in vitro News and Research

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Novel drug candidate offers a major advance in the treatment for diabetes

The University of Alabama at Birmingham and Southern Research have discovered a new drug candidate that offers a major advance in the treatment for diabetes.

28 Jul 2020

TARA Biosystems and VantAI team up to accelerate drug development for cardiac disease

VantAI and TARA Biosystems today announced the launch of a biology-driven, AI-enabled collaboration for accelerated cardiac drug development.

28 Jul 2020

AI Therapeutics announces start of Phase II clinical trial of potential COVID-19 treatment

AI Therapeutics announced the start of Phase II clinical trial for the treatment of newly diagnosed COVID-19 patients in collaboration with Yale University.

27 Jul 2020

Clinical trials of hydroxychloroquine in COVID-19 outpatients reported as safe

According to new research, the use of hydroxychloroquine among outpatients in clinical trials, without high-risk factors for cardiac arrhythmia, is safe.

27 Jul 2020

High ACE2 Expression on pancreatic islet cells during inflammation could explain new-onset diabetes in COVID-19

A new study suggests that the SARS-CoV-2 infection may be linked to the onset of diabetes, via the infection of pancreatic islet beta cells, which produce insulin.

27 Jul 2020

Curi Bio Acquires Dana Solutions

Curi Bio has acquired Dana Solutions, a pioneer in the application of artificial intelligence and machine learning to in vitro cell-based assays.

From Curi Bio 27 Jul 2020

Researchers identify anticoagulation agent that suppresses SARS-CoV-2 replication in vitro

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can cause acute respiratory distress syndrome, hypercoagulability, hypertension, and multiorgan dysfunction.

27 Jul 2020

Researchers use new approach to unravel the mechanisms that lie behind tetraploidy

Cell division is a fundamental process that organisms need to reproduce, grow, and make repairs. But when an error disrupts this complex biological process, cellular abnormalities can lead to diseases, such as cancer, where cells are enabled to grow and divide out of control.

25 Jul 2020

Seaweed extract outperforms remdesivir in inhibiting SARS-CoV-2 in cell studies

In a test of antiviral effectiveness against the virus that causes COVID-19, an extract from edible seaweeds substantially outperformed remdesivir, the current standard antiviral used to combat the disease.

24 Jul 2020

An important SARS-CoV-2 enzyme is responsible for low in vivo antiviral efficacy of hydroxychloroquine

Researchers have shown that hydroxychloroquine interferes with only one redundant pathway that activates the SARS-CoV-2 spike protein.

24 Jul 2020

Hypertension drugs are associated with elevated incidence of heart failure

L-type calcium channel blockers (LCCBs) -- the most widely used drugs for treating hypertension -- may harm the heart as much as help it, according to a new study.

24 Jul 2020

Gene signature explains why 18F-FDG imaging performs better for PSMA-suppressed prostate cancer patients

Scientists have uncovered the genomic signature to explain why 18F-FDG imaging performs better than PSMA-targeted imaging for prostate cancer patients with low or no expression of the prostate-specific membrane antigen (PSMA).

23 Jul 2020

Neutralizing antibodies isolated from COVID-19 patients can quash SARS-CoV-2

Scientists across the globe are racing to study how antibodies can help suppress SARS-CoV-2, the virus that causes the coronavirus disease (COVID-19).

23 Jul 2020

Study shows interferons do not induce the expression of SARS-CoV-2 cell entry receptor

In a new bioRxiv study, authors identified a isoform of ACE2 (designated as deltaACE2 or dACE2) receptor, shown to be induced in various human cell types.

23 Jul 2020

Researchers recreate pancreatic cancer tissue using 3D-cell culture technique

Pancreatic cancer is a life-threatening disease with very poor survival rates in patients, and--despite various efforts--its treatment remains challenging.

23 Jul 2020

siRNA-based treatment can reduce psoriasis symptoms

Psoriasis, a chronic skin condition that causes itchy, red, scaly patches, afflicts more than 8 million Americans and 125 million people worldwide.

23 Jul 2020

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

in vitro News and Research

Novel drug candidate offers a major advance in the treatment for diabetes

TARA Biosystems and VantAI team up to accelerate drug development for cardiac disease

AI Therapeutics announces start of Phase II clinical trial of potential COVID-19 treatment

Clinical trials of hydroxychloroquine in COVID-19 outpatients reported as safe

High ACE2 Expression on pancreatic islet cells during inflammation could explain new-onset diabetes in COVID-19

Curi Bio Acquires Dana Solutions

Researchers identify anticoagulation agent that suppresses SARS-CoV-2 replication in vitro

Researchers use new approach to unravel the mechanisms that lie behind tetraploidy

Seaweed extract outperforms remdesivir in inhibiting SARS-CoV-2 in cell studies

An important SARS-CoV-2 enzyme is responsible for low in vivo antiviral efficacy of hydroxychloroquine

Hypertension drugs are associated with elevated incidence of heart failure

Gene signature explains why 18F-FDG imaging performs better for PSMA-suppressed prostate cancer patients

Neutralizing antibodies isolated from COVID-19 patients can quash SARS-CoV-2

Study shows interferons do not induce the expression of SARS-CoV-2 cell entry receptor

Researchers recreate pancreatic cancer tissue using 3D-cell culture technique

siRNA-based treatment can reduce psoriasis symptoms

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

Researchers assess the damage caused by microbubbles in brain injuries

SphingoTec introduces a CE-IVD-marked point-of-care test to determine blood levels of bio-ADM

Calcium channel subunits play a crucial role in neurological disorders

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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