Omicron News and Research

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Research finds SARS-CoV-2 Omicron variant to be more fatal than seasonal influenza

Adults hospitalized with the SARS-CoV-2 Omicron variant have a higher death rate than those hospitalized with seasonal influenza, even though Omicron is considered less virulent with lower case fatality rates than the delta and alpha strains, new research being presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark (15-18 April) suggests.

7 Apr 2023

Nasal SARS-CoV-2 vaccine outperforms existing vaccines in preclinical trial

Researchers assess the role of the live-attenuated vaccine sCPD9 in inducing systemic and mucosal immunity against SARS-CoV-2 variants.

6 Apr 2023

mAb therapy reduces risk of hospitalization and death against Alpha, Delta, and Omicron variants

Researchers assess the efficacy of monoclonal antibodies in treating COVID-19 caused by different viral variants.

6 Apr 2023

Long COVID's significant impact on health calls for greater consideration in pandemic policy planning

Researchers estimated long coronavirus disease (COVID)-associated morbidity in the Australian population.

6 Apr 2023

Study explores the species-specific use of ACE2 receptors by human and animal coronaviruses

Researchers assessed the ability of spike proteins from 24 animal or human coronaviruses to utilize angiotensin-converting enzyme 2.

5 Apr 2023

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

Researchers assessed the extent of SARS-CoV-2 Omicron VOC BA.5 sub-VOC infection-associated brain infection and death.

5 Apr 2023

The association between neutralizing antibody response breadth and long COVID symptoms

Researchers assessed neutralizing antibody responses before and after severe acute respiratory syndrome coronavirus 2 Omicron.

5 Apr 2023

Long-term protection and high efficacy of bivalent BA.1 booster confirmed in older adults

Researchers estimated the duration of protection with monovalent vaccination and the efficacy of bivalent vaccine boosters.

5 Apr 2023

Study indicates an increased likelihood of COVID-19-associated hospitalization among children living in rural areas

Researchers investigated characteristics of SARS-CoV-2 infections related to pediatric hospitalizations.

4 Apr 2023

Pre-existing immunity shapes mucosal SARS-CoV-2-specific antibody responses

In a recent study, researchers assessed serological and mucosal immunity among three differing cohorts.

4 Apr 2023

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Researchers discover a small molecule drug candidate that could provide immediate protection against infection with SARS-CoV-2.

4 Apr 2023

Pediatric SARS-CoV-2 seroprevalence higher than official case reports

Researchers conduct a cross-sectional survey to estimate SARS-CoV-2 antibodies in children.

3 Apr 2023

Updated booster shots vital for keeping COVID-19 in check

Between natural infection and a global vaccination campaign, most people now have some immunity against the virus that causes COVID-19.

3 Apr 2023

Study identifies ultra-broad SARS-CoV-2 neutralizing antibodies that target various spike epitopes

Researchers screened the circulating B lymphocyte repertoires of coronavirus disease 2019 convalescents and vaccines using multiplexed antigen panels.

3 Apr 2023

Tighter core of SARS-CoV-2 spike protein in new variants may have increased the virus's fitness

Just as a tight core is a component of good physical fitness for humans, helping to stabilize our bodies, mutations that tightened the core of the SARS-CoV-2 spike protein in new variants may have increased the virus's fitness.

31 Mar 2023

Do two or more mRNA vaccine doses provide additional protection in patients with prior COVID-19 infection?

Researchers conducted a retrospective cohort study among vaccinated and unvaccinated COVID-19 patients between December 16, 2020, and March 15, 2022, in the USA.

30 Mar 2023

Study finds that current antiviral drugs retain efficacy against newly emerged Omicron subvariants

Researchers assessed the efficacy of antiviral medications against novel Omicron subvariants.

30 Mar 2023

Study finds minimal impact of SARS-CoV-2 genome variability on current diagnostic molecular systems

The authors of a new study under review at the journal Scientific Reports and currently posted to the Research Square preprint* server proposed a novel analysis pipeline to help identify mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcription-polymerase chain reaction (RT-PCR) primer regions.

29 Mar 2023

Newly designed molecule disrupts the infection mechanism of SARS-CoV-2

A team of scientists led by the Department of Energy's Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.

28 Mar 2023

New nanomaterials-based sensor detects flu and COVID-19 in just 10 seconds

Have a cough, sore throat and congestion? Any number of respiratory viruses could be responsible. Conventional tests can identify certain likely culprits by relying on chemical reactions, but some researchers want to swap chemistry for electrical changes sensed by nanomaterials.

28 Mar 2023

Omicron News and Research

Research finds SARS-CoV-2 Omicron variant to be more fatal than seasonal influenza

Nasal SARS-CoV-2 vaccine outperforms existing vaccines in preclinical trial

mAb therapy reduces risk of hospitalization and death against Alpha, Delta, and Omicron variants

Long COVID's significant impact on health calls for greater consideration in pandemic policy planning

Study explores the species-specific use of ACE2 receptors by human and animal coronaviruses

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

The association between neutralizing antibody response breadth and long COVID symptoms

Long-term protection and high efficacy of bivalent BA.1 booster confirmed in older adults

Study indicates an increased likelihood of COVID-19-associated hospitalization among children living in rural areas

Pre-existing immunity shapes mucosal SARS-CoV-2-specific antibody responses

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Pediatric SARS-CoV-2 seroprevalence higher than official case reports

Updated booster shots vital for keeping COVID-19 in check

Study identifies ultra-broad SARS-CoV-2 neutralizing antibodies that target various spike epitopes

Tighter core of SARS-CoV-2 spike protein in new variants may have increased the virus's fitness

Do two or more mRNA vaccine doses provide additional protection in patients with prior COVID-19 infection?

Study finds that current antiviral drugs retain efficacy against newly emerged Omicron subvariants

Study finds minimal impact of SARS-CoV-2 genome variability on current diagnostic molecular systems

Newly designed molecule disrupts the infection mechanism of SARS-CoV-2

New nanomaterials-based sensor detects flu and COVID-19 in just 10 seconds

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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