Genetic News and Research

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Study on childhood risk factors for the development of future substance use disorders

There is ample evidence for the genetic influence of alcohol dependence, and ongoing studies are actively looking for specific genes that may confer this increased susceptibility. In addition, while it is well-known that individual risk is increased with the number of relatives with alcohol dependence, scientists have not been in a position to identify who among these individuals might have greater or lesser risk.

21 Oct 2009

Shire to file a Biologics License Application for REPLAGAL with the FDA

Shire plc, the global specialty biopharmaceutical company, announces plans to file a Biologics License Application (BLA) with the U.S. Food and Drug Administration (FDA) for REPLAGAL(R) (agalsidase alfa), its enzyme replacement therapy for Fabry disease, by the end of the year.

21 Oct 2009

NIH awards $2.1 million to a team of scientists for schizophrenia research

The US National Institutes of Health (NIH) has awarded a $2.1 million "Grand Opportunity" (GO) grant to a team of researchers - led by Prof. Todd Lencz at the Feinstein Institute for Medical Research, New York, and Prof.Ariel Darvasi of the Silberman Institute of Life Sciences at the Hebrew University of Jerusalem - to conduct a study on the genetic basis of schizophrenia..

21 Oct 2009

Autobiography of a cardiologist "Doctor of the Heart" published

Doctor of the Heart: My Life in Medicine is the autobiography of Isadore Rosenfeld, MD, world-renowned cardiologist, best-selling author, and popular television commentator. Published by Mary Ann Liebert, Inc., Dr. Rosenfeld's book is a remarkable account of his long and extraordinary career (www.liebertpub.com/heart).

21 Oct 2009

Roche NimbleGen and High Throughput Genomics enter into a supply agreement

Roche NimbleGen and High Throughput Genomics, Inc. (HTG), provider of the quantitative Nuclease Protection Assay (qNPA), have entered into a supply agreement. Under the agreement, Roche NimbleGen will provide HTG with high density, multiplex DNA microarray slides for advanced gene expression analysis.

21 Oct 2009

STR genotyping and p57 immunohistochemistry used to distinguish hydatidiform moles

Researchers from The Johns Hopkins Medical Institutions have used short tandem repeat (STR) genotyping and p57 immunohistochemistry to distinguish hydatidiform moles.

21 Oct 2009

Book reviews applications of genetic research in the fields of exercise science and sports medicine

This publication reviews past, current and future applications of genetic research in the fields of exercise science and sports medicine. It highlights ethical concerns, potential clinical applications and exploitation of genetic information. The authors, an interdisciplinary group of experts comprising clinicians, exercise scientists, human geneticists and other biological scientists, present an integrated and holistic understanding of the field to the reader.

21 Oct 2009

Genomes of two E. coli bacteria strains sequenced and analyzed

An international team of researchers from the United States, Korea, and France has sequenced and analyzed the genomes of two important laboratory strains of E. coli bacteria, one used to study evolution and the other to produce proteins for basic research or practical applications. The findings will help guide future research and will also open a window to a deeper understanding of classical research that is the foundation of our understanding of basic molecular biology and genetics.

21 Oct 2009

Innovative way to keep produce and flowers fresh for longer periods of time

Did you know that millions of tons of fruits and vegetables in the United States end up in the trash can before being eaten, according to the U.S. Department of Agriculture?

21 Oct 2009

Rice University scientists win NIH stimulus funds to study influenza A

Rice University scientists have won a $1.5 million grant from the National Institutes of Health to scrutinize the influenza A virus for clues that could lead to more effective antiviral drugs. Strains of influenza A include this year's pandemic H1N1 variety, some seasonal varieties and the much-feared H5N1 bird flu.

21 Oct 2009

New research highlights brain's vulnerability to obesity

New research released today is affirming a long-held maxim: you are what you eat - and, more to the point, what you eat has a profound influence on the brain. The findings offer insight into the neurobiological factors behind the obesity epidemic in the United States and other developed countries.

20 Oct 2009

TechnoVax receives NIH grant to further the development of its VLP-based, vaccine program

TechnoVax, Inc., a biotechnology developer of novel vaccines was awarded a three-year $2.9 million SBIR phase II grant from the National Institutes of Health to further the development of its VLP-based, vaccine program.

20 Oct 2009

Novavax, Avimex and GE Healthcare initiate clinical study of H1N1 VLP influenza vaccine

Novavax, Inc. (Nasdaq: NVAX) announced today that it has initiated a two-stage clinical study of its virus-like-particle (VLP) H1N1 influenza vaccine in Mexico in collaboration with Avimex Laboratories (Avimex) and GE Healthcare.

20 Oct 2009

Clonality analyses may lead to further understanding of hepatocarcinogenesis

Focal nodular hyperplasia (FNH) is a lesion found in an otherwise normal liver, and is considered to be parenchyma overgrowth responsive to increased blood flow secondary to vascular malformations.

20 Oct 2009

Substantial price reduction for 24 Chromosome Aneuploidy Screening

Gene Security Network, Inc. (GSN) today announced a substantial price reduction for its 24 Chromosome Aneuploidy Screening with Parental SupportTM. Effective immediately, pricing has been restructured to a single flat fee for testing of up to 24 embryos in an in vitro fertilization (IVF) cycle.

20 Oct 2009

New technique to treat metabolic disorders in babies while still in the womb

Researchers say a new development in cord blood transplants for inherited metabolic disorders may be curative for some babies who are treated while still in the womb.

20 Oct 2009

Sigma-Aldrich launches SAGEspeed, a program for developing human disease models in rodents

Sigma-Aldrich® (Nasdaq: SIAL) today announced the launch of SAGEspeed(TM), a program to develop human disease models in rodents using its proprietary novel CompoZr(TM) Zinc Finger Nuclease (ZFN) gene editing technology (http://www.compozrzfn.com).

19 Oct 2009

Schering-Plough to present data on boceprevir at the AASLD 2009 Annual Meeting

Schering-Plough announced that data on boceprevir, an investigational hepatitis C virus (HCV) protease inhibitor, will be reported in an oral presentation at the American Association for the Study of Liver Diseases (AASLD) Annual Meeting in Boston, Oct. 30-Nov. 3.

19 Oct 2009

Metabolic master switch sets the biological clock in body tissues

Our body's activity levels fall and rise to the beat of our internal drums-the 24-hour cycles that govern fundamental physiological functions, from sleeping and feeding patterns to the energy available to our cells. Whereas the master clock in the brain is set by light, the pacemakers in peripheral organs are set by food availability. The underlying molecular mechanism was unknown.

19 Oct 2009

Viriom picks ChemDiv's Russian subsidiary for development of innovative HIV compounds

ChemDiv, Inc. of San Diego has proudly announced that its wholly owned subsidiary Chemical Diversity Research Institute (CDRI ) of Moscow, Russia, has been chosen by Viriom Ltd. ( Viriom) of Moscow, Russia as a service partner in developing innovative HIV compounds. The program includes pre-clinical and clinical studies, which are expected to begin in 2010.

19 Oct 2009