Protein C News and Research

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New mechanism to enhance restoration of blood flow in ischemic diseases

In Nature, VIB-K.U.Leuven researchers describe a new mechanism to enhance the restoration of the blood flow in ischemic diseases, which are among the leading causes of death worldwide.

11 Oct 2011

WTSI announces new technique to reprogramme human cells

Researchers from the Wellcome Trust Sanger Institute today announce a new technique to reprogramme human cells, such as skin cells, into stem cells. Their process increases the efficiency of cell reprogramming by one hundred-fold and generates cells of a higher quality at a faster rate.

11 Oct 2011

Scripps Research receives NIH grant to determine how HCV induces liver cancer

The Scripps Research Institute has been awarded a $2.2 million grant by the National Institutes of Health (NIH) to determine how the hepatitis C virus (HCV) induces liver cancer.

11 Oct 2011

Normal Htt protein regulates formation of cellular structures in mouse model of HD

Huntington disease is a devastating neurogenerative disorder that causes a progressive loss of functional capacity and reduced life span. It is an inherited condition caused by a mutant HTT gene. Although this has been known for many years, the functions of the normal Htt protein and the mechanisms by which the mutant protein generated from the mutant HTT gene causes disease are not well understood.

11 Oct 2011

Sirt1 protein enhances skeletal muscle insulin sensitivity in calorie-restricted mice

The number of individuals with type 2 diabetes is reaching epidemic proportions. One of the main risk factors for developing type 2 diabetes is resistance of cells in the body (particularly liver, fat, and skeletal muscle cells) to the effects of the hormone insulin.

11 Oct 2011

CXCL12 protein can inhibit metastasis of colon and melanoma cancers

Researchers at the Medical College of Wisconsin have shown that a protein can inhibit metastasis of colon and melanoma cancers. The findings are published in the October 10, 2011 issue of Proceedings of the National Academy of Sciences.

11 Oct 2011

Positive results from Biotron's BIT225 Phase 2a trial on HCV

Australian drug development company Biotron Limited has released headline results from its landmark Phase 2a trial of its lead drug candidate, BIT225 in Hepatitis C virus (HCV) infected patients.

11 Oct 2011

FDA clears Cardium's new Excellagen topical gel for diabetic foot ulcers

Cardium Therapeutics announced today that it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market and sell the Company's new Excellagen professional-use, sterile, syringe-based advanced wound care product for the management of diabetic foot ulcers and other dermal wounds.

11 Oct 2011

Coridon demonstrates 100% protection using DNA HSV-2 vaccine

DNA vaccine development company Coridon Pty Ltd. today announced that it had successfully completed pre-clinical efficacy testing of its prototype Herpes Simplex Virus 2 (HSV-2) vaccine, with outstanding results. The company will now look to progress the program into clinical studies.

10 Oct 2011

Cardium's Excellagen topical gel for diabetic foot ulcers receives FDA 510(k) clearance

Cardium Therapeutics announced today that it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market and sell the Company's new Excellagen™ professional-use, sterile, syringe-based advanced wound care product for the management of diabetic foot ulcers and other dermal wounds.

10 Oct 2011

VGX International, Inovio partner to co-develop SynCon vaccines for hepatitis B and C infections

Inovio Pharmaceuticals, Inc., a leader in the development of synthetic vaccines against cancers and infectious diseases, announced today that it has entered into a product development collaboration agreement with its affiliate, VGX International Inc., to co-develop Inovio's SynCon therapeutic vaccines for hepatitis B and C infections.

10 Oct 2011

Researchers examine effects of antirejection drugs in kidney transplant patients

Modern medicine's ability to save lives through organ transplantation has been revolutionized by the development of drugs that prevent the human body from rejecting the transplanted organ.

10 Oct 2011

New siRNA treatment reduces damaging inflammation in animals models of several disorders

Massachusetts General Hospital (MGH) researchers - along with collaborators from Massachusetts Institute of Technology (MIT) and Alnylam Pharmaceuticals - have found a way to block, in an animal model, the damaging inflammation that contributes to many disease conditions.

10 Oct 2011

First successful quantification of membrane lipids in a living cell

Could controlling cell-membrane fat play a key role in turning off disease? Researchers at the University of Illinois at Chicago think so, and a biosensor they've created that measures membrane lipid levels may open up new pathways to disease treatment.

10 Oct 2011

Advocates prepare for battle on PSA testing; insurers review options

A day after a government panel said that healthy men should no longer get screened for prostate cancer, some doctors' groups and cancer patients' advocates began a campaign to convince the nation that the advice was misguided. Their hope is to copy the success of women's groups that successfully persuaded much of the country two years ago that it was a mistake for the same panel, the United States Preventive Services Task Force, to recommend against routine mammograms for women in their 40s.

10 Oct 2011

Researchers identify cellular pathway to potentially block disease-inducing inflammation

Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, psoriasis, inflammatory bowel disease, and multiple sclerosis. Understanding the details of this pathway may provide opportunities for tailored treatments of inflammatory and autoimmune diseases.

10 Oct 2011

Preventive task force panel will urge men to skip prostate screening, reports say

The U.S. Preventive Services Task Force is scheduled to issue this recommendation on Tuesday, but advance press reports indicate the expert panel will urge the federal government to change its current position to recommend that men under age 75 forgo this widely used test.

7 Oct 2011

Nutrition tips for long-distance runners

With marathon trainees about to take to the streets of Chicago this Sunday, Loyola University Health System registered dietitian Brooke Schantz offers the top 10 nutrition tips runners can follow to help them cross the finish line.

7 Oct 2011

USPTO awards HistoRx two patents for methods of standardization of digital microscopy instruments

HistoRx, the leader in quantitative immunohistochemistry, advances its proprietary position in digital pathology through the recent issuance of US patents covering key features necessary for achievement of reproducible, standardized image analysis results.

7 Oct 2011

Calcium supplementation does not benefit pregnant women, except for hypertension

Most physicians instruct pregnant women to increase their calcium intake, but a new evidence review of potential benefits of calcium supplementation for mom and baby found none, except for the prevention of pregnancy-related hypertension.

7 Oct 2011

Protein C News and Research

New mechanism to enhance restoration of blood flow in ischemic diseases

WTSI announces new technique to reprogramme human cells

Scripps Research receives NIH grant to determine how HCV induces liver cancer

Normal Htt protein regulates formation of cellular structures in mouse model of HD

Sirt1 protein enhances skeletal muscle insulin sensitivity in calorie-restricted mice

CXCL12 protein can inhibit metastasis of colon and melanoma cancers

Positive results from Biotron's BIT225 Phase 2a trial on HCV

FDA clears Cardium's new Excellagen topical gel for diabetic foot ulcers

Coridon demonstrates 100% protection using DNA HSV-2 vaccine

Cardium's Excellagen topical gel for diabetic foot ulcers receives FDA 510(k) clearance

VGX International, Inovio partner to co-develop SynCon vaccines for hepatitis B and C infections

Researchers examine effects of antirejection drugs in kidney transplant patients

New siRNA treatment reduces damaging inflammation in animals models of several disorders

First successful quantification of membrane lipids in a living cell

Advocates prepare for battle on PSA testing; insurers review options

Researchers identify cellular pathway to potentially block disease-inducing inflammation

Preventive task force panel will urge men to skip prostate screening, reports say

Nutrition tips for long-distance runners

USPTO awards HistoRx two patents for methods of standardization of digital microscopy instruments

Calcium supplementation does not benefit pregnant women, except for hypertension

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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