jan 2025

Study uncovers aspartate's surprising role in lung metastases

Researchers from the lab of Prof. Sarah-Maria Fendt (VIB-KU Leuven) and colleagues have uncovered that the availability of the amino acid aspartate is one reason why the lung is a frequent organ of metastasis.

1 Jan 2025

Unraveling retrotransposon mechanisms in centromere insertion

A joint research group team led by Sayuri Tsukahara and Tetsuji Kakutani of the University of Tokyo has clarified a mechanism of how retrotransposons, genetic elements that can "jump around" chromosomes and are known drivers of evolution, preferentially insert in the centromere.

1 Jan 2025

Lithocholic acid enhances health and lifespan, mimicking calorie restriction

Lithocholic acid (LCA), a metabolite induced by calorie restriction (CR), activates AMPK and mimics anti-aging benefits. A recent study highlights LCA's role in improving muscle performance, glucose tolerance, and lifespan in aged organisms.

1 Jan 2025

Exploring new ways to improve treatment options for kidney cancer patients

A Medical University of South Carolina Hollings Cancer Center researcher is exploring new ways to improve treatment options for kidney cancer patients.

30 Dec 2024

Advancing Raman microscopy for high-resolution imaging of biological samples

Understanding the behavior of the molecules and cells that make up our bodies is critical for the advancement of medicine.

30 Dec 2024

Estrogen's role in female binge drinking revealed by preclinical study

The hormone estrogen regulates binge drinking in females, causing them to "pregame" – consume large quantities of alcohol in the first 30 minutes after it's offered, according to a preclinical study led by scientists at Weill Cornell Medicine.

30 Dec 2024

Investigating fatty acid metabolism in hepatocellular carcinoma patients

Announcing a new publication for Acta Materia Medica journal. Fatty acid (FA) reprogramming has a significant role in liver cancer. However, the contribution of FA metabolism reprogramming to the heterogeneity of hepatocellular carcinoma (HCC) has not been established.

30 Dec 2024