Induced Pluripotent Stem Cells News and Research

RSS

Human cardiac organoids for modeling physiological conditions during a heart attack

In the U.S., someone has a heart attack every 40 seconds, and yet researchers have not had a model that fully mimics what occurs in the human heart after a heart attack.

12 Jun 2020

Engineered natural killer cells show promise for treating a form of leukemia

Using induced pluripotent stem cells (iPSCs) and deleting a key gene, researchers at University of California San Diego School of Medicine have created natural killer cells - a type of immune cell - with measurably stronger activity against a form of leukemia, both in vivo and in vitro.

12 Jun 2020

Study identifies potential biomarker for prescreening donor's stem cells

A new study released today in STEM CELLS addresses a significant problem that has been confronting human mesenchymal stem cells (hMSCs) therapy.

8 Jun 2020

Creating hair-bearing human skin becomes a reality

For more than 40 years, scientists and commercial companies have been recreating human skin in laboratories around the world. Yet all of these products lack important aspects of normal skin--hair, nerves, and fat.

5 Jun 2020

Study resolves contradictions surrounding p53 gene's role in pluripotent stem cell differentiation

The gene p53 is extremely important in cell biology and, hence, the world of cell replacement therapy. Its role is to regulate the cell cycle and halt the formation of tumors, leading to its nickname the "tumor suppressor gene."

1 Jun 2020

Stem cell model sheds new light on the devastating process of neurodegeneration

A new study published today in Neuron led by The New York Stem Cell Foundation Research Institute's Valentina Fossati, Ph.D., creates astrocytes - an integral support cell in the brain - from stem cells and shows that in disease-like environments, these normally helpful cells can turn into neuron-killers.

1 Jun 2020

Study provides groundwork for restoring nerve-muscle connection in ALS

Patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, lose muscle control as nerve cells or neurons in the brain and spinal cord degenerate and can no longer send signals to muscles.

28 May 2020

Researchers grow lung organoids from stem cells for Sars-Cov-2 research

A Bochum-based team intends to use organoids from stem cells to study the progression of Sars-CoV-2 infection and to identify antiviral substances.

28 May 2020

Updates on stem cell therapeutics and regenerative medicine

Stem cell and regenerative medicine research is an important area of clinical research which promises to change the face of medicine as it will be practiced in the years to come.

27 May 2020

Biophysicists determine the optimal age of reprogrammed stem cells

Biophysicists from the Moscow Institute of Physics and Technology and Vladimirsky Moscow Regional Clinical Research Institute have determined the optimal age of reprogrammed stem cells suitable for restoring heart tissue.

26 May 2020

Scientists use new model to develop cancer stem cells

Liver cancer is one of the deadliest cancers. It is insidious and does not present symptoms until it has progressed considerably, at which point, treatment options are limited and chances of survival are low. The most common type of liver cancer is hepatocellular carcinoma (HCC).

21 May 2020

Researchers identify a group of dysregulated genes in autism

Autism has long been associated only with behavioral and environmental factors, but the role of genetics in its development is now increasingly evident. Some 100 genes have been found to play a role in autism spectrum disorder, and another thousand are being studied to the same end.

14 May 2020

The Role of Microphysiological Systems for Oncology and Stem Cell Research

In this interview, Dr. Nancy Allbritton from The Allbritton Lab talks to News-Medical and Life Sciences about the revolutionary technology and techniques for the application of new technologies for oncology and stem cell research.

From Pittcon 6 May 2020

Study marks a major step towards beta cell replacement therapy

The loss of insulin-secreting beta cells by autoimmune destruction leads to type 1 diabetes. Clinical islet cell transplantation has the potential to cure diabetes, but donor pancreases are rare.

28 Apr 2020

New brain cell models created to evaluate therapies for Sanfilippo C syndrome

The Sanfilippo syndrome type C is a severe neurodegenerative disease which appearws during the first years of life and for which there is no treatment yet.

24 Apr 2020

Study: Patients’ genetically edited stem cells successfully reversed diabetes in mice

Using induced pluripotent stem cells produced from the skin of a patient with a rare, genetic form of insulin-dependent diabetes called Wolfram syndrome, researchers transformed the human stem cells into insulin-producing cells and used the gene-editing tool CRISPR-Cas9 to correct a genetic defect that had caused the syndrome.

22 Apr 2020

Study creates a new platform to study single-cell genomics of many diseases

Although advances in genetics and genomics reveal numerous disease-associated gene mutations, physicians and researchers still wrestle with the tricky challenge of linking those mutations to actual disease-causing processes.

22 Apr 2020

Accelerating Antibody Discovery with Next-Generation Single-Cell Analysis

Accelerating antibody discovery using picodroplet technology for single cell analysis to condense discovery times down to 1-2 days.

From Fluidic Sciences and Sphere Bio 22 Apr 2020

Exercise enhances muscle-repair capabilities in old mice, Stanford study shows

A nightly jaunt on the exercise wheel enhances muscle-repair capabilities in old mice, according to a new study by researchers at Stanford School of Medicine.

13 Apr 2020

New technology enables on-demand production of nutrients during space missions

On March 9, 2020, a Dragon cargo spacecraft arrived at the International Space Station carrying dozens of scientific experiments as a part of SpaceX's 20th cargo resupply mission. Now, Dragon heads home. On April 7, it is scheduled to undock from station, bringing samples, hardware and data from completed investigations back to Earth on its return trip.

8 Apr 2020