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mRNA rabies vaccine induces durable immune response in macaques

Novel mRNA vaccine for rabies shows enhanced immune response with higher antibody levels and improved cross-neutralization, indicating potential for a broadly protective vaccine against related lyssavirus strains.

26 Jun 2023

IgA nephropathy: The disease that lies outside the kidney

The cause of a common kidney disease likely lies outside the kidney, according to a new study led by Columbia University researchers.

23 Jun 2023

Parental loss at a young age affects a person’s immune system later in life

When a person loses a parent or a caregiver at a young age, their immune system suffers later in life, according to University of Michigan research.

21 Jun 2023

Study concludes a single intramuscular injection of adintrevimab provides prophylactic efficacy against COVID-19 without safety concerns

Researchers evaluated the prophylactic immune protection conferred by a single intramuscular injection of adintrevimab (ADG20) against symptomatic COVID-19.

16 Jun 2023

A new weapon against COVID: RBD-62 protein shows promising results in preventing severe disease

Researchers used aerosolized receptor binding domain (RBD)-62 with 1,000-fold enhanced binding affinity.

15 Jun 2023

What is the impact of maternal SARS-CoV-2 booster vaccination on antibodies in blood and breast milk?

Researchers investigated the impact of maternal COVID-19 vaccination on SARS-CoV-2 antibodies.

15 Jun 2023

From delicacy to danger: The rising tide of shellfish allergies in children revealed

Shellfish consumption is on the rise, but so are shellfish allergies, particularly among children. A recent review delves into the epidemiology, symptoms, diagnosis, and management of shellfish allergies, highlighting the need for improved diagnostic tools and potential allergen immunotherapy.

13 Jun 2023

Manipulating white blood cells to eliminate solid tumors

By silencing the molecular pathway that prevents macrophages from attacking our own cells, Penn Engineers have manipulated these white blood cells to eliminate solid tumors.

12 Jun 2023

Study suggests the role of histamine-releasing factor in severe asthma and RV-induced asthma exacerbation

Asthma is more dangerous than many people realize. An estimated 10 Americans die everyday from asthma, and the disease leads to around 439,000 hospitalizations and 1.3 million emergency room trips each year.

12 Jun 2023

Study reveals factors impacting pertussis antibody half-lives in infants, sheds light on preterm infants' resilience

Researchers compared two methods of half-life estimation to evaluate the half-life of maternal antibodies.

9 Jun 2023

Patients with high-risk chronic lymphocytic leukemia may benefit from treatment with ibrutinib plus venetoclax

First-line ibrutinib (Imbruvica) plus venetoclax (Venclexta) led to high response and survival rates in patients with chronic lymphocytic leukemia (CLL) whether or not their cancer harbored high-risk genetic features typically associated with poor outcomes, according to results published in Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR).

7 Jun 2023

A SARS-CoV-2 spike-targeting bispecific T-cell engager strategy for controlling SARS-CoV-2 infection

Researchers described a novel strategy for controlling severe acute respiratory syndrome coronavirus 2.

5 Jun 2023

MFAP5, a microfibril-associated protein, unveiled as key player in scar formation and wound healing

MFAP5, a microfibril-associated protein, plays a significant role in wound healing by regulating fibroblast function, collagen deposition, and angiogenesis, suggesting its potential as a modulator of scar formation.

1 Jun 2023

Key insights into immune responses after COVID-19 vaccination in Indigenous people

Researchers evaluated immune responses to COVID-19 BNT162b2 mRNA vaccinations among Indigenous Australian First Nations (FN) individuals by comorbidity and ethnicity.

1 Jun 2023

What was SARS-CoV-2 antibody seroprevalence in Italian blood donors?

Researchers evaluated titers and types of severe acute respiratory syndrome coronavirus 2 antibodies in voluntary blood donors.

1 Jun 2023

Dutch scientists unveil the integral role of CD5L protein in IgM structure and function

Researchers in the Netherlands assessed the structure of human circulatory IgM and its relationship with the small CD5L protein.

31 May 2023

Green Mediterranean diet reshapes DNA methylation, boosts metabolism

Study explores the effects of a green-MED diet enriched in polyphenols and reduced in red/processed meat on the methylome and transcriptome levels. It aims to uncover the molecular mechanisms underlying the observed metabolic improvements.

30 May 2023

Study shows how IgA acts as a "tuner" to keep the immune system in check

IgA deficiency is the most common primary immune deficiency worldwide, but its presentation has puzzled physcians and researchers.

26 May 2023

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2.

26 May 2023

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Researchers develop a lipid nanoparticle-formulated mRNA-based antigen encoding three SARS-CoV-2 peptides derived from non-structural proteins.

25 May 2023

Immunoglobulin News and Research

mRNA rabies vaccine induces durable immune response in macaques

IgA nephropathy: The disease that lies outside the kidney

Parental loss at a young age affects a person’s immune system later in life

Study concludes a single intramuscular injection of adintrevimab provides prophylactic efficacy against COVID-19 without safety concerns

A new weapon against COVID: RBD-62 protein shows promising results in preventing severe disease

What is the impact of maternal SARS-CoV-2 booster vaccination on antibodies in blood and breast milk?

From delicacy to danger: The rising tide of shellfish allergies in children revealed

Manipulating white blood cells to eliminate solid tumors

Study suggests the role of histamine-releasing factor in severe asthma and RV-induced asthma exacerbation

Study reveals factors impacting pertussis antibody half-lives in infants, sheds light on preterm infants' resilience

Patients with high-risk chronic lymphocytic leukemia may benefit from treatment with ibrutinib plus venetoclax

A SARS-CoV-2 spike-targeting bispecific T-cell engager strategy for controlling SARS-CoV-2 infection

MFAP5, a microfibril-associated protein, unveiled as key player in scar formation and wound healing

Key insights into immune responses after COVID-19 vaccination in Indigenous people

What was SARS-CoV-2 antibody seroprevalence in Italian blood donors?

Dutch scientists unveil the integral role of CD5L protein in IgM structure and function

Green Mediterranean diet reshapes DNA methylation, boosts metabolism

Study shows how IgA acts as a "tuner" to keep the immune system in check

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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