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New platform for analysis of next generation sequencing data developed by Compugen

Compugen Ltd. (NASDAQ: CGEN) announced today the development of "NexGen," a new platform designed to significantly enhance Compugen’s overall infrastructure for predictive drug and drug target discovery. NexGen is designed to analyze Next Generation Sequencing data which is now beginning to be generated worldwide through RNA-Seq methodology.

2 Jul 2012

Blocking AXL protein may prevent resistance to lung cancer drug

People with lung cancer who are treated with the drug Tarceva face a daunting uncertainty: although their tumors may initially shrink, it's not a question of whether their cancer will return—it's a question of when. And for far too many, it happens far too soon.

2 Jul 2012

Study tracks changes in spending, prices, and use of health care services by children

Spending on health care for children grew faster than spending for adults between 2007 and 2010 due to increasing prices for all categories of goods and services, finds a new report from the Health Care Cost Institute (HCCI).

2 Jul 2012

Clinical results for Teva's biologic oncology candidates presented at MASCC/ISOO 2012

Teva Pharmaceutical Industries Ltd. announced today the presentation of clinical results for its biologic oncology candidates, lipegfilgrastim and balugrastim, at the Multinational Association of Supportive Care in Cancer (MASCC)/International Society of Oral Oncology (ISOO) 2012 International Symposium on Supportive Care in Cancer being held in New York June 28-30.

2 Jul 2012

Rutgers explains significance of Supreme Court upholding the health care law

The Supreme Court upheld the core of President Obama's health care overhaul, ruling that the government can require all Americans to obtain health insurance or pay a penalty.

2 Jul 2012

Smokers with COPD may find relief with cystic fibrosis drug

A drug developed to treat certain strains of cystic fibrosis may be useful in the treatment of chronic obstructive pulmonary disease, one of the most common lung diseases, which is seen frequently in smokers and has no cure. The findings were published online Friday, June 29, 2012 in the online journal PLoS ONE by researchers at the University of Alabama at Birmingham.

30 Jun 2012

Blocking bombesin/GRP receptor improves survival in sepsis animal models

Septic shock is the most severe outcome associated with pathogen infection in the bloodstream. It is a life-threatening condition invariably leading to multiple organ dysfunctions. Currently, septic shock is one of the most frequent causes of death in intensive care units worldwide.

30 Jun 2012

Study details canonical Wnt signaling pathway

Many lung cancers are driven by mutations in the epidermal growth-factor receptor (EGFR), and so it makes sense that many successful modern treatments block EGFR activity. Unfortunately, cancers inevitably evolve around EGFR inhibition, and patients with lung cancers eventually relapse.

30 Jun 2012

Researchers discover new gene mutations associated with megalencephaly

A research team led by Seattle Children's Research Institute has discovered new gene mutations associated with markedly enlarged brain size, or megalencephaly.

30 Jun 2012

Oxytocin levels linked to medication dose, symptoms in schizophrenia

Higher doses of second-generation antipsychotics and more severe negative symptoms are associated with lower levels of oxytocin in cerebrospinal fluid among patients with schizophrenia, researchers report.

29 Jun 2012

$Epilepsy patients unaware of fracture risk$

Epilepsy patients unaware of fracture risk

Few patients with epilepsy are aware that taking anti-epileptic drugs puts them at increased risk for falls and fractures, report researchers.

29 Jun 2012

Eight-year trends in pediatric drug use examined

A review of US outpatient pediatric drug use over the past 8 years shows a decrease in systemic antibiotic, allergy, pain, and depression prescriptions, and an increase in asthma, attention deficit/hyperactivity disorder, and contraceptive prescriptions.

29 Jun 2012

$Study sheds light on increased risk of fractures and falls among epilepsy patients using AEDs$

Study sheds light on increased risk of fractures and falls among epilepsy patients using AEDs

New research has shed light on the high risk of fractures, falls, and osteoporosis among epilepsy patients using antiepileptic drugs (AEDs) with most patients unaware of the risks associated with taking the drugs.

29 Jun 2012

Scientists successfully tag serotonin transporter to track movements of single molecules

In a process akin to belling an infinitesimal cat, scientists have managed to tag a protein that regulates the neurotransmitter serotonin with tiny fluorescent beads, allowing them to track the movements of single molecules for the first time.

29 Jun 2012

UCSD surgeon first in the U.S. to implant new FDA-approved LINX for GERD

Santiago Horgan, MD, chief of minimally invasive surgery at UC San Diego Health System was the first surgeon in the United States to implant the new FDA-approved LINX for GERD.

29 Jun 2012

UMass Amherst biochemist receives NIH grant to map molecular structure of bacterial needle

Biochemist Alejandro Heuck at the University of Massachusetts Amherst recently received a five-year, $950,000 grant from the National Institutes of Health to map the molecular structure of a needle-like tool used by deadly bacteria to drill holes in mammalian cell walls.

29 Jun 2012

Stanford Medical School comment on Supreme Court ruling on health-care reform law

Today’s Supreme Court ruling on the Patient Protection and Affordable Care Act of 2010 advances the broad effort to extend health-care coverage and control medical costs, though it raises questions about how certain provisions of the policy will be implemented, Stanford University School of Medicine experts said. Here are some initial comments on the court’s landmark decision.

29 Jun 2012

Drug trial participants should be better informed about benefits and side-effects of placebos

Research carried out at the University of Southampton has concluded that participants in drug trials should be better informed about the potential significant benefits and possible side-effects of placebos.

29 Jun 2012

Researchers identify genes that influence degeneration of the hippocampus

In a genome-wide association (GWA) study, researchers from Boston University Schools of Medicine (BUSM) and Public Health (BUSPH) have identified several genes which influence degeneration of the hippocampus, the part of the brain most associated with Alzheimer disease (AD).

29 Jun 2012

New device for welding large and liquid-filled TPE tubing

Sartorius Stedim Biotech, a leading international supplier for the pharma and biotech industries, has launched the BioWelder® Total Containment (TC).

From Sartorius 29 Jun 2012

Drugs News and Research

New platform for analysis of next generation sequencing data developed by Compugen

Blocking AXL protein may prevent resistance to lung cancer drug

Study tracks changes in spending, prices, and use of health care services by children

Clinical results for Teva's biologic oncology candidates presented at MASCC/ISOO 2012

Rutgers explains significance of Supreme Court upholding the health care law

Smokers with COPD may find relief with cystic fibrosis drug

Blocking bombesin/GRP receptor improves survival in sepsis animal models

Study details canonical Wnt signaling pathway

Researchers discover new gene mutations associated with megalencephaly

Oxytocin levels linked to medication dose, symptoms in schizophrenia

Epilepsy patients unaware of fracture risk

Eight-year trends in pediatric drug use examined

Study sheds light on increased risk of fractures and falls among epilepsy patients using AEDs

Scientists successfully tag serotonin transporter to track movements of single molecules

UCSD surgeon first in the U.S. to implant new FDA-approved LINX for GERD

UMass Amherst biochemist receives NIH grant to map molecular structure of bacterial needle

Stanford Medical School comment on Supreme Court ruling on health-care reform law

Drug trial participants should be better informed about benefits and side-effects of placebos

Researchers identify genes that influence degeneration of the hippocampus

New device for welding large and liquid-filled TPE tubing

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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