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Positive preliminary results from Alnylam's Phase I ALN-PCS trial on severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today the achievement of positive preliminary results from its ongoing clinical trial of ALN-PCS, an RNAi therapeutic targeting PCSK9 for the treatment of severe hypercholesterolemia.

5 Jan 2012

Scientists determine structure of endomannosidase enzyme

Scientists have determined the structure of the enzyme endomannosidase, significantly advancing our understanding of how a group of devastating human viruses including HIV and Hepatitis C hijack human enzymes to reproduce and cause disease.

4 Jan 2012

$Viamet commences VT-464 Phase 1/2 trial in castration-refractory prostate cancer$

Viamet commences VT-464 Phase 1/2 trial in castration-refractory prostate cancer

Viamet Pharmaceuticals, Inc., announced today that dosing has begun in a Phase 1/2 clinical trial of VT-464, an oral, potent and lyase-selective CYP17 inhibitor for the treatment of castration-refractory prostate cancer.

4 Jan 2012

Veloxis commences LCP-Tacro Phase IIIb study in kidney transplant patients

Veloxis Pharmaceuticals A/S today announced dosing of the first patient in the STRATO (Switching kidney TRAnsplant patients with Tremor to LCP-tacrO) Phase IIIb study of LCP-Tacro in kidney transplant recipients experiencing drug-induced tremors.

4 Jan 2012

NovaSterilis awarded soft tissue processing patent

NovaSterilis Inc., specializing in developing applications for supercritical carbon dioxide, has been granted US Patent 8,034,288 B2. The patent, dated October 11, 2011 entitled “Method and Apparatus for Cleaning of Viable Donor Soft Tissue”, covers a new method for cleaning soft allograft tissue including tendon, fascia, and skin with a supercritical fluid, thus avoiding other harmful chemical solvents that may leave residual chemicals.

4 Jan 2012

Task force identifies key themes and challenges in critical care research

To reduce mortality and improve patient care in the nation's ICUs, a task force formed by the Critical Care Societies Collaborative (CCSC), in conjunction with the US Critical Illness and Injury Trials Group (USCIITG) has recommended that research in the field become less fragmented and better account for patient heterogeneity and the complexity of critical illness.

4 Jan 2012

Shorter Chk1 protein neutralizes longer sibling to potentially benefit cancer patients

Scientists have found at least one instance when the smaller sibling gets to call the shots and cancer patients may one day benefit.

4 Jan 2012

MTR technique indicates that COPAXONE therapy results in tissue repair in RRMS patients

Researchers utilizing an advanced magnetic resonance imaging (MRI) technology to characterize and chart the evolution of MS lesions found that relapsing-remitting multiple sclerosis (RRMS) patients treated with COPAXONE (glatiramer acetate injection) experienced significantly increased magnetization transfer ratio.

4 Jan 2012

ASE/EAE issue recommendations on image acquisition using 3DE

For the first time, a joint committee of the European Association for Echocardiography and the American Society of Echocardiography have issued recommendations on image acquisition using three-dimensional echocardiography.

4 Jan 2012

Antigen Express to move AE37 cancer vaccine into larger clinical trials

Generex Biotechnology Corporation today provided an update to the clinical development & regulatory strategy for its cancer vaccine, AE37.

4 Jan 2012

USPTO issues patent to NJIT's unique device for treatment of brain injury

NJIT Professor Gordon Thomas and NJIT Research Professor Reginald Farrow, both in the department of physics, and NJIT alumnus Sheng Liu, formerly a doctoral student of both researchers and now an engineer at a biotech company, were awarded a patent today for the NJIT SmartShunt-, a unique device to help patients with brain injuries.

4 Jan 2012

Quest Diagnostics to acquire S.E.D. Medical Labs

S.E.D. Medical Laboratories will soon become part of Quest Diagnostics Incorporated, the world leader in diagnostic testing, information and services, through a definitive agreement signed today by Lovelace Health System and Quest Diagnostics.

From Quest Diagnostics 4 Jan 2012

Neogen develops new Reveal Q+ test for deoxynivalenol

Neogen Corporation has developed a new test for deoxynivalenol (DON) that combines the speed and simplicity of a lateral flow test with the fully quantitative precision of a more demanding testing method.

4 Jan 2012

iCAD enters $15M debt facility agreement with Deerfield Management

iCAD, Inc., an industry-leading provider of advanced image analysis, workflow solutions and radiation therapy for the early identification and treatment of cancer, today announced that it has entered into a five year, $15 million debt facility agreement with Deerfield Management Company LP, a leading healthcare investment fund.

3 Jan 2012

First Edition: January 3, 2012

In today's headlines, reports that New York seniors are experiencing reduced prescription coverage and more California patients are being added to the health insurance rolls.

3 Jan 2012

Aging suit from MIT to raise empathy for the elderly

A team of researchers in MIT's Agelab have created a suit to help people understand what it might be like to be in the shoes of an elderly person – literally. Called AGNES (Age Gain Now Empathy System), the suit replicates what it might be like to be in a 75-year-old body, replicating dexterity, flexibility, motor, and visual elements into a suit that can be worn by people of all ages.

3 Jan 2012

Bird flu updates

The latest bird flu virus that killed a 39-year-old bus driver in the southern Chinese city of Shenzhen over the weekend is not yet transmissible between humans, Chinese health authorities said. The man, who lived in Shenzhen just across the border from Hong Kong, died from multi-organ failure on Saturday, a week after being admitted to hospital with a fever brought on by the virus, state media reported.

3 Jan 2012

Regeneron, Genentech enter non-exclusive license and partial settlement agreement for EYLEA

Regeneron Pharmaceuticals, Inc. today announced that the Company has entered into a non-exclusive license and partial settlement agreement with Genentech, Inc., a member of the Roche Group relating to U.S. ophthalmic sales of EYLEA (aflibercept) Injection.

3 Jan 2012

Cutera to purchase assets of IRIDEX' global aesthetic business

Cutera, Inc. and IRIDEX Corporation today announced that the companies have entered into a binding agreement for Cutera to purchase certain assets of IRIDEX' global aesthetic business for approximately $5.1 million.

3 Jan 2012

Lundbeck invests in Ossianix to focus on biotherapeutics for CNS disorders

Ossianix, Inc. today announced a strategic investment by H. Lundbeck A/S in the form of a Convertible Promissory Note. The proceeds from Lundbeck's investment is expected to allow Ossianix to generate biopharmaceuticals for the treatment of nervous system disorders by utilizing Ossianix's proprietary single domain antibody platform modeled on the shark vNAR structure.

3 Jan 2012